Results 91 to 100 of about 50,616 (252)

Immune Consequences of Metabolic Syndrome and Its Treatment: A Cytokine Perspective

Immunology, EarlyView.
Peripheral blood mononuclear cells (PBMCs) from individuals with metabolic syndrome (MetS) who were not using glucose‐and/or lipid lowering medication (GLLM) exhibited a broader cytokine production profile after in vitro antigen‐specific stimulation than PBMCs from individuals with MetS using such medications and from healthy donors.
Isabela Ghetti Macedo Isaac, Carolina do Prado Servian, Fernanda de Oliveira Feitosa de Castro, João Lucas Lima Calandrini de Azevedo, Ronaldo Moraes Preto, Miriam Leandro Dorta, Daniela Espíndola Antunes, Simone Gonçalves Fonseca   +7 more
wiley   +1 more source

The possible ameliorating effect of platelet-rich plasma on simvastatin induced skeletal myopathy in adult male albino rats. A histological study.

The Egyptian Journal of Histology
Introduction: Simvastatin becomes one of the most administered medications in cases of hyperlipidemia. Simvastatin is strongly associated with skeletal myopathy when compared to other statins.
Nesrine elhomosany, Heba Ibrahim, Abeer Ahmed   +2 more
doaj   +1 more source

Protektive Effekte von Simvastatin beim Endotoxinschock [PDF]

, 2014
Simvastatin wurde wegen seiner pleiotropen Effekte mehrfach in Studien in der Sepsis eingesetzt. Ziel der Arbeit war es dessen Effekte in einem Endotoxinschockmodell in Ratten zu untersuchen.
Schnell, Martin Gustav Otto
core   +1 more source

Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications

Journal of Periodontal Research, EarlyView.
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu, Yuan Chen, Mario Romandini, Håvard Jostein Haugen, Sašo Ivanovski   +4 more
wiley   +1 more source

Sleep characteristics and self‐reported sleep quality in the oldest‐old: Results from a prospective longitudinal cohort study

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Little is known about the correlation between subjective perception and objective measures of sleep quality in particular in the oldest‐old. The aim of this study was to perform longitudinal home sleep monitoring in this age group, and to correlate results with self‐reported sleep quality.
Hugo Saner, Kevin Möri, Narayan Schütz, Philipp Buluschek, Tobias Nef   +4 more
wiley   +1 more source

Charge effect of a liposomal delivery system encapsulating simvastatin to treat experimental ischemic stroke in rats

, 2016
Mireia Campos-Martorell,1 Mary Cano-Sarabia,2 Alba Simats,1 Mar Hernández-Guillamon,1 Anna Rosell,1 Daniel Maspoch,2,3 Joan Montaner1,4 1Neurovascular Research Laboratory, Institut de Recerca Vall d’Hebron, Universitat Autònoma de ...
Cano-Sarabia M, Campos-Martorell M, Rosell A, Simats A, Montaner J, Hernández-Guillamon M, Maspoch D   +6 more
core  

Pleiotropic effects of ezetimibe/simvastatin vs. high dose simvastatin [PDF]

, 2012
Background: In the setting of stable coronary artery disease (CAD), it is not known if the pleiotropic effects of cholesterol reduction differ between combined ezetimibe/simvastatin and high-dose simvastatin alone.
James A. de Lemos, Serrano Jr., Carlos V., Lemos, James A. de, de Lemos, James A., Herlon S. Martins, Souza, Heraldo Possolo de, Carlos V. Serrano, Maranhão, Raul Cavalcante, Fernandes, Juliano L., Serrano, Carlos V., Antonio Eduardo P. Pesaro, Maranhão, Raul C., Alexandre B. Cavalcanti, Pesaro, Antonio Eduardo P., José C. Nicolau, Nicolau, Jose C., Campos, Alexandre H., Cavalcanti, Alexandre B., Heraldo P. Souza, Alexandre H. Campos, Martins, Herlon S., Raul C. Maranhão, Souza, Heraldo P., Juliano L. Fernandes   +23 more
core   +1 more source

The comparison of simvastatin and atorvastatin efficacy in lowering lipid profile and apolipoprotein-b of diabetic dyslipidemia patient [PDF]

, 2013
HMG-CoA reductase inhibitors (Statins) are effective lipid-lowering drugs for the treatment of dyslipidemia patients with type 2diabetes mellitus (T2DM).
Sony Wibisono, Budi Suprapti, Nur Palestin Ayumuyas, Debra Dorotea   +3 more
core   +2 more sources

Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia [PDF]

, 2002
ObjectivesThe purpose of this study was to assess the efficacy and safety of ezetimibe administered with simvastatin in patients with primary hypercholesterolemia.BackgroundDespite the availability of statins, many patients do not achieve lipid targets ...
Suresh, Ramachandran, Davidson, Michael H, Sun, Steven, Lipka, Leslie J, LeBeaut, Alexandre P, Veltri, Enrico P, Bettis, Robert, Melani, Lorenzo, McGarry, Thomas   +8 more
core   +1 more source

Mystery and misery of locally‐delivered drug therapy in periodontics. Historical concepts and current state

Periodontology 2000, EarlyView.
Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley   +1 more source