Results 211 to 220 of about 1,429,075 (291)

Optimizing the zymogram of exogenous proteases in broiler diets by in vitro simulated gastrointestinal digestion and response surface methodology. [PDF]

Sci Rep
Liu Y, Liu S, Chen F, Liu S, Lin Q, Dai Q.   +5 more
europepmc   +1 more source

A Versatile Microfluidic Manufacturing Platform for Macroscale Multicore Hydrogel Capsules Toward Programmable Oral Delivery of Therapeutics

Small, EarlyView.
This study presents a microfluidic fabrication method for millimeter‐scale multicore hydrogel capsules containing multiple aqueous cores physically isolated by oil layers. These macrocapsules exhibit mechanical and chemical robustness effectively protecting cargos under simulated gastric conditions.
Hye‐Seon Jeong, Chae‐Hee Park, Yoon Choi, Hyunmin Yi, Chang‐Hyung Choi   +4 more
wiley   +1 more source

Engineering metal‐organic framework‐based smart porous nanoplatforms for targeted therapy and theranostic applications

Smart Molecules, EarlyView.
MOFs offer high porosity and tunability for biomedical applications, especially in cancer therapy via ROS generation and targeted delivery. Though toxicity, stability, and scalability remain key clinical challenges. Drug loading in MOFs exceeds 60%–70% with controlled release behavior.
Jagabandhu Bag, Subhasis Banerjee, Sabyasachi Banerjee, Sourav De, S. K. Ashok Kumar, Yan‐Jye Shyong, Subhankar Mukhopadhyay   +6 more
wiley   +1 more source

Casein Glycomacropeptide Regulates Gene Expression in Intestinal Epithelial Cells: Effect of Simulated Gastrointestinal Digestion and Peptide Microencapsulation. [PDF]

J Agric Food Chem
Cian RE, Tena-Garitaonaindia M, Sánchez de Medina F, Martínez-Augustin O.   +3 more
europepmc   +1 more source

From Consumer Plastics to Aquatic Toxicants: Oxidative and Endocrine Effects of Microplastics on Fathead Minnow (Pimephales promelas) Larvae

Environmental Toxicology, EarlyView.
ABSTRACT Secondary microplastics (MPs) from single‐use consumer products are rapidly becoming one of the most persistent and widespread pollutants of our time. Freshwater systems act as early sinks for MPs where fragmentation and additive leaching expose aquatic life to a broad spectrum of toxic compounds.
Alisha M. Janiga‐MacNelly, Andrew Barrick, Tham C. Hoang, Ramon Lavado   +3 more
wiley   +1 more source

Biopolymer-Based Microencapsulation of Procyanidins from Litchi Peel and Coffee Pulp: Characterization, Bioactivity Preservation, and Stability During Simulated Gastrointestinal Digestion. [PDF]

Polymers (Basel)
Vázquez-Nuñez MLÁ, Rocha-Guzmán NE, Aguilar-Zárate P, Rojas R, Martínez-Ávila GCG, Reyes A, Michel MR.   +6 more
europepmc   +1 more source

Climate‐Modulated Particle Toxicity: Acute Exposure to an Environmentally Informed Microplastic Mixture Induces Sex‐Dependent Systemic Reorganization in Swiss Mice

Environmental Toxicology, EarlyView.
ABSTRACT Microplastic (MP) pollution is widely recognized as an emerging environmental threat. Yet, most studies still rely on controlled experimental conditions that poorly reflect environmental complexity, potentially underestimating risks under realistic scenarios, particularly during short‐term exposures. Here, we tested whether acute oral exposure
Guilherme Malafaia, Rafaela Ribeiro de Brito, Aline Sueli de Lima de Rodrigues, Omar Cruz Santiago, Andrés Hugo Arias, Thiarlen Marinho da Luz   +5 more
wiley   +1 more source

Impact of Alcalase Hydrolysis and Simulated Gastrointestinal Digestion on the Release of Bioactive Peptides from Erythrina edulis (Chachafruto) Proteins. [PDF]

Int J Mol Sci
Correa JL, Zapata JE, Hernández-Ledesma B.   +2 more
europepmc   +1 more source

Bioaccessibility of Metal(loid)s From Anthropogenic Contamination in Dry Riverbed Sediments in the Cartagena–La Unión Mining District (Murcia, SE Spain): Implications for Human Health Risk Assessment

Environmental Toxicology, EarlyView.
ABSTRACT This study assessed the contamination levels, bioaccessibility, and potential health risks of As, Cd, Cu, Pb, and Zn in sediments from three dry riverbeds (El Beal‐EB, Las Matildes‐LM, and Ponce‐PN) impacted by historical mining activities in the Cartagena‐La Unión Mining District.
José Gregorio Cuevas, Ángel Faz, Silvia Martínez‐Martínez, Juan Carlos Beltrá, Jacinto Martínez, José A. Acosta   +5 more
wiley   +1 more source

Novel Whey Fermented Beverage Enriched with a Mixture of Juice Concentrates: Evaluation of Antimicrobial, Antioxidant, and Angiotensin I Converting Enzyme Inhibitory (ACE) Activities Before and After Simulated Gastrointestinal Digestion. [PDF]

Microorganisms
Kotsaki P, Aspri M, Papademas P.
europepmc   +1 more source