Results 121 to 130 of about 46,710 (255)

Effect of repeated hot water immersion on cognitive performance, cerebrovascular function, sleep and biomarkers of neurodegeneration in older adults

Experimental Physiology, EarlyView.
Abstract Ageing is associated with cognitive decline and increased risk of developing neurodegenerative disease. Repeated passive heating, using hot water immersion (HWI), may improve cognitive performance via improved cerebral oxygenation, but this is yet to be examined in older adults.
Daniel D. Piccolo, Jo Corbett, Joseph T. Costello, Thomas B. Williams, Thomas J. James, Janis K. Shute, Mohammad G. A. Alnajjar, Luke C. Hudson, Poppy A. Marsh, Veronika Praskacova, Harry S. Mayes, Michael Tipton, Maria Perissiou, Melitta A. McNarry, Kelly A. Mackintosh, Zoe L. Saynor, Anthony I. Shepherd   +16 more
wiley   +1 more source

Solubility enhancement of simvastatin by arginine: thermodynamics, solute–solvent interactions, and spectral analysis

, 2016
MMR Meor Mohd Affandi,1,2 Minaketan Tripathy,1,3 Syed Adnan Ali Shah,3,4 ABA Majeed1,3 1Laboratory of Fundamental Pharmaceutics, Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Bandar Puncak Alam, Selangor, Malaysia; 2DDH Core, Universiti ...
Shah SAA, Tripathy M, Meor Mohd Affandi MMR, Majeed ABA   +3 more
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Simvastatin Encapsulation in Alginate-Based Microspheres

, 2016
Despite the great success of hip implant surgeries, wear particle-induced implant aseptic loosening still limits the implant longevity. Simvastatin, an FDA-approved cholesterol lowering statin, is a promising drug candidate for the treatment of implant ...
Parsian, Ava
core   +1 more source

Effect of repeated hot water immersion on muscle strength, power, function and physical activity in healthy older adults: A randomised crossover trial

Experimental Physiology, EarlyView.
Abstract Ageing leads to an increased prevalence of sarcopenia and frailty, characterised by progressive declines in muscle strength, power and function and reduced physical activity. Hot water immersion (HWI) could potentially improve muscle function, but this is yet to be explored in older adults.
Daniel D. Piccolo, Jo Corbett, Timothy A. Exell, Joseph M. Moore, Amy Wright, Mohammad G. A. Alnajjar, Luke C. Hudson, Poppy A. Marsh, Veronika Praskacova, Melitta A. McNarry, Kelly A. Mackintosh, Zoe L. Saynor, Anthony I. Shepherd   +12 more
wiley   +1 more source

Simvastatin attenuates radiation-induced salivary gland dysfunction in mice

, 2016
Liping Xu,* Xi Yang,* Jiayan Chen, Xiaolin Ge, Qin Qin, Hongcheng Zhu, Chi Zhang, Xinchen Sun Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China *These authors ...
Xu L, Yang X, Qin Q, Chen J, Ge X, Zhu H, Zhang C, Sun X   +7 more
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Simvastatin treatment in db/db mice.

, 2012
A–B: Dyslipid metabolism was significantly improved after treatment with Simvastatin in (A) serum cholesterol and (B) triglycerides. C: The levels of glucose were not changed. D: The levels of albuminuria were also remarked decreased in db/db mice.
Hui-Mei Chen (137029), Zhi-Hong Liu (137039), Chun-Xia Zheng (137033), Yong-Chun Ge (137037), Qing Gao (109581)   +4 more
core   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Impacts of Pharmacokinetic Gene Polymorphisms on Steady‐State Plasma Concentrations of Simvastatin in Thai Population

Clinical and Translational Science
Simvastatin, an HMG‐CoA reductase inhibitor, is widely used for hypercholesterolemia but may cause myotoxicity linked to its plasma concentration. Pharmacokinetic gene polymorphisms influence inter‐individual variability in simvastatin exposure.
Sayanit Tipnoppanon, Udomsak Udomnilobol, Sarawut Siwamogsatham, Yongkasem Vorasettakarnkij, Chonlaphat Sukasem, Thomayant Prueksaritanont, Pajaree Chariyavilaskul, Varalee Yodsurang, Thanate Srimatimanon, Monpat Chamnanphon, Natchaya Vanwong   +10 more
doaj   +1 more source

Effect of simvastatin on MMPs and TIMPs in cigarette smoke-induced rat COPD model

, 2017
Jiawei Sun,1,* Jie Bao,2,* Yanan Shi,3 Bin Zhang,4 Lindong Yuan,5 Junhong Li,1 Lihai Zhang,1 Mo Sun,6 Ling Zhang,2 Wuzhuang Sun1 1Department of Respiratory Medicine, First Hospital of Hebei Medical University, 2Department of Respiratory Medicine, Chest ...
Sun M, Li J, Bao J, Yuan L, Zhang L, Sun W, Zhang B, Sun J, Shi Y   +8 more
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Blood cholesterol levels of hypercholesterolemic rat (Rattus norvegicus) after VCO treatment [PDF]

, 2009
Abstrak. Harini M, Astirin OP. 2009. Kadar kolesterol darah tikus putih (Rattus norvegicus) hiperkolesterolemik setelah perlakuan VCO. Nusantara Bioscience 1: 53-58.
ASTIRIN, OKID PARAMA, HARINI, MARTI
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