Results 101 to 110 of about 22,347 (256)
Nature Communications, 2018 Alphaviruses are enveloped RNA viruses that contain several human pathogens. Here, the authors use block-based reconstruction method and provide a 3.5 Å cryo-EM structure of sindbis virus that identifies a conserved hydrophobic pocket near the viral ...
Lihong Chen +12 more
doaj +1 more source
Semliki Forest viiruse replikaasivalgu nsP1 uurimine [PDF]
, 2013 Väitekirja elektrooniline versioon ei sisalda publikatsioone.Semliki Forest viirus kuulub alfaviiruste perekonda sugukonnas Togaviridae. Alfaviirused on olulised patogeenid ning põhjustavad erinevaid vaevusi nii loomadele kui ka inimestele.
Karo-Astover, Liis
core
To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes. [PDF]
, 2015 Type I interferon (IFN) is one of the first lines of cellular defense against viral pathogens. As a result of IFN signaling, a wide array of IFN-stimulated gene (ISG) products is upregulated to target different stages of the viral life cycle.
Li, Melody MH +2 more
core +1 more source
Journal of Medical Virology, Volume 97, Issue 10, October 2025.ABSTRACT Dengue virus (DENV) is a major arthropod‐borne pathogen, endemic in over 100 countries and posing global health challenges. While innate immune responses and viral evasion mechanisms have been extensively studied in animal models and mononuclear cells, severe dengue can affect multiple tissues, including the central nervous system (CNS ...
Leandro Mantovani de Castro +10 more
wiley +1 more source
Establishment of a New Real-Time Molecular Assay for the Detection of Babanki Virus in Africa
VirusesBabanki virus is a subtype of the Sindbis virus, a widespread arthropod-borne alphavirus circulating in Eurasia, Africa, and Oceania. Characterized by rashes and arthritis, clinical infections due to Sindbis were mainly reported in Africa, Australia ...
Martin Faye +10 more
doaj +1 more source
Mosquitoborne Sindbis Virus Infection and Long-Term Illness
Emerging Infectious Diseases, 2018 An unexpected human outbreak of the mosquitoborne Sindbis virus occurred in a previously nonendemic area of Sweden. At follow-up, 6–8 months after infection, 39% of patients had chronic arthralgia that affected their daily activities.
Åsa Gylfe +7 more
doaj +1 more source
Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion. [PDF]
, 2016 The host responds to virus infection by activating type I interferon (IFN) signaling leading to expression of IFN-stimulated genes (ISGs). Dysregulation of the IFN response results in inflammatory diseases and chronic infections.
Bozzacco, Leonia +8 more
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Mapping the Habitat Suitability of Culex pipiens in Europe Using Ensemble Bioclimatic Modelling
Journal of Biogeography, Volume 52, Issue 10, October 2025.ABSTRACT Aim Anthropogenic pressure on natural ecosystems has profoundly influenced the dynamics of disease vectors, altering their distribution, phenology, and increasing the risk of vector‐borne diseases. This study aims to investigate the climatic and environmental determinants of Culex pipiens distribution in continental Europe, to inform and ...
Lara Marcolin +5 more
wiley +1 more source
Promising Prodiginins Biological Activities
Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto +6 more
wiley +1 more source
Virology Journal, 2006 Summary We previously reported evidence of West Nile virus (WNV) circulation in UK birds, probably introduced by migratory birds from overseas. We now demonstrate WNV-specific seroconversion in sentinel chickens raised on an English farm.
Dawson Alistair +2 more
doaj +1 more source