Results 271 to 280 of about 93,598 (304)
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Conservation of a dinucleotide simple sequence repeat locus in sharks
Molecular Phylogenetics and Evolution, 2002Recent studies indicate that the flanking region and repeat motif structure of conserved microsatellite loci are useful for phylogenetic inference. Most comparative studies of microsatellite loci involve relatively closely related species, however, primarily because primers developed for one species often amplify only related species.
Andrew P, Martin +3 more
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Simple sequence repeats for germplasm analysis and mapping in maize
Genome, 1996Simple sequence repeats (SSRs) are a relatively new class of DNA markers consisting of short runs of tandemly repeated sequence motifs evenly distributed throughout eukaryotic genomes. Owing to the high rate of variation in the number of repeat units, the polymorphism level shown by SSRs is high.
G, Taramino, S, Tingey
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Evolution of Simple Sequence Repeats as Mutable Sites
2012Because natural selection is commonly presumed to minimize mutation rates, the discovery of mutationally unstable simple sequence repeats (SSRs) in many functional genomic locations came as a surprise to many biologists. Whether such SSRs persist in spite of or because of their intrinsic mutability-whether they constitute a genetic burden or an ...
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Rapid Evolution of Simple Sequence Repeat Induced by Allopolyploidization
Journal of Molecular Evolution, 2009Microsatellite evolution normally occurs in diploids. Until now, there has been a lack of direct experimental evidence for microsatellite evolution following allopolyploidization. In the present study, F(1) hybrids and newly synthesized allopolyploids were derived from Triticum aestivum Chinese Spring x Secale cereale Jinzhou-heimai.
Zongxiang, Tang +3 more
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Simple sequence repeats in proteins and their significance for network evolution
Gene, 2005Only 5-6% of mammalian genomes are genes; the remainders are made up primarily of transposable elements and different types of simple sequence repeat (SSRs) (micro- and minisatellites and cryptic repeats), which tend to accumulate in organisms with larger genomes.
John M, Hancock, Michelle, Simon
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Simple sequence repeats as a source of quantitative genetic variation
Trends in Genetics, 1997Most traits in biological populations appear to be under stabilizing selection, which acts to eliminate quantitative genetic variation. Yet, virtually all measured traits in biological populations continue to show significant quantitative genetic variation.
Y, Kashi, D, King, M, Soller
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Instability of simple sequence repeats in a mammalian cell line
Human Molecular Genetics, 1994Short tandem repeat sequences in the mammalian genome are considered to be unstable, since many of them are polymorphic in length; however, the extent of this instability has been difficult to quantitate. We have directly determined the rate of mutation of a simple sequence repeat in a mammalian cell line.
R A, Farber +4 more
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Identification of a protein encoded by a mouse simple repeated sequence.
Journal of submicroscopic cytology and pathology, 1994In order to study the possibility that a mouse repeated 'simple sequence', containing an ORF, could encode a protein, we inserted a fragment of a cDNA clone into the expression vector pEX31C. The fragment containing the short sequence 'CAGAGAGG' was expressed as MS2 polymerase fusion protein in Escherichia coli.
Di Carlo M +4 more
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Simple DNA Sequence (Simple Repeat, Simple Sequence Repeat)
2004John M. Hancock, Katheleen Gardiner
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