Results 61 to 70 of about 1,873,107 (281)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Approximating trigonometric functions by using exponential inequalities

Journal of Inequalities and Applications, 2019
In this paper, some exponential inequalities are derived from the inequalities containing trigonometric functions. Numerical examples show that one can achieve much tighter bounds than those of prevailing methods, which are presented by Cusa, Huygens ...
Xiao-Diao Chen, Junyi Ma, Yixin Li
doaj   +1 more source

Disruptions to shared mental models from poor quality of service in collaborative virtual environments

Scientific Reports, 2021
Collaborative virtual environments are being used in various applications ranging from online games to complex team training scenarios. The key to the success of such environments is the ability of the participants to form a shared mental model of the ...
Nicholas Milef, Adam Ryason, Di Qi, Samuel O. Alfred, Cullen D. Jackson, Suvranu De   +5 more
doaj   +1 more source

Diffusion of Confidential Information on Networks [PDF]

, 2011
This is a natural generalization of the previous work by Dan, "Modeling and Simulation of Diffusion Phenomena on Social Networks," to appear in The proceedings of 2011 Third International Conference on Computer Modeling and Simulation.
Dan, Yuya
core  

Simulation modeling of the sensitivity analysis of differential effects of the intrinsic growth rate of a fish population: its implication for the selection of a local minimum [PDF]

, 2018
The vulnerability of the differential effects of the intrinsic growth rates of the fish population on the uncertainty analysis can only be controlled by using the mathematical technique of a sensitivity analysis that is called a local minimum selection ...
C, N. E. (Nwachukwu), N, E. E. (Ekaka-a), U, A. J. (Atsu)   +2 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A novel Bayesian generative approach for estimating tumor dynamics from published studies

CPT: Pharmacometrics & Systems Pharmacology
Tumor growth inhibition (TGI) modeling attempts to describe the time course changes in tumor size for patients undergoing cancer therapy. TGI models present several advantages over traditional exposure–response models that are based explicitly on ...
Arya Pourzanjani, Saurabh Modi, Jamie Connarn, Xinwen Zhang, Vijay Upreti, Chih‐Wei Lin, Khamir Mehta   +6 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

NK Simulation Modeling

, 2016
Launched and developed primarily by Kauffman from the end of sixties, NK simulation modelling candidates for capturing networks dynamics. Grounded in reference to biological networks, it has aroused a grate and durable interest in economics and management sciences too. This methodology is split into a version focused on studying proper Boolean networks
openaire   +1 more source

The role of primitive part modelling within an integrative simulation environment [PDF]

, 2003
The component-based modeling approach to the simulation of HVAC systems has been in used for many years. The approach not only supports plant simulation but also allows the integration of the building and plant domains.
Chow, T.T., Clarke, J.A., Song, C.L.
core