Sinapic Acid Co-Amorphous Systems with Amino Acids for Improved Solubility and Antioxidant Activity [PDF]
International Journal of Molecular Sciences, 2023 The objective of this study was to obtain co-amorphous systems of poorly soluble sinapic acid using amino acids as co-formers. In order to assess the probability of the interaction of amino acids, namely, arginine, histidine, lysine, tryptophan, and ...
Ewa Tykarska +2 more
exaly +4 more sources
Effect of Sinapic Acid on Scopolamine-Induced Learning and Memory Impairment in SD Rats [PDF]
Brain Sciences, 2023 The seriousness of the diseases caused by aging have recently gained attention. Alzheimer’s disease (AD), a chronic neurodegenerative disease, accounts for 60–80% of senile dementia cases.
In-Seo Lee +6 more
doaj +4 more sources
Sinapic Acid Controls Inflammation by Suppressing NLRP3 Inflammasome Activation [PDF]
Cells, 2021 A natural phenolic acid compound, sinapic acid (SA), is a cinnamic acid derivative that contains 3,5-dimethoxyl and 4-hydroxyl substitutions in the phenyl ring of cinnamic acid.
Su Ryeon Seo, Seon Sook Kim
exaly +6 more sources
Sinapic acid alleviates inflammatory bowel disease (IBD) through localization of tight junction proteins by direct binding to TAK1 and improves intestinal microbiota [PDF]
Frontiers in Pharmacology, 2023 Introduction: Although sinapic acid is found in various edible plants and has been shown to have anti-inflammatory properties including colitis, its underlying mechanism and effects on the composition of the gut microbiota are largely unknown.
Sehyeon Jang +7 more
doaj +3 more sources
System biology mediated assessment of molecular mechanism for sinapic acid against breast cancer: via network pharmacology and molecular dynamic simulation [PDF]
Scientific Reports, 2023 Sinapic acid is a hydroxycinnamic acid widespread in the plant kingdom, known to be a potent anti-oxidant used for the treatment of cancer, infections, oxidative stress, and inflammation.
Prarambh S. R. Dwivedi, C. S. Shastry
doaj +3 more sources
Sinapic acid accelerates diabetic wound healing by promoting angiogenesis and reducing oxidative stress [PDF]
Scientific ReportsThe incidence of delayed wound healing associated with diabetes is increasing globally. Synthetic drugs for wound management often carry adverse effects, underscoring the need for safer and more effective alternatives. Sinapic acid, a phytochemical found
Rupal Dubey +4 more
doaj +3 more sources
Micro, 2023 Sinapic acid, 3,5-dimethoxyl-4-hydroxycinnamic acid, belonging to the class of hydroxycinnamic acids, shows antioxidant, anti-inflammatory, anticancer, hepatoprotective, cardioprotective, renoprotective, neuroprotective, antidiabetic, anxiolytic, and ...
Stefano Russo +2 more
doaj +3 more sources
Preparation and Characterization of Transethosome Formulation for the Enhanced Delivery of Sinapic Acid. [PDF]
Pharmaceutics, 2023 Sinapic acid (SA) is a bioactive phenolic acid; its diverse properties are its anti-inflammatory, antioxidant, anticancer, and antibacterial activities. The bioactive compound SA is poorly soluble in water.
Bin Jardan YA +3 more
europepmc +5 more sources
Sinapic Acid Ameliorates Acetic Acid-Induced Ulcerative Colitis in Rats by Suppressing Inflammation, Oxidative Stress, and Apoptosis [PDF]
Molecules, 2022 Background: Ulcerative colitis (UC) is a long-term condition which results in inflammation and ulcers of the colon and rectum. The key indications of active disease are abdominal pain and diarrhea mixed with blood.
Ajaz Ahmad +2 more
exaly +3 more sources
Changes in Quality of Cold-Pressed Rapeseed Oil with Sinapic Acid Ester-Gelatin Films during Storage [PDF]
Foods, 2022 In recent years, cold-pressed rapeseed oil (CPRO) has become an attractive health-beneficial product and a promising alternative to olive oil. However, a high level of unsaturated fatty acids renders a CPRO more susceptible to oxidative deterioration ...
Dobrochna Rabiej-Kozioł +2 more
doaj +3 more sources