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Spread of the Sindbis Virus in Fennoscandia

Проблемы особо опасных инфекций, 2023
In the second half of the last century, a persistent focus of the disease caused by Sindbis virus was formed on the territory of Fennoscandia. In different countries, the disease is called Pogosta disease, Ockelbo disease and Karelian fever.
L. V. Rubis
doaj   +3 more sources

Vertical Transmission of Sindbis Virus in Culex Mosquitoes [PDF]

Viruses, 2022
Vertical transmission (VT) is a phenomenon of vector-borne diseases where a pathogen is transferred from an infected arthropod mother to her offspring.
Emma Dahl, Linnea Öborn, Viktoria Sjöberg, Åke Lundkvist, Jenny C. Hesson   +4 more
doaj   +5 more sources

Sindbis Virus Antibody Seroprevalence in Central Plateau Populations, South Africa [PDF]

Emerging Infectious Diseases, 2022
We report a higher percentage of Sindbis virus-specific IgG in serum from patients attending a rheumatology clinic (18.8%) compared with healthy residents (9.6%) and patients with acute febrile illness (9.4%) in Free State Province, South Africa ...
Nicole Kennedy, Dominique Goedhals, Sabeehah Vawda, Philip Armand Bester, Felicity Burt   +4 more
doaj   +2 more sources

A new Defective Helper RNA to produce recombinant Sindbis virus that infects neurons but does not propagate

Frontiers in Neuroanatomy, 2016
Recombinant Sindbis viruses are important tools in neuroscience because they combine rapid and high transgene expression with a capacity to carry large transgenes.
Justus M Kebschull, Justus M Kebschull, Pedro eGarcia da Silva, Anthony M Zador   +3 more
doaj   +2 more sources

Local Circulation of Sindbis Virus in Wild Birds and Horses, the Netherlands, 2021–2022 [PDF]

Emerging Infectious Diseases
We report Sindbis virus circulation in the Netherlands based on serologic evidence found in 6 resident wild birds and 3 horses (2021–2022). Tested mosquitoes were molecularly negative, and humans were serologically negative.
Kiki Streng, Cora M. Holicki, Jenny C. Hesson, Heather Graham, Felicity Chandler, Louie Krol, Rody Blom, Emmanuelle Münger, Anne van der Linden, Constantianus J.M. Koenraadt, Maarten Schrama, Chiara de Bellegarde de Saint Lary, Leo G. Visser, Bas Oude Munnink, Åke Lundkvist, Marion P.G. Koopmans, Henk P. van der Jeugd, Wim H.M. van der Poel, Reina S. Sikkema   +18 more
doaj   +2 more sources

Sindbis Virus Replication Reduces Dependence on Mitochondrial Metabolism During Infection [PDF]

Frontiers in Cellular and Infection Microbiology, 2022
Alphaviruses are single stranded, positive sense RNA viruses that are often transmitted through mosquito vectors. With the increasing spread of mosquito populations throughout the world, these arboviruses represent a significant global health concern ...
Juan L. Rodriguez, Jessica L. Costlow, Max Sheedy, Kelly T. Yoon, Annette M. Gabaldón, J. Jordan Steel   +5 more
doaj   +2 more sources

A new anterograde trans-synaptic tracer based on Sindbis virus [PDF]

Neural Regeneration Research, 2022
Mapping neural circuits is critical for understanding the structure and function of the nervous system. Engineered viruses are a valuable tool for tracing neural circuits.
Xiang-Wei Shi, Fan Jia, Pei Lyu, Fu-Qiang Xu   +3 more
doaj   +2 more sources

Involvement of the endocannabinoid system in the inhibition of Sindbis virus replication: a preliminary study [PDF]

Journal of Cannabis Research, 2021
Background Sindbis virus (Alphaviridae) is a plus-strand RNA virus that is dependent on the host cell for replication. Cannabinoid (CB) receptors are found on most human cells, including virally infected cells.
Juan L. Rodriguez, Joseph A. Lopez, J. Jordan Steel   +2 more
doaj   +2 more sources

Vector Competence of Mosquitoes from Germany for Sindbis Virus [PDF]

Viruses, 2022
Transmission of arthropod-borne viruses (arboviruses) are an emerging global health threat in the last few decades. One important arbovirus family is the Togaviridae, including the species Sindbis virus within the genus Alphavirus.
Stephanie Jansen, Renke Lühken, Michelle Helms, Björn Pluskota, Wolf Peter Pfitzner, Sandra Oerther, Norbert Becker, Jonas Schmidt-Chanasit, Anna Heitmann   +8 more
doaj   +2 more sources

Mitochondrial bioenergetic alterations in mouse neuroblastoma cells infected with Sindbis virus: implications to viral replication and neuronal death.

PLoS ONE, 2012
The metabolic resources crucial for viral replication are provided by the host. Details of the mechanisms by which viruses interact with host metabolism, altering and recruiting high free-energy molecules for their own replication, remain unknown ...
Leandro Silva da Costa, Ana Paula Pereira da Silva, Andrea T Da Poian, Tatiana El-Bacha   +3 more
doaj   +2 more sources