Novel Alpha‐, Beta‐, and Gammaherpesviruses in Neotropical Carnivores of Brazil
The knowledge regarding infectious agents affecting wildlife is crucial for species’ conservation. We hypothesized that herpesviruses are present in wild Neotropical carnivores. Herein, we used DNA polymerase and glycoprotein B broad‐spectrum PCRs to molecularly survey the presence of herpesviruses in spleen and/or lung samples of 53 wild Neotropical ...
Ana Carolina Ewbank +10 more
wiley +1 more source
El Herpes simple genital, el Condiloma acuminado y el Síndrome de inmunodeficiencia adquirida son infecciones de transmisión sexual viral no curable, con aumento de su incidencia en el área de salud del policlínico “Dr.
Eldir Diéguez Velázquez +3 more
doaj
Control of HSV-1 latency in human trigeminal ganglia—current overview [PDF]
Although recurrent Herpes simplex virus type 1 (HSV-1) infections are quite common in humans, little is known about the exact molecular mechanisms involved in latency and reactivation of the virus from its stronghold, the trigeminal ganglion.
Derfuss, Tobias, Held, Kathrin
core
Tegument Assembly and Secondary Envelopment of Alphaherpesviruses. [PDF]
Alphaherpesviruses like herpes simplex virus are large DNA viruses characterized by their ability to establish lifelong latent infection in neurons. As for all herpesviruses, alphaherpesvirus virions contain a protein-rich layer called "tegument" that ...
Crump, Colin M +2 more
core +3 more sources
A Herpes Simplex Virus 2 (HSV-2) Glycoprotein D-expressing Nonreplicating Dominant-Negative HSV-2 Virus Vaccine Is Superior to a gD2 Subunit Vaccine against HSV-2 Genital Infection in Guinea Pigs [PDF]
We recently constructed a novel non-replicating dominant-negative HSV-2 recombinant viral vaccine (CJ2-gD2) capable of expressing various HSV-2 antigens that are dominant targets of HSV-2-specific CD8 T-cell response.
Balliet, John W. +4 more
core +2 more sources
Alphaherpesviruses are ubiquitous DNA viruses and include the human pathogens herpes simplex virus 1 (HSV-1) and HSV-2 and are significant causes of ulcerative mucosal sores, infectious blindness, encephalitis, and devastating neonatal disease ...
A. Charron +4 more
semanticscholar +1 more source
A red/far-red light-responsive bi-stable toggle switch to control gene expression in mammalian cells [PDF]
Growth and differentiation of multicellular systems is orchestrated by spatially restricted gene expression programs in specialized subpopulations. The targeted manipulation of such processes by synthetic tools with high-spatiotemporal resolution could ...
Busacker, Moritz +5 more
core +1 more source
Herpes simplex virus hepatitis 4 years after liver transplantation [PDF]
If not promptly recognized and treated, herpes simplex virus (HSV) hepatitis is associated with a high mortality. A patient transplanted for primary sclerosing cholangitis required, 4 years later, a colectomy for a steroid-resistant flare of ulcerative ...
Bernasch, Dirke +4 more
core
Rapid Evolution of BRCA1 and BRCA2 in Humans and Other Primates [PDF]
The maintenance of chromosomal integrity is an essential task of every living organism and cellular repair mechanisms exist to guard against insults to DNA.
Demogines, Ann M. +6 more
core +3 more sources
Recurring eczema herpeticum complicated by herpetic meningitis and staphylococcal bacteremia
Background: Eczema Herpeticum (EH) is a dermatological emergency that may progress to viral meningitis in patients not treated urgently. We present a case of recurrent EH in a young, immunocompetent patient complicated by progressing herpetic meningitis ...
Morgan C. Lain +8 more
doaj +1 more source

