Results 31 to 40 of about 41,841 (256)

Global and national burden and trends of mortality and disability-adjusted life years for silicosis, from 1990 to 2019: results from the Global Burden of Disease study 2019

BMC Pulmonary Medicine, 2022
Background Silicosis, as an important type of pneumoconiosis, leads to progressive and irreversible conditions from the beginning of inflammation and fibrosis. However, the data on the global burden of silicosis and long-term trends were limited. Methods
Shimin Chen, Miao Liu, F. Xie
semanticscholar   +1 more source

Distinct metabolic features in the plasma of patients with silicosis and dust-exposed workers in China: a case–control study

BMC Pulmonary Medicine, 2021
Background Silicosis is a progressive pneumoconiosis characterized by interstitial fibrosis following exposure to silica dust. The role of metabolic dysregulation in the pathogenesis of silicosis has not been investigated in detail.
Changjiang Xue, Na Wu, Yali Fan, Jing Ma, Qiao Ye   +4 more
doaj   +1 more source

Integrating RNA-Seq With GWAS Reveals a Novel SNP in Immune-Related HLA-DQB1 Gene Associated With Occupational Pulmonary Fibrosis Risk: A Multi-Stage Study

Frontiers in Immunology, 2022
ObjectiveTo evaluate the association between single-nucleotide polymorphisms (SNPs) in RNA-seq identified mRNAs and silicosis susceptibility.MethodsA comprehensive RNA-seq was performed to screen for differently expressed mRNAs in the peripheral blood ...
Yan Zhou, Yingyi Zhang, Rui Zhao, Zhounan Cheng, Minzhu Tang, Anni Qiu, Yang Dong, Yihua Lu, Yulong Lian, Xun Zhuang, Tian Tian, Wei Wang, Minjie Chu   +12 more
doaj   +1 more source

The association between silica exposure, silicosis and tuberculosis: a systematic review and meta-analysis

BMC Public Health, 2021
Background While the association between occupational inhalation of silica dust and pulmonary tuberculosis has been known for over a century, there has never been a published systematic review, particularly of experience in the current era of less severe
R. Ehrlich, Paula Akugizibwe, N. Siegfried, D. Rees   +3 more
semanticscholar   +1 more source

Demographic, exposure and clinical characteristics in a multinational registry of engineered stone workers with silicosis

Occupational and Environmental Medicine, 2022
Objectives To investigate differences in workplace exposure, demographic and clinical findings in engineered stone (ES) workers from a multinational consortium using the Engineered Stone Silicosis Investigators (ESSI) Global Silicosis Registry.
J. Hua, L. Zell-Baran, L. Go, M. Kramer, Johanna B Van Bree, D. Chambers, D. Deller, K. Newbigin, M. Matula, E. Fireman, M. Dahbash, C. Martínez-González, A. León-Jiménez, C. Sack, J. Ferrer, A. Villar, K. Almberg, R. Cohen, C. Rose   +18 more
semanticscholar   +1 more source

Review on role of NLRP3 inflammasome in pathogenesis of silicosis

环境与职业医学, 2022
Silicosis is one of the most common forms of pneumoconiosis globally. Workers who engage in mining, construction, ceramics, and many other industries have a high risk of developing silicosis. Chronic and repeated inhalation of free silica (SiO2) dust (
Zhenzhen FAN, Yehong ZHAO, Bing LI, Yang LIU, Junyu JIANG, Min MU, Xinrong TAO   +6 more
doaj   +1 more source

The Triple Burden of Tuberculosis, Human Immunodeficiency Virus and Silicosis among Artisanal and Small-Scale Miners in Zimbabwe

International Journal of Environmental Research and Public Health, 2022
Artisanal and small-scale mining is characterized by an excessive exposure to silica-containing dust, overcrowding, poor living conditions and limited access to primary health services. This poses a risk to tuberculosis, HIV infection and silicosis.
D. Moyo, R. Ncube, Fungai Kavenga, L. Chikwava, Tawanda Mapuranga, Nathan Chiboyiwa, Chipo Chimunhu, Frank Mudzingwa, O. Muzvidziwa, Petronella Ncube, Tariro Christwish Mando, F. Moyo, B. Chigaraza, Hellen Masvingo, C. Timire   +14 more
semanticscholar   +1 more source

Inflammatory indices obtained from routine blood tests show an inflammatory state associated with disease progression in engineered stone silicosis patients

Scientific Reports, 2022
Patients with silicosis caused by occupational exposure to engineered stone (ES) present a rapid progression from simple silicosis (SS) to progressive massive fibrosis (PMF).
Alejandro García-Núñez, G. Jiménez-Gómez, Antonio Hidalgo-Molina, J. Córdoba-Doña, A. León-Jiménez, A. Campos‐Caro   +5 more
semanticscholar   +1 more source

Social determinants of an occupational lung disease: Workers’ narratives on silicosis

SSM: Qualitative Research in Health, 2023
Silicosis is a preventable occupational lung disease caused by inhaled silica dust. Solutions to prevent silicosis ranging from engineering controls to respirator use have been validated for nearly a century, but many workers are still at-risk of this ...
Yanni Liang, Katherine E. McCoy, Carrie D. Tomasallo, Jonathan G. Meiman   +3 more
doaj   +1 more source

Development of nintedanib nanosuspension for inhaled treatment of experimental silicosis

Bioengineering & Translational Medicine, 2022
Silicosis is an irreversible and progressive fibrotic lung disease caused by massive inhalation of crystalline silica dust at workplaces, affecting millions of industrial workers worldwide.
L. H. Andrade da Silva, J. B. Vieira, M. R. Cabral, M. Antunes, Daiheon Lee, F. Cruz, J. Hanes, P. Rocco, M. Morales, J. S. Suk   +9 more
semanticscholar   +1 more source