Results 11 to 20 of about 14,228 (122)

Decoding HIV-1 Next Move Through Matrix Protein p17 Quasi-Species. [PDF]

Microbiologyopen
HIV‐1 mutants expressing clonogenic HIV‐1 matrix protein p17 variants (vp17s) are spreading, increasing their prevalence worldwide. In RNA viruses, quasi‐species are transmitted among hosts, leading to the generation of new master sequences. We developed a next‐generation sequence approach to evaluate the frequency of vp17 quasi‐species in people ...
Messali S, Bertelli A, Giovanetti M, Sclavi L, Ciccozzi M, Slevin M, Caruso A, Caccuri F.   +7 more
europepmc   +2 more sources

Natural host genetic resistance to lentiviral CNS disease: a neuroprotective MHC class I allele in SIV-infected macaques. [PDF]

PLoS ONE, 2008
Human immunodeficiency virus (HIV) infection frequently causes neurologic disease even with anti-retroviral treatment. Although associations between MHC class I alleles and acquired immunodeficiency syndrome (AIDS) have been reported, the role MHC class ...
Joseph L Mankowski, Suzanne E Queen, Caroline S Fernandez, Patrick M Tarwater, Jami M Karper, Robert J Adams, Stephen J Kent   +6 more
doaj   +1 more source

Evolution of drug resistance drives destabilization of flap region dynamics in HIV-1 protease

Biophysical Reports, 2023
The HIV-1 protease is one of several common key targets of combination drug therapies for human immunodeficiency virus infection and acquired immunodeficiency syndrome.
Madhusudan Rajendran, Maureen C. Ferran, Leora Mouli, Gregory A. Babbitt, Miranda L. Lynch   +4 more
doaj   +1 more source

Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys. [PDF]

PLoS ONE, 2016
Aberrant turnover of memory CD4+ T-cells is central to Acquired Immunodeficiency Syndrome (AIDS) progression. Understanding the relationship between the turnover of CD4+ subsets and immunological homeostasis during simian immunodeficiency virus (SIV ...
Alexandra M Ortiz, Diane G Carnathan, Joana Yu, Katherine M Sheehan, Peter Kim, Arnold Reynaldi, Thomas H Vanderford, Nichole R Klatt, Jason M Brenchley, Miles P Davenport, Guido Silvestri   +10 more
doaj   +1 more source

Repressive effect of primary virus replication on superinfection correlated with gut-derived central memory CD4(+) T cells in SHIV-infected Chinese rhesus macaques. [PDF]

PLoS ONE, 2013
A possible mechanism of susceptibility to superinfection with simian-human immunodeficiency virus (SHIV)-1157ipd3N4 was explored in twelve SHIVSF162P3-infected Chinese rhesus macaques.
Jing Xue, Zhe Cong, Jing Xiong, Wei Wang, Hong Jiang, Ting Chen, Fangxin Wu, Kejian Liu, Aihua Su, Bin Ju, Zhiwei Chen, Marcelo A Couto, Qiang Wei, Chuan Qin   +13 more
doaj   +1 more source

Identification and Verification of Immune Metabolism-Related Biomarkers and Immune Infiltration Landscape for Pediatric Opsoclonus Myoclonus Ataxia Syndrome in Neuroblastoma. [PDF]

CNS Neurosci Ther
Based on the GEO database and GeneCards database, 1785 immune metabolism genes, 1879 DEGs, and 1560 module genes were screened out. After taking the intersection, 162 differential immune metabolic–related genes were obtained. Four diagnostic biomarker genes, TRAF3IP2, RIPK1, KEAP1, and DPP4, were screened out through three machine learning algorithms ...
Li M, Li J.
europepmc   +2 more sources

Simian Models of Acquired Immunodeficiency Syndrome (AIDS): A Review [PDF]

Veterinary Pathology, 1986
Reports of the unprecedented occurrence of Kaposi’s sarcoma and fatal Pneumocystis carinii pneumonia in previously healthy homosexual men in New York and California in 198 1 heralded the onset of the current human epidemic known as the acquired immunodeficiency syndrome Since those initial reports, the incidence and spread of this disease have ...
openaire   +2 more sources

Isolation and Characterization of Simian Retrovirus Type D from Macaca fascicularis and M. nemestrina in Indonesia

Microbiology Indonesia, 2010
Simian type D retroviruses (SRVs) are one of the causative agents of simian acquired immunodeficiency syndrome (AIDS) in Asian macaques. In the past, SRV isolates from macaques had only been identified at the US primate centers, outside the country of ...
DIAH ISKANDRIATI, UUS SAEPULOH, SILMI MARIYA, RICHARD F GRANT, DEDY DURYADI SOLIHIN, DONDIN SAJUTHI, JOKO PAMUNGKAS   +6 more
doaj   +1 more source

Expression of Simian Retrovirus Type D Serotype 2 Envelope in Insect Cell Using Baculovirus Expression Vector System

Microbiology Indonesia, 2010
Simian retrovirus type-D (SRV) is a causative agent of simian acquired immunodeficiency syndrome in Asian macaques, and can serve as a viral model in understanding of retrovirus infection because of some similarities to human AIDS pathogenesis.
DIAH ISKANDRIATI, MOHAMAD SADIKIN, JOKO PAMUNGKAS   +2 more
doaj   +1 more source

Immunologic Alterations in Monkeys with Simian Acquired Immunodeficiency Syndrome (SAIDS)

Experimental Biology and Medicine, 1985
Levels of lymphocyte responsiveness to T- and B-cell-specific mitogens and expressions of Ia, T4, T8, and T11 surface markers were monitored during the course of Simian acquired immunodeficiency syndrome (SAIDS) in four Rhesus macaques that either died or became ill and survived.
D B, Budzko, D L, Madden, W T, London, J L, Sever   +3 more
openaire   +2 more sources