Results 31 to 40 of about 22,347 (256)

A new Defective Helper RNA to produce recombinant Sindbis virus that infects neurons but does not propagate

open access: yesFrontiers in Neuroanatomy, 2016
Recombinant Sindbis viruses are important tools in neuroscience because they combine rapid and high transgene expression with a capacity to carry large transgenes.
Justus M Kebschull   +3 more
doaj   +1 more source

Sindbis Virus Maturation

open access: yesJournal of General Virology, 1973
Sindbis virus, a group A arbovirus, is composed of a nucleocapsid and a glycolipoprotein membrane (Pfefferkorn & Hunter, 1963a; Strauss et al. 1968; Schelle & Pfefferkorn, 1969). The membrane protein is specified by the virus genome (Pfefferkorn & Clifford, 1964; Strauss et al.
C E, Pedersen, B P, Sagik
openaire   +2 more sources

A screening for serum markers of arbovirus infections in healthy blood donors from the Volgograd Region

open access: yesИнфекция и иммунитет, 2020
Volgograd region is considered to be endemic West Nile fever (WNF) area due to the established circulation of the West Nile virus (WNV) therein. Some previous independent studies examining samples collected on the territory of the Volgograd region ...
A. О. Negodenkoa   +9 more
doaj   +1 more source

Homologous Interference Induced by Sindbis Virus [PDF]

open access: yesJournal of Virology, 1974
Homologous interference during Sindbis virus infection has been investigated. Prior infection of either chicken embryo fibroblast or BHK 21 cell cultures results in reduced yields of progeny virions of the superinfecting genotype.
R E, Johnston, K, Wan, H R, Bose
openaire   +2 more sources

A survey of mosquito-borne and insect-specific viruses in hospitals and livestock markets in western Kenya.

open access: yesPLoS ONE, 2021
Aedes aegypti and Culex pipiens complex mosquitoes are prolific vectors of arboviruses that are a global threat to human and animal health. Increased globalization and ease of travel have facilitated the worldwide dissemination of these mosquitoes and ...
Tatenda Chiuya   +5 more
doaj   +1 more source

Sindbis virus replicons and Sindbis virus: assembly of chimeras and of particles deficient in virus RNA [PDF]

open access: yesJournal of Virology, 1997
Alphaviruses are a well-characterized group of positive-strand RNA viruses. The identification of cis-acting elements in their genomes and their replication strategy have made them useful as vectors for the expression of heterologous genes. In infected cells, the nonstructural proteins, required for replication and transcription of the viral genes, are
I, Frolov, E, Frolova, S, Schlesinger
openaire   +2 more sources

Glycoprotein is enough for sindbis virus-derived DNA vector to express heterogenous genes

open access: yesVirology Journal, 2011
To investigate the necessity and potential application of structural genes for expressing heterogenous genes from Sindbis virus-derived vector, the DNA-based expression vector pVaXJ was constructed by placing the recombinant genome of sindbis-like virus ...
Fu Juanjuan   +6 more
doaj   +1 more source

Mutation of CD2AP and SH3KBP1 binding motif in alphavirus nsP3 hypervariable domain results in attenuated virus [PDF]

open access: yes, 2018
Infection by Chikungunya virus (CHIKV) of the Old World alphaviruses (family Togaviridae) in humans can cause arthritis and arthralgia. The virus encodes four non-structural proteins (nsP) (nsP1, nsp2, nsP3 and nsP4) that act as subunits of the virus ...
Aquilimeba, Muriel   +13 more
core   +3 more sources

A novel system for the launch of alphavirus RNA synthesis reveals a role for the Imd pathway in arthropod antiviral response.

open access: yesPLoS Pathogens, 2009
Alphaviruses are RNA viruses transmitted between vertebrate hosts by arthropod vectors, primarily mosquitoes. How arthropods counteract alphaviruses or viruses per se is not very well understood.
Vasanthi Avadhanula   +4 more
doaj   +1 more source

Infectious alphavirus production from a simple plasmid transfection+

open access: yesVirology Journal, 2011
We have developed a new method for producing infectious double subgenomic alphaviruses from plasmids transfected into mammalian cells. A double subgenomic Sindbis virus (TE3'2J) was transcribed from a cytomegalovirus PolII promoter, which results in the ...
Olson Ken E   +4 more
doaj   +1 more source

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