Sindbis Virus Antibody Seroprevalence in Central Plateau Populations, South Africa [PDF]
Emerging Infectious Diseases, 2022 We report a higher percentage of Sindbis virus-specific IgG in serum from patients attending a rheumatology clinic (18.8%) compared with healthy residents (9.6%) and patients with acute febrile illness (9.4%) in Free State Province, South Africa ...
Nicole Kennedy +4 more
doaj +4 more sources
Involvement of the endocannabinoid system in the inhibition of Sindbis virus replication: a preliminary study [PDF]
Journal of Cannabis Research, 2021 Background Sindbis virus (Alphaviridae) is a plus-strand RNA virus that is dependent on the host cell for replication. Cannabinoid (CB) receptors are found on most human cells, including virally infected cells.
Juan L. Rodriguez +2 more
doaj +4 more sources
Local Circulation of Sindbis Virus in Wild Birds and Horses, the Netherlands, 2021–2022 [PDF]
Emerging Infectious DiseasesWe report Sindbis virus circulation in the Netherlands based on serologic evidence found in 6 resident wild birds and 3 horses (2021–2022). Tested mosquitoes were molecularly negative, and humans were serologically negative.
Kiki Streng +18 more
doaj +2 more sources
Immunogenicity of a DNA-Based Sindbis Replicon Expressing Crimean–Congo Hemorrhagic Fever Virus Nucleoprotein [PDF]
Vaccines, 2021 Crimean–Congo hemorrhagic fever virus (CCHFV) infrequently causes hemorrhagic fever in humans with a case fatality rate of 30%. Currently, there is neither an internationally approved antiviral drug nor a vaccine against the virus.
Thomas Tipih +2 more
doaj +2 more sources
Sindbis virus ts103 has a mutation in glycoprotein E2 that leads to defective assembly of virions [PDF]
, 1989 Sindbis virus mutant ts103 is aberrant in the assembly of virus particles. During virus budding, proper nucleocapsid-glycoprotein interactions fail to occur such that particles containing many nucleocapsids are formed, and the final yield of virus is low.
Chang S. Hahn +4 more
openalex +4 more sources
Sindbis Virus Replication Reduces Dependence on Mitochondrial Metabolism During Infection [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Alphaviruses are single stranded, positive sense RNA viruses that are often transmitted through mosquito vectors. With the increasing spread of mosquito populations throughout the world, these arboviruses represent a significant global health concern ...
Juan L. Rodriguez +5 more
doaj +2 more sources
A new anterograde trans-synaptic tracer based on Sindbis virus [PDF]
Neural Regeneration Research, 2022 Mapping neural circuits is critical for understanding the structure and function of the nervous system. Engineered viruses are a valuable tool for tracing neural circuits.
Xiang-Wei Shi +3 more
doaj +2 more sources
Infectious virus-antibody complexes of sindbis virus [PDF]
Infection and Immunity, 1977 Infectious virus-antibody complexes were formed when Sindbis virus was reacted with antibodies raised against purified viral envelope glycoproteins E1 and E2 as well as against preparations of intact virus. Results from rate zonal centrifugation in sucrose gradients of the complex formed with anti-E1 sera showed this complex to be about the same size ...
Janey Symington +2 more
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Vector Competence of Mosquitoes from Germany for Sindbis Virus [PDF]
Viruses, 2022 Transmission of arthropod-borne viruses (arboviruses) are an emerging global health threat in the last few decades. One important arbovirus family is the Togaviridae, including the species Sindbis virus within the genus Alphavirus.
Stephanie Jansen +8 more
doaj +2 more sources
The pathogenicity and virulence of Sindbis virus [PDF]
VirulenceSindbis virus (SINV), a widely distributed alphavirus, is both a foundational model for viral replication studies and an underrecognized human pathogen.
Kevin J. Sokoloski +3 more
doaj +2 more sources