Results 91 to 100 of about 22,215 (261)

Zebrafish as a Versatile Model Organism: From Tanks to Treatment

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava   +9 more
wiley   +1 more source

A Model of Superinfection of Virus-Infected Zebrafish Larvae: Increased Susceptibility to Bacteria Associated With Neutrophil Death

open access: yesFrontiers in Immunology, 2018
Enhanced susceptibility to bacterial infection in the days following an acute virus infection such as flu is a major clinical problem. Mouse models have provided major advances in understanding viral-bacterial superinfections, yet interactions of the ...
Laurent Boucontet   +13 more
doaj   +1 more source

Human infections associated with wild birds. [PDF]

open access: yes, 2008
IntroductionWild birds and especially migratory species can become long-distance vectors for a wide range of microorganisms. The objective of the current paper is to summarize available literature on pathogens causing human disease that have been ...
Bauchinger, Ulf   +4 more
core   +1 more source

Wildlife health risk analysis for conservation translocation: A scalable approach illustrated for wader population restoration

open access: yesConservation Science and Practice, Volume 7, Issue 9, September 2025.
We present a methodological framework for health risk analysis (disease risk analysis) for conservation translocation that enables the process to be scaled and adapted to the project context. We illustrate its application to two wader (shorebird) population restoration projects with differing translocation plans.
Katie M. Beckmann   +15 more
wiley   +1 more source

Semliki Forest viiruse replikaasivalgu nsP1 uurimine [PDF]

open access: yes, 2013
Väitekirja elektrooniline versioon ei sisalda publikatsioone.Semliki Forest viirus kuulub alfaviiruste perekonda sugukonnas Togaviridae. Alfaviirused on olulised patogeenid ning põhjustavad erinevaid vaevusi nii loomadele kui ka inimestele.
Karo-Astover, Liis
core  

Knockdown of piRNA pathway proteins results in enhanced Semliki forest virus production in mosquito cells [PDF]

open access: yes, 2013
The exogenous siRNA pathway is important in restricting arbovirus infection in mosquitoes. Less is known about the role of the PIWI-interacting RNA pathway, or piRNA pathway, in antiviral responses. Viral piRNA-like molecules have recently been described
Donald, Claire L.   +8 more
core   +3 more sources

Proteolytic dissection of Sindbis virus core protein [PDF]

open access: yesJournal of Virology, 1990
Mild trypsin treatment of the Sindbis virus nucleocapsid protein yields a fragment with a molecular mass of approximately 18.5 kilodaltons with its N terminus at residue 105. The fragment, which is stable to further digestion, appears by gel exclusion chromatography to be monomeric.
R K, Strong, S C, Harrison
openaire   +2 more sources

The Function of TER94 of Spodoptera frugiperda 9 Cells When Infected With Invertebrate Iridescent Virus‐6

open access: yesJournal of Basic Microbiology, Volume 65, Issue 8, August 2025.
ABSTRACT The 118 L protein in the envelope of the Invertebrate iridescent virus 6 (IIV6) is responsible for binding to receptors on the surface of permissive cells. We previously elucidated its function by silencing its gene and neutralizing the protein with antibodies.
Kubra Zengin   +3 more
wiley   +1 more source

Implication for alphavirus host-cell entry and assembly indicated by a 3.5Å resolution cryo-EM structure

open access: yesNature Communications, 2018
Alphaviruses are enveloped RNA viruses that contain several human pathogens. Here, the authors use block-based reconstruction method and provide a 3.5 Å cryo-EM structure of sindbis virus that identifies a conserved hydrophobic pocket near the viral ...
Lihong Chen   +12 more
doaj   +1 more source

Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion. [PDF]

open access: yes, 2016
The host responds to virus infection by activating type I interferon (IFN) signaling leading to expression of IFN-stimulated genes (ISGs). Dysregulation of the IFN response results in inflammatory diseases and chronic infections.
Bozzacco, Leonia   +8 more
core  

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