Results 151 to 160 of about 46,710 (255)
Programmed Cell Death in Chronic Rhinosinusitis
Clinical and Translational Allergy, Volume 16, Issue 6, June 2026.ABSTRACT Chronic rhinosinusitis (CRS) is a prevalent upper respiratory condition characterized by a multifaceted etiology involving various cellular and molecular processes. In recent years, researchers have increasingly recognized the significance of different forms of programmed cell death (PCD), such as apoptosis and pyroptosis, in the pathological ...
Xingchen Liu +5 more
wiley +1 more source
Linchuang shenzangbing zazhi, 2018 Objective To explore the effect of different statins and EZETIMIBE/SIMVASTATIN on cardiovascular disease in patients with chronic kidney disease(CKD). Methods This study was a prospective study design and selected 503 cases of 3-5 phase CKD patients. The
ZHANG Xue-qing +3 more
doaj
Comprehensive Physiology, Volume 16, Issue 3, June 2026.This review summarizes how extracellular vesicles from diverse pulmonary and extrapulmonary sources contribute to endothelial dysfunction in ARDS and evaluates emerging endothelial‐targeted therapies for their potential to mitigate EV‐mediated pathogenic mechanisms.
Mohammed Yaman Al Matni +3 more
wiley +1 more source
Pharmacokinetic Drug–Drug Interaction Potential of Oral Anticancer Drugs
Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1614-1627, June 2026.Drug–drug interaction (DDI) management is critical for safe and effective use of oral anticancer drugs (OADs). Our study objectives were to (i) compile clinically relevant pharmacokinetic (PK) DDI mechanisms for OADs and (ii) assess the prevalence of PK potential DDIs (PDDIs) in patients with advanced solid cancers.
Fatimah Alhurayri +10 more
wiley +1 more source
The effect of simvastatin on the gap junction function of hepatocellular carcinoma cells
Zhongguo aizheng zazhi, 2014 Background and purpose: It has been reported that gap junctional (GJ) function was significantly decreased in hepatocellular carcinoma (HCC) tissues and cell lines.
汪灵芝 +3 more
doaj
, 2013 The aim of this study was to develop and validate a simple, rapid, precise, more accurate, reliable, least time consuming HPLC method for individual as well as simultaneous estimation of pravastatin, atorvastatin and simvastatin in bulk and ...
Mantelingu, K. +4 more
core
Epileptic Disorders, Volume 28, Issue 3, Page 855-867, June 2026.Abstract Objectives Antiseizure medications (ASMs) can induce the activity of drug‐metabolizing enzymes and drug transporters, including cytochrome P450 (CYP)2C9 and P‐glycoprotein (P‐gp). Our objective was to comparatively assess the effects of ASMs on exposure to clinical CYP2C9 and P‐gp substrates.
Hagar Cohen +4 more
wiley +1 more source
, 2019 Usama Farghaly Aly,1 Heba A Abou-Taleb,2 Ahmed AH Abdellatif,3,4 Nahla Sameh Tolba21Department of Pharmaceutics, Faculty of Pharmacy, Minia University, EL-Minia, Egypt; 2Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Nahda ...
Farghaly Aly U +3 more
core
Vascular Calcification: Mechanisms, Models, and Therapies
iNew Medicine, Volume 2, Issue 2, June 2026.ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
Molecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.Smith‐Lemli‐Opitz syndrome (SLOS) is an autosomal recessive disorder caused by pathogenic variants in the DHCR7 gene. Based on our observations and a review of the literature, we demonstrate that the NM_001360.2(DHCR7):c.89G>C p.(Gly30Ala) variant is associated with a mild SLOS phenotype.
Júlia Martinková +8 more
wiley +1 more source