Results 121 to 130 of about 50,616 (252)
The Journal of Physiology, EarlyView.Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
Clinical and Translational ScienceSimvastatin, an HMG‐CoA reductase inhibitor, is widely used for hypercholesterolemia but may cause myotoxicity linked to its plasma concentration. Pharmacokinetic gene polymorphisms influence inter‐individual variability in simvastatin exposure.
Sayanit Tipnoppanon +10 more
doaj +1 more source
, 2015 Michelle E John,1 John R Cockcroft,2 Tricia M McKeever,3 William R Coward,1 Dennis J Shale,2 Simon R Johnson,1 Jim G Thornton,4 Timothy W Harrison,1 Alan J Knox,1 Charlotte E Bolton1 1Nottingham Respiratory Research Unit, School of Medicine, University ...
Thornton JG +9 more
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Simvastatin treatment in db/db mice.
, 2012 A–B: Dyslipid metabolism was significantly improved after treatment with Simvastatin in (A) serum cholesterol and (B) triglycerides. C: The levels of glucose were not changed. D: The levels of albuminuria were also remarked decreased in db/db mice.
Hui-Mei Chen (137029) +4 more
core +1 more source
Simvastatin attenuates radiation-induced salivary gland dysfunction in mice
, 2016 Liping Xu,* Xi Yang,* Jiayan Chen, Xiaolin Ge, Qin Qin, Hongcheng Zhu, Chi Zhang, Xinchen Sun Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China *These authors ...
Xu L +7 more
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Blood cholesterol levels of hypercholesterolemic rat (Rattus norvegicus) after VCO treatment [PDF]
, 2009 Abstrak. Harini M, Astirin OP. 2009. Kadar kolesterol darah tikus putih (Rattus norvegicus) hiperkolesterolemik setelah perlakuan VCO. Nusantara Bioscience 1: 53-58.
ASTIRIN, OKID PARAMA, HARINI, MARTI
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Mechanism‐Informed Pharmacotherapy Optimization and Deprescribing: A Redox–Mitochondrial Framework
Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.From cumulative drug burden to mitochondrial stress and functional decline. The graphical abstract summarizes the central concept of the review, illustrating how cumulative pharmacotherapy exposure may contribute to redox–mitochondrial stress and thereby reduce biological and functional resilience.
Boštjan Martinc
wiley +1 more source
Simultaneous estimation of statins like pravastain, atorvastatin and simvastatin in bulk and pharmaceutical dosage form by means of High-Performance Liquid Chromatography [PDF]
, 2013 The aim of this study was to develop and validate a simple, rapid, precise, more accurate, reliable, least time consuming HPLC method for individual as well as simultaneous estimation of pravastatin, atorvastatin and simvastatin in bulk and ...
Mantelingu, K. +4 more
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Natural History of Recurrent Acute Pancreatitis: Implications for Interventional Trial Design
Alimentary Pharmacology &Therapeutics, Volume 64, Issue 7, Page 976-984, October 2026.In this nationwide cohort of 6894 patients with recurrent acute pancreatitis, recurrence risk increased progressively with each episode and occurred most frequently within the first year. Successive episodes were separated by shorter intervals, indicating an accelerating disease course and highlighting the importance of early preventive interventions ...
Søren S. Olesen +7 more
wiley +1 more source
, 2015 Yin-Chih Fu,1–4 Yan-Hsiung Wang,1,5 Chung-Hwan Chen,1,3,4 Chih-Kuang Wang,1,6 Gwo-Jaw Wang,1,3,4 Mei-Ling Ho1,3,7,8 1Orthopaedic Research Center, 2Graduate Institute of Medicine, 3Department of Orthopaedics, 4Department of Orthopaedics, College of ...
Wang GJ +5 more
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