Directed evolution generates an oncolytic Sindbis virus with enhanced tumor-killing capacity in osteosarcoma. [PDF]
Sun K +7 more
europepmc +2 more sources
Oncolytic Activity of Sindbis Virus with the Help of GM-CSF in Hepatocellular Carcinoma. [PDF]
Shi X +6 more
europepmc +3 more sources
Subgenomic reporter RNA system for detection of alphavirus infection in mosquitoes. [PDF]
Current methods for detecting real-time alphavirus (Family Togaviridae) infection in mosquitoes require the use of recombinant viruses engineered to express a visibly detectable reporter protein.
J Jordan Steel +4 more
doaj +1 more source
Recombination between Sindbis virus RNAs [PDF]
The genome (49S RNA) of Sindbis virus is a positive-strand RNA of 11.7 kb that consists of two domains. The 5' two-thirds of the RNA codes for the proteins required for replication and transcription of the RNA. The 3' one-third codes for the structural proteins.
B G, Weiss, S, Schlesinger
openaire +3 more sources
Wolbachia elevates host methyltransferase expression to block an RNA virus early during infection. [PDF]
Wolbachia pipientis is an intracellular endosymbiont known to confer host resistance against RNA viruses in insects. However, the causal mechanism underlying this antiviral defense remains poorly understood.
Tamanash Bhattacharya +2 more
doaj +1 more source
Phosphorylated Proteins of Sindbis Virus [PDF]
The capsid and two membrane proteins of Sindbis virus, grown in chicken cells, contain 0.03 to 0.1 mol of phosphate per mol of protein.
M R, Waite +3 more
openaire +2 more sources
Extreme infectious titer variability in individual Aedes aegypti mosquitoes infected with Sindbis virus is associated with both differences in virus population structure and dramatic disparities in specific infectivity. [PDF]
Hodoameda P +3 more
europepmc +3 more sources
In the context of climate change, globalization, and enhanced human traveling, arboviruses continue to represent a threat to public health. West Nile and Usutu viruses are mosquito-borne viruses belonging to the Flaviviridae family (Flavivirus genus) and
Mircea Coroian +9 more
doaj +1 more source
Analysis of the Results of Monitoring Arbovirus Infections in the Volgograd Region in 2019
Relevance. Natural and climatic conditions, a variety of species composition of arthropods and vertebrates determine the possibility of circulation of arboviruses in the Volgograd region. The existence of natural foci of some arbovirus infections and the
A. O. Negodenko +9 more
doaj +1 more source
Infectious virus-antibody complexes of sindbis virus [PDF]
Infectious virus-antibody complexes were formed when Sindbis virus was reacted with antibodies raised against purified viral envelope glycoproteins E1 and E2 as well as against preparations of intact virus. Results from rate zonal centrifugation in sucrose gradients of the complex formed with anti-E1 sera showed this complex to be about the same size ...
J, Symington +2 more
openaire +2 more sources

