Results 31 to 40 of about 1,401,410 (172)

High-Throughput Sequencing Reveals CXCR4 and IGF1 Behave Different Roles in Weightlessness Osteoporosis

Stem Cells International, 2022
Objective. This study is aimed at screening the differential expression profiles of mRNA under weightlessness osteoporosis through high-throughput sequencing technology, as well as investigating the pathogenesis of weightlessness osteoporosis at the ...
Dong Wang, Weihang Li, Ziyi Ding, Quan Shi, Shilei Zhang, Zhuoru Zhang, Zhibin Liu, Xiaocheng Wang, Ming Yan   +8 more
doaj   +1 more source

Effects of Simulated Weightlessness on Metabolizing Enzymes and Pharmacokinetics of Folic Acid in SD Rats.

Biological and Pharmaceutical Bulletin, 2021
Folic acid (FA) affect human physiology and drug metabolism. Up to now, the effect of microgravity on the pharmacokinetics of FA remains unclear.
Yang Zhang, Jun Zhao, J. Jing, Ruitao Zhang, Xuejiao Zhou, Jianyi Gao, Jiaping Wang, Yongzhi Li, Xueying Liu, Qingwei Wang   +9 more
semanticscholar   +1 more source

Protective effects of ginsenosides Rg1 and Rb1 against cognitive impairment induced by simulated microgravity in rats

Frontiers in Pharmacology, 2023
Microgravity experienced during space flight is known to exert several negative effects on the learning ability and memory of astronauts. Few effective strategies are currently available to counteract these effects.
Ning Jiang, Jingwei Lv, Yiwen Zhang, Xinran Sun, Caihong Yao, Qiong Wang, Qinghu He, Xinmin Liu, Xinmin Liu   +8 more
doaj   +1 more source

Research on the Specificity of Electrophysiological Signals of Human Acupoints Based on the 90-Day Simulated Weightlessness Experiment on the Ground

IEEE transactions on neural systems and rehabilitation engineering, 2021
Acupoint specificity for diseases has consistently been the focus of acupuncture research owing to its excellent prospects for clinical diagnosis and treatment. However, the specificity of cardiovascular and sleep functions in terms of electrical signals
Yun Wang, Zhiqi Fan, Mixia Wang, Juntao Liu, Shengwei Xu, Zeying Lu, Hao Wang, Yilin Song, Yiding Wang, Lina Qu, Yinghui Li, Xinxia Cai   +11 more
semanticscholar   +1 more source

Oral absorption and drug interaction kinetics of moxifloxacin in an animal model of weightlessness

Scientific Reports, 2021
To investigate the effect of simulated weightlessness on the pharmacokinetics of orally administered moxifloxacin and the antacid Maalox or the antidiarrheal Pepto-Bismol using a tail-suspended (TS) rat model of microgravity.
Dong Liang, Jing Ma, Bo Wei
doaj   +1 more source

Biofabrication of in situ Self Assembled 3D Cell Cultures in a Weightlessness Environment Generated using Magnetic Levitation

Scientific Reports, 2018
Magnetic levitation though negative magnetophoresis is a novel technology to simulate weightlessness and has recently found applications in material and biological sciences.
Muge Anil-Inevi, Sena Yaman, Ahu Arslan Yildiz, Gulistan Mese, Ozden Yalcin-Ozuysal, H. Cumhur Tekin, Engin Ozcivici   +6 more
doaj   +1 more source

Artificial gravity as a countermeasure for mitigating physiological deconditioning during long-duration space missions

Frontiers in Systems Neuroscience, 2015
In spite of the experience gained in human space flight since Yuri Gagarin’s historical flight in 1961, there has yet to be identified a completely effective countermeasure for mitigating the effects of weightlessness on humans. Were astronauts to embark
Gilles eClement, Angie eBukley, William ePaloski   +2 more
doaj   +1 more source

Microgravity and Musculoskeletal Health: What Strategies Should Be Used for a Great Challenge?

Life, 2023
Space colonization represents the most insidious challenge for mankind, as numerous obstacles affect the success of space missions. Specifically, the absence of gravitational forces leads to systemic physiological alterations, with particular emphasis on
Roberto Bonanni, Ida Cariati, Mario Marini, Umberto Tarantino, Virginia Tancredi   +4 more
doaj   +1 more source

Simulated Microgravity Using a Rotary Culture System Compromises the In Vitro Development of Mouse Preantral Follicles. [PDF]

PLoS ONE, 2016
Growing cells in simulated weightlessness condition might be a highly promising new technique to maintain or generate tissue constructs in a scaffold-free manner.
Shen Zhang, Dahan Zheng, Yonggen Wu, Wei Lin, Zaichong Chen, Luhe Meng, Jun Liu, Ying Zhou   +7 more
doaj   +1 more source

The influence of simulated weightlessness on the composition and function of gut microbiota and bile acid metabolism products.

Life sciences and space research
The aim of this study was to investigate the effects of simulated weightlessness on gut microbiota, bile acid metabolism, and inflammatory cytokines compared to the control group.
Min Wang, Sheng Chen, Changqing Zhong, Lei Liu, Guodong Wang, Xin Huang, Xiaoman Yang, Heming Yang, Lianyong Li   +8 more
semanticscholar   +1 more source