Results 271 to 280 of about 5,215,765 (304)
Some of the next articles are maybe not open access.
Rapid Evolution of Simple Sequence Repeat Induced by Allopolyploidization
Journal of Molecular Evolution, 2009Microsatellite evolution normally occurs in diploids. Until now, there has been a lack of direct experimental evidence for microsatellite evolution following allopolyploidization. In the present study, F(1) hybrids and newly synthesized allopolyploids were derived from Triticum aestivum Chinese Spring x Secale cereale Jinzhou-heimai.
Zongxiang, Tang +3 more
openaire +2 more sources
Evolution of Simple Sequence Repeats as Mutable Sites
2012Because natural selection is commonly presumed to minimize mutation rates, the discovery of mutationally unstable simple sequence repeats (SSRs) in many functional genomic locations came as a surprise to many biologists. Whether such SSRs persist in spite of or because of their intrinsic mutability-whether they constitute a genetic burden or an ...
openaire +2 more sources
Simple sequence repeats in proteins and their significance for network evolution
Gene, 2005Only 5-6% of mammalian genomes are genes; the remainders are made up primarily of transposable elements and different types of simple sequence repeat (SSRs) (micro- and minisatellites and cryptic repeats), which tend to accumulate in organisms with larger genomes.
John M, Hancock, Michelle, Simon
openaire +2 more sources
Simple sequence repeats as a source of quantitative genetic variation
Trends in Genetics, 1997Most traits in biological populations appear to be under stabilizing selection, which acts to eliminate quantitative genetic variation. Yet, virtually all measured traits in biological populations continue to show significant quantitative genetic variation.
Y, Kashi, D, King, M, Soller
openaire +2 more sources
Instability of simple sequence repeats in a mammalian cell line
Human Molecular Genetics, 1994Short tandem repeat sequences in the mammalian genome are considered to be unstable, since many of them are polymorphic in length; however, the extent of this instability has been difficult to quantitate. We have directly determined the rate of mutation of a simple sequence repeat in a mammalian cell line.
R A, Farber +4 more
openaire +2 more sources
Simple DNA Sequence (Simple Repeat, Simple Sequence Repeat)
2004John M. Hancock, Katheleen Gardiner
openaire +1 more source
Identification of a protein encoded by a mouse simple repeated sequence.
Journal of submicroscopic cytology and pathology, 1994In order to study the possibility that a mouse repeated 'simple sequence', containing an ORF, could encode a protein, we inserted a fragment of a cDNA clone into the expression vector pEX31C. The fragment containing the short sequence 'CAGAGAGG' was expressed as MS2 polymerase fusion protein in Escherichia coli.
Di Carlo M +4 more
openaire +2 more sources
Repeat offenders: Simple repeat sequences and complex genetic problems
Human Mutation, 1996Richards, R., Sutherland, G.
openaire +2 more sources