Results 71 to 80 of about 1,429,075 (291)

Can Storage Stability and Simulated Gastrointestinal Behavior Change the Cytotoxic Effects of Concentrated Guava Leaves Extract against Human Lung Cancer Cells?

Membranes
The influence of storage stability and simulated gastrointestinal behavior of different extracts of guava leaves extracts (NC: not concentrated, and C10 and C20: concentrated by nanofiltration) was evaluated based on their total phenolic compound (TPC ...
Giordana Demaman Arend, Silvani Verruck, Naira Fernanda Zanchett Schneider, Cláudia Maria Oliveira Simões, Marcus Vinícius Tres, Elane Schwinden Prudêncio, José Carlos Cunha Petrus, Katia Rezzadori   +7 more
doaj   +1 more source

Maillard-Type Protein–Polysaccharide Conjugates and Electrostatic Protein–Polysaccharide Complexes as Delivery Vehicles for Food Bioactive Ingredients: Formation, Types, and Applications

Gels, 2022
Due to their combination of featured properties, protein and polysaccharide-based carriers show promising potential in food bioactive ingredient encapsulation, protection, and delivery.
Xiaohong Sun, Hao Wang, Shengnan Li, Chunli Song, Songyuan Zhang, Jian Ren, Chibuike C. Udenigwe   +6 more
doaj   +1 more source

Intestinal health benefits of bovine whey proteins after simulated gastrointestinal digestion

, 2018
Bovine whey proteins are widely incorporated in foods for their nutritional, health promoting and functional value. However, whey proteins are readily digested in the upper gut.
A. R. Corrochano, L. Giblin, De Noni, Ivano, Kelly, Phil M., A. Ferraretto, Corrochano, Alberto R., I. De Noni, Corrochano, Alberto R, Stuknytè, Milda, Ferraretto, Anita, V. Buckin, Arranz Gutiérrez, Elena María, E. Arranz, Giblin, Linda, M. Stuknytė, Kelly,Phil M, Buckin, Vitaly, P. M. Kelly, Arranz, Elena   +18 more
core   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

Advanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu, Wanying Xiang, Xinyue Wang, Yue Pan, Jing Gao, Jiezhen Yang, Yufei Wang, Zhipu Zhu, Man Tong, Lei Jin, Yan Ye   +10 more
wiley   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Bioaccessibility and combined effect in transepithelial transport mechanisms of different dried thinned peach polyphenols

Food Chemistry: X
The present study evaluated the bioaccessibility and metabolic transport of different dried thinned peach polyphenols by using in vitro simulated digestion and Caco-2 cells models. Compared to freeze drying (FD) and natural drying (ND), hot air drying at
Chongting Guo, Xuan Li, Jiaxing Hu, Qingting Yu, Alberto Valdés, Alejandro Cifuentes, Jinfeng Bi   +6 more
doaj   +1 more source

Co-digestion of the mechanically recovered organic fraction of municipal solid waste with slaughterhouse wastes

, 2012
The current work aimed to resolve some long-standing questions about the potential benefits and limitations of co-digestion of slaughterhouse wastes.
Banks, C.J., Zhang, Y.
core   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

Functional vegan soups as bioactive food matrices: Evolution of polyphenol content and anticholinesterase activity during simulated gastrointestinal digestion

Journal of Functional Foods
This study investigated digestion-driven changes in polyphenol content, Maillard reaction products, and cholinesterase inhibitory activity in mushroom-, asparagus-, leek-, and sea buckthorn-based vegan soups. These polyphenol-rich, plant-based soups were
Dorota Gajowniczek-Ałasa, Joanna Grzelczyk, Ewa Baranowska-Wójcik, Dominik Szwajgier   +3 more
doaj   +1 more source