Results 141 to 150 of about 50,616 (252)
The effect of simvastatin on the gap junction function of hepatocellular carcinoma cells
Zhongguo aizheng zazhi, 2014 Background and purpose: It has been reported that gap junctional (GJ) function was significantly decreased in hepatocellular carcinoma (HCC) tissues and cell lines.
汪灵芝 +3 more
doaj
Pharmacoepidemiology and Drug Safety, Volume 35, Issue 9, September 2026.ABSTRACT Background In pharmacoepidemiologic research, correct assignment of the length of single dispensation is critical to build treatment episodes. The parametric reverse waiting time distribution (rWTD) is a particularly attractive data‐driven method to estimate dispensation lengths.
Mette Reilev +8 more
wiley +1 more source
Linchuang shenzangbing zazhi, 2018 Objective To explore the effect of different statins and EZETIMIBE/SIMVASTATIN on cardiovascular disease in patients with chronic kidney disease(CKD). Methods This study was a prospective study design and selected 503 cases of 3-5 phase CKD patients. The
ZHANG Xue-qing +3 more
doaj
Precision Medical Sciences, Volume 15, Issue 3, Page 227-237, September 2026.This study conducted a systematic review and meta‐analysis of randomized controlled trials (RCTs) to investigate whether acupuncture treatment is more beneficial than Western medicine treatment for patients with nonalcoholic fatty liver disease. The results showed that acupuncture was significantly superior to Western medicine in terms of clinical ...
Bin Yu +8 more
wiley +1 more source
Protein Science, Volume 35, Issue 9, September 2026.Abstract The Lyme disease pathogen Borrelia burgdorferi contains a highly reduced genome lacking many primary metabolic pathways. However, B. burgdorferi retains the mevalonate pathway that synthesizes isopentenyl pyrophosphate (IPP), the precursor to the peptidoglycan carrier lipid.
Isaac A. Paddy +7 more
wiley +1 more source
Acta Ophthalmologica, Volume 104, Issue 6, Page e630-e647, September 2026.Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source
Clinical and Translational Science, Volume 19, Issue 9, September 2026.ABSTRACT Pairwise drug–drug interaction databases flag co‐prescribed pairs, but they under‐weight multi‐drug combinations that drive adverse drug events in older adults. We studied that gap in Virginia All‐Payer Claims Database records (2016–2019) for adults aged 65–114 years with non‐opioid emergency department visits (n = 1182 cases; 16,105 matched ...
R. Jerome Dixon, Elvin T. Price
wiley +1 more source
Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk
International Endodontic Journal, Volume 59, Issue 9, Page 1743-1759, September 2026.ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar +4 more
wiley +1 more source
A transcriptomics-based computational drug repurposing pipeline identifies simvastatin and primaquine as therapeutics for endometriosis. [PDF]
iScienceOskotsky TT +15 more
europepmc +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 17, September 2026.ABSTRACT Sepsis, a life‐threatening condition characterized by systemic inflammation and immune dysregulation, remains a major cause of mortality worldwide. Here, we identify a synthetic sulfonamide intermediate, 1‐[5‐(2‐fluorophenyl)furan‐2‐yl]‐N‐(4‐methylbenzyl)methanamine (FMM), as a host‐directed therapeutic candidate that enhances neutrophil ...
Ji Ye Park +10 more
wiley +1 more source