Results 41 to 50 of about 37,158 (207)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Visual and Visual‐Inertial SLAM Based on Enhanced Deep Learning Features and Motion Smoothness Constraints

open access: yesAdvanced Intelligent Systems
It is highly challenging to ensure accuracy and robustness of simultaneous localization and mapping (SLAM) algorithms with rapid camera movements and drastic viewpoint changes. In these scenarios, feature extraction, feature matching, and tracking become
Maosheng Jiang   +3 more
doaj   +1 more source

VA-LOAM: Visual Assist LiDAR Odometry and Mapping for Accurate Autonomous Navigation

open access: yesSensors
In this study, we enhanced odometry performance by integrating vision sensors with LiDAR sensors, which exhibit contrasting characteristics. Vision sensors provide extensive environmental information but are limited in precise distance measurement ...
Tae-Ki Jung, Gyu-In Jee
doaj   +1 more source

Simultaneous Indoor Pedestrian Localization and House Mapping Based on Inertial Measurement Unit and Bluetooth Low-Energy Beacon Data

open access: yesSensors, 2020
Indoor location estimation is crucial to provide context-based assistance in home environments. In this study, a method for simultaneous indoor pedestrian localization and house mapping is proposed and evaluated. The method fuses a person’s movement data
Jesus D. Ceron   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Tightly-Coupled Monocular Visual-Odometric SLAM Using Wheels and a MEMS Gyroscope

open access: yesIEEE Access, 2019
In this paper, we present a novel tightly coupled probabilistic monocular visual-odometric simultaneous localization and mapping (VOSLAM) algorithm using wheels and a MEMS gyroscope, which can provide accurate, robust, and long-term localization for ...
Meixiang Quan   +3 more
doaj   +1 more source

BatSLAM: Simultaneous localization and mapping using biomimetic sonar. [PDF]

open access: yesPLoS ONE, 2013
We propose to combine a biomimetic navigation model which solves a simultaneous localization and mapping task with a biomimetic sonar mounted on a mobile robot to address two related questions.
Jan Steckel, Herbert Peremans
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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