Journal of the American Geriatrics Society, EarlyView.ABSTRACT Background Evidence supporting the use of statins for primary prevention of cardiovascular disease (CVD) in individuals aged ≥ 80 years remains limited. This study aimed to evaluate the long‐term clinical benefits and safety of statins for primary prevention in patients aged 80 years and older.
Ophir Lavon, Wafaa Hamodi, Sameer Kassem
wiley +1 more source
Preparation and Characterization of Simvastatin Loaded PLGA Microparticles forTissue Engineering Applications [PDF]
, 2012 Simvastatin has been reported to promote osteoblastic activity and inhibit osteoclastic activity. The successful use of simvastatin to promote in vivo bone formation depends on the local concentration, and there have been continuous efforts to find an ...
Ciardelli, Gianluca +5 more
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Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells [PDF]
, 2017 Zheyong Liang +14 more
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Conducting Medication Reviews: A Comparative Study Between ChatGPT‐4 and Healthcare Professionals
Journal of the American Geriatrics Society, EarlyView.ABSTRACT Background The increasing prevalence of patients with hyperpolypharmacy (> 10 medications) has made medication reviews increasingly complex. ChatGPT‐4‐Turbo (ChatGPT), a large language model, has demonstrated potential in healthcare applications and could potentially support medication reviews.
Simone M. K. ten Hoope +5 more
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Respiratory Research, 2009 Background Simvastatin has been shown to ameliorate pulmonary hypertension by several mechanisms in experimental animal models. In this study, we hypothesized that the major benefits of simvastatin in pulmonary hypertension occur via the heme oxygenase-1
Lee Yung-Chie +6 more
doaj +1 more source
Effects of adjunctive eslicarbazepine acetate on serum lipids in patients with partial-onset seizures: Impact of concomitant statins and enzyme-inducing antiepileptic drugs. [PDF]
, 2018 PURPOSE: To evaluate the effects of eslicarbazepine acetate (ESL) on lipid metabolism and to determine whether reduced statin exposure during ESL therapy has clinical consequences. SUBJECTS AND METHODS: We conducted a post-hoc analysis of pooled data for
Ben-Menachem, Elinor +11 more
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Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications
Journal of Periodontal Research, EarlyView.Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu +4 more
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e0298 Intensive cholesterol lowering with simvastatin improves outcomes of percutaneous coronary intervention in patients with acute coronary syndrome [PDF]
, 2010 F. Xianghua +7 more
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Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Little is known about the correlation between subjective perception and objective measures of sleep quality in particular in the oldest‐old. The aim of this study was to perform longitudinal home sleep monitoring in this age group, and to correlate results with self‐reported sleep quality.
Hugo Saner +4 more
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