Results 81 to 90 of about 1,429,075 (291)

Assessment of the bioaccessibility of phenolics from Australian grown lettuces by in vitro simulated gastrointestinal digestion and colonic fermentation

, 2023
Assessment of the bioaccessibility of phenolics from Australian grown lettuces by in vitro simulated gastrointestinal digestion and colonic ...
H Wu (7724324), M Li (3216264), Z Liu (6098168), F Dunshea (13293273), Hafiz Suleria (13096467), Colin Barrow (13063191), M Shi (12793552), X Duan (9884207)   +7 more
core  

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

Advanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun, Ruiqi Wu, Qingshuang Tang, Yunli Xu, Wanrui Shi, Mengxin Wang, Haonan Wang, Yan Luo, Cheng Ma, Xiaolong Liang   +9 more
wiley   +1 more source

Effect of Simulated Gastrointestinal Digestion on Phytochemicals from Citrus-Derived Waste [PDF]

Global Journal of Environmental Science & Sustainability
Citrus is one of the most consumed fruit crops in the world, its peels are often discarded, contributing to environmental pollution. This study aims at extracting the bioactive compounds in these wastes and showing the possible effect of digestion on the
Jalil Idi James, Ishaq Anda Saalim, Maryam Dauda Hussaini, Ayuba Maina, Fatima Muhammed Abubakar, Fatima Mohammed Dalil, Promise Vincent Adiel, Lazarus J. Goje   +7 more
doaj   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

Phenolic bioaccessibility, antioxidant, and antidiabetic effects of indigenous fermented coffee beans after simulated gastrointestinal digestion and colonic fermentation

, 2023
Phenolic bioaccessibility, antioxidant, and antidiabetic effects of indigenous fermented coffee beans after simulated gastrointestinal digestion and colonic ...
Hafiz Suleria (13096467), Colin Barrow (13063191), Hanjing Wu (11825226), Frank R Dunshea (13451070)   +3 more
core  

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

Advanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa   +7 more
wiley   +1 more source

Epigenetic Silencing of CYYR1 Promotes Lung Adenocarcinoma Progression Through TRIM21‐Dependent Regulation of HMMR Stability

Advanced Science, EarlyView.
CYYR1 as an epigenetically dysregulated tumor‐suppressive factor that influences oncoprotein stability through TRIM21‐dependent HMMR regulation and reveals a potential therapeutic vulnerability in CYYR1‐deficient LUAD. The graphical illustration was created using FigDraw (www.figdraw.com).
Fengsheng Dai, Jingyi Tang, Huan Rong, Yu Wang, Xiangyi Zhou, Can Xu, Jianhua Wang, Lili Li, Yue Wu, Fei Deng, Dan Yang, Xiao Yang, Renyan Li, Yongzhong Wu, Dongxi Xiang, Tingxiu Xiang   +15 more
wiley   +1 more source

SIMGI: Dynamic Gastrointestinal Simulator of digestion and fermentation processes

, 2013
This work has been funded by the Spanish Ministry for Science and Innovation (AGL2009-13361-C02-00 and CSD2007-00063 Consolider Ingenio 2010 FUN-C-FOOD Projects) and the Comunidad de Madrid (ALIBIRD P2009/AGR-1469 Project).
Requena, Teresa, Moreno-Arribas, M. Victoria, Martínez-Cuesta, M. Carmen, Bartolomé, Begoña, Peláez, Carmen, Molina, Elena, Recio, Isidra   +6 more
openaire   +2 more sources

Impact of Production Process and Gastrointestinal Digestion of Liquid Dairy Products on the Characterization and Transport Capacity of Bovine Milk Exosomes

Shipin gongye ke-ji
In order to compare the differences in typical characterization of bovine milk exosomes between raw milk and liquid dairy products processed by different processing technologies, and to investigate the effects of production process and gastrointestinal ...
Xiyao XU, Longyu WAN, Bo QU, Feng ZHAO
doaj   +1 more source

Continuous Molecular Monitoring Using Electrochemical Aptamer‐Based Sensors: Remaining Challenges for Long‐Term In Vivo Deployment

Advanced Science, EarlyView.
Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley   +1 more source