Results 61 to 70 of about 2,480,753 (297)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

An assessment of the effects of simulation training on management of postpartum hemorrhage: short- and long-term impact on knowledge retention, skills and teamwork in the Democratic Republic of Congo

BMC Medical Education
Background Major obstetric hemorrhage is the leading direct cause of maternal mortality throughout the world. To prevent maternal mortality, it is crucial to raise concerns regarding the knowledge and skill levels of the healthcare providers. The purpose
Jean Paul Buhendwa Cikwanine, Denis Mukwege, Justin Mongwa, Emile Mapatano shalamba, Raha Maroyi, Jonathan Tunangoya Yoyu, Ludovic Martin   +6 more
doaj   +1 more source

COVID-19 pandemic preparation: using simulation for systems-based learning to prepare the largest healthcare workforce and system in Canada

Advances in Simulation, 2020
Healthcare resources have been strained to previously unforeseeable limits as a result of the COVID-19 pandemic of 2020. This has prompted the emergence of critical just-in-time COVID-19 education, including rapid simulation preparedness, evaluation and ...
Mirette Dubé, Alyshah Kaba, Theresa Cronin, Sue Barnes, Tara Fuselli, Vincent Grant   +5 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

The chiral Hall effect in canted ferromagnets and antiferromagnets

Communications Physics, 2021
The Hall effect is about the generation of a transverse voltage when a longitudinal current is applied and many mechanisms can lead to Hall effect in magnetic material. Here, the authors report a chiral Hall effect that is proportional to the vector spin
Jonathan Kipp, Kartik Samanta, Fabian R. Lux, Maximilian Merte, Dongwook Go, Jan-Philipp Hanke, Matthias Redies, Frank Freimuth, Stefan Blügel, Marjana Ležaić, Yuriy Mokrousov   +10 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Research and Realization of the Simulation Test System for Train Control On-board Equipment

机车电传动, 2017
Aiming at the requirement of simulation test to train control on-board equipment, the overall technical scheme and the realization method of the simulation test system for train control on-board equipment were presented by analyzing the running ...
Research and Realization of the Simulation Test System for Train Control On-board Equipment
doaj  

A Fast Algorithm for Solving a Class of the Linear Complementarity Problem in a Finite Number of Steps

Abstract and Applied Analysis, 2020
The linear complementarity problem is receiving a lot of attention and has been studied extensively. Recently, El foutayeni et al. have contributed many works that aim to solve this mysterious problem.
Yamna Achik, Asmaa Idmbarek, Hajar Nafia, Imane Agmour, Youssef El foutayeni   +4 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Simulation Tools [PDF]

, 2018
Simulation can enable several developments in the field of intelligent vehicles. This chapter is divided into three main subsections. The first one deals with driving simulators. The continuous improvement of hardware performance is a well-known fact that is allowing the development of more complex driving simulators.
Brazalez, Alfonso, Matey, Luis, Nuñez, Borja, Paul, Ana, Sánchez-Medina, Javier J., Arnay, Rafael, Artunedo, Antonio, Campos-Cordobés, Sergio, Villagra, Jorge, López, Antonio M., Vázquez, David, Villalonga, Gabriel   +11 more
openaire   +2 more sources