Silicosis Diagnosed Using Transbronchial Lung Biopsy: The Pivotal Role of Occupational History. [PDF]
Clin Case RepABSTRACT Pulmonary silicosis, a preventable occupational lung disease caused by chronic inhalation of crystalline silica dust in industries like construction, mining, and stone masonry, remains underdiagnosed in TB‐endemic regions due to overlapping clinical and radiological features.
Ng BH +6 more
europepmc +2 more sources
Dihydroquercetin Attenuates Silica-Induced Pulmonary Fibrosis by Modulating the Gut Microbiota and the Serum Metabolites in Mice. [PDF]
Food Sci Nutr(1) DHQ can attenuate silica‐induced inflammation and pulmonary fibrosis in the C57BL/6 mice. (2) The beneficial effects of DHQ were primarily attributed to the alteration of gut microbiota (particularly Muribaculaceae and Lactobacillus) mediated by serum metabolites.
Ke Z +5 more
europepmc +2 more sources
Environmental Impact of Silicic Magmatism in Large Igneous Province Events
Geophysical Monograph Series, Page 133-151., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Scott E. Bryan
wiley +2 more sources
Caplan Syndrome: A Case Report. [PDF]
Clin Case RepSwelling of metacarpophalangeal joints, proximal interphalangeal joints with spindle‐shaped aspects at proximal interphalangeal joints. ABSTRACT Caplan syndrome, known as rheumatoid pneumoconiosis, is a combination of silicosis and rheumatoid arthritis.
Laouali AMM +12 more
europepmc +2 more sources
BMC Pulmonary Medicine, 2021 Background Silicosis is a progressive pneumoconiosis characterized by interstitial fibrosis following exposure to silica dust. The role of metabolic dysregulation in the pathogenesis of silicosis has not been investigated in detail.
Changjiang Xue +4 more
doaj +1 more source
Frontiers in Immunology, 2022 ObjectiveTo evaluate the association between single-nucleotide polymorphisms (SNPs) in RNA-seq identified mRNAs and silicosis susceptibility.MethodsA comprehensive RNA-seq was performed to screen for differently expressed mRNAs in the peripheral blood ...
Yan Zhou +12 more
doaj +1 more source
Journal of Family Medicine and Primary Care, 2021 Context: Silicosis is a progressive, irreversible and incurable respiratory morbidity and often becomes a cause for pre-mature mortality among occupationally silica dust-exposed workers in India and similar countries.
Subroto S Nandi +2 more
doaj +1 more source
Targeting the Secretin Receptor in Macrophages Attenuates Silica-Induced Pulmonary Fibrosis. [PDF]
Cell ProlifTargeting macrophage SCTR mitigates integrated profibrotic, inflammatory, ER stress, and senescent pathways, preserving lung function and revealing a novel therapeutic strategy for silicosis.
Li Y +12 more
europepmc +2 more sources
Trends in silicosis prevalence and the healthy worker effect among gold miners in South Africa: a prevalence study with follow up of employment status. [PDF]
, 2015 BACKGROUND: Given the intimate association between silicosis and tuberculosis, understanding the epidemiology of the South African gold mining industry silicosis epidemic is essential to current initiatives to control both silicosis and tuberculosis in ...
Churchyard, Gavin +5 more
core +3 more sources
Review on role of NLRP3 inflammasome in pathogenesis of silicosis
环境与职业医学, 2022 Silicosis is one of the most common forms of pneumoconiosis globally. Workers who engage in mining, construction, ceramics, and many other industries have a high risk of developing silicosis. Chronic and repeated inhalation of free silica (SiO2) dust (
Zhenzhen FAN +6 more
doaj +1 more source