Results 101 to 110 of about 50,616 (252)

Simvastatin ameliorates established pulmonary hypertension through a heme oxygenase-1 dependent pathway in rats

open access: yesRespiratory Research, 2009
Background Simvastatin has been shown to ameliorate pulmonary hypertension by several mechanisms in experimental animal models. In this study, we hypothesized that the major benefits of simvastatin in pulmonary hypertension occur via the heme oxygenase-1
Lee Yung-Chie   +6 more
doaj   +1 more source

Simvastatin dengan Senyawa Turunan Β-Siklodextrin [PDF]

open access: yes
This study aims to determine the profile of the inclusion complex formed between simvastatin and β-cyclodextrin and its derivatives. To determine the level of stability and determine the solubility level of the inclusion complex formed between ...
Cristy, Devina Wahyu Astaning   +2 more
core   +1 more source

Engineered surface strategies to manage dental implant‐related infections

open access: yesPeriodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza   +7 more
wiley   +1 more source

Behavioral interactions of simvastatin and fluoxetine in tests of anxiety and depression

open access: yes, 2012
Tainaê Santos,1 Monaliza Marizete Baungratz,1 Suellen Priscila Haskel,2 Daniela Delwing de Lima,3 Júlia Niehues da Cruz,4 Débora Delwing Dal Magro,5 José Geraldo Pereira da Cruz51Department of Medicine ...
Baungratz MM   +6 more
core  

Bone biology in aging periodontal and peri‐implant tissues

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Periodontal disease is an age‐related chronic inflammatory condition leading to tooth loss. Dental implants are an option for replacement of lost teeth in older adults. However, age‐related changes to alveolar bone may have pathological implications for its role in supporting the dentition and dental implants.
Dalia Rasheed Issa   +2 more
wiley   +1 more source

Understanding exosomes in regenerative dentistry

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad   +2 more
wiley   +1 more source

Rapid disintegrating tablets of simvastatin dispersions in polyoxyethylene–polypropylene block copolymer for maximized disintegration and dissolution

open access: yes, 2016
Gehan F Balata,1,2 Ahmad S Zidan,2 Mohamad AS Abourehab,1,3 Ebtessam A Essa4 1Department of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia; 2Department of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig,
Balata GF   +3 more
core  

Simvastatin treatment reduces caveolar density.

open access: yes, 2014
A. Representative membrane from control and simvastatin-treated cardiac myocytes. Arrows indicate caveolae. Scale bar represents 200 nm. B. Simvastatin treatment reduced the mean density of caveolae measured in ≈330 µm of membrane (n = 9 myocytes from 3 ...
Shailesh R. Agarwal (587629)   +5 more
core   +1 more source

Effects of non‐surgical periodontal therapy on intrabony periodontal defects at different re‐evaluation time points: A systematic review of randomized controlled trials and clinical recommendations

open access: yesPeriodontology 2000, EarlyView.
Abstract Objective The aim of this systematic review and meta‐analysis was to evaluate the longitudinal temporal pattern of periodontal probing depth (PPD) reduction in intrabony periodontal defects following non‐surgical periodontal therapy (NSPT), both as a monotherapy and with adjunctive locally delivered pharmacological agents.
Luca Ramaglia   +4 more
wiley   +1 more source

Simvastatin nanoparticles attenuated intestinal ischemia/reperfusion injury by downregulating BMP4/COX-2 pathway in rats

open access: yes, 2017
Fei Tong,1 Bo Dong,1 Rongkui Chai,1 Ke Tong,2,3 Yini Wang,4 Shipiao Chen,1 Xinmei Zhou,1 Daojun Liu5 1Department of Pathology and Pathophysiology, Provincial Key Discipline of Pharmacology, Jiaxing University Medical College, Jiaxing, Zhejiang, 2College
Chai R   +7 more
core  

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