Results 41 to 50 of about 22,347 (256)
ZAP's stress granule localization is correlated with its antiviral activity and induced by virus replication. [PDF]
, 2019 Cellular antiviral programs encode molecules capable of targeting multiple steps in the virus lifecycle. Zinc-finger antiviral protein (ZAP) is a central and general regulator of antiviral activity that targets pathogen mRNA stability and translation ...
Jurado, Andrea +6 more
core +2 more sources
PLoS ONE, 2012 The metabolic resources crucial for viral replication are provided by the host. Details of the mechanisms by which viruses interact with host metabolism, altering and recruiting high free-energy molecules for their own replication, remain unknown ...
Leandro Silva da Costa +3 more
doaj +1 more source
Spread of the Sindbis Virus in Fennoscandia
Проблемы особо опасных инфекций, 2023 In the second half of the last century, a persistent focus of the disease caused by Sindbis virus was formed on the territory of Fennoscandia. In different countries, the disease is called Pogosta disease, Ockelbo disease and Karelian fever.
L. V. Rubis
doaj +1 more source
Enzymatic Iodination of Sindbis Virus Proteins [PDF]
Journal of Virology, 1973 Sindbis virus was iodinated by using the enzyme lactoperoxidase, an iodination technique which labels only surface proteins. By this technique, the two viral glycoproteins are labeled, and the internal viral protein is not. The two glycoproteins are iodinated to strikingly different extents. This difference in susceptibility to iodination apparently is
B M, Sefton, G G, Wickus, B W, Burge
openaire +2 more sources
Virology Journal, 2010 We have recently demonstrated an essential role of the domain of 145-150 amino acid in the E2 glycoprotein of Sindbis virus in the interaction with cellular heparan sulfate (HS) and in the infection of mouse embryonic fibroblasts (MEF) cells.
Zhu Wuyang +4 more
doaj +1 more source
First Record of Mosquito-Borne Kyzylagach Virus in Central Europe
Viruses, 2020 RNA of Kyzylagach virus (KYZV), a Sindbis-like mosquito-borne alphavirus from Western equine encephalitis virus complex, was detected in four pools (out of 221 pools examined), encompassing 10,784 female Culex modestus mosquitoes collected at a fishpond ...
Silvie Šikutová +8 more
doaj +1 more source
Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection [PDF]
, 2012 Dynamic, mRNA-containing stress granules (SGs) form in the cytoplasm of cells under environmental stresses, including viral infection. Many viruses appear to employ mechanisms to disrupt the formation of SGs on their mRNAs, suggesting that they represent
Eng, Kai Er +6 more
core +4 more sources
Frontiers in Immunology, 2020 Arboviruses including alphavirus are responsible for most emerging infectious diseases worldwide. Recent outbreaks of chikungunya virus serve as a stark reminder to their pathogenic potential.
Mohanraj Manangeeswaran +4 more
doaj +1 more source
The interferon-stimulated gene IFITM3 restricts infection and pathogenesis of arthritogenic and encephalitic alphaviruses [PDF]
, 2016 Host cells respond to viral infections by producing type I interferon (IFN), which induces the expression of hundreds of interferon-stimulated genes (ISGs).
Diamond, Michael S +4 more
core +2 more sources
Sindbis Virus with a Tricomponent Genome [PDF]
Journal of Virology, 2005 ABSTRACT We established a system for propagation of Sindbis virus (SIN)-based replicons in tissue culture in the form of a tricomponent genome virus. Three RNA fragments containing complementing genetic information required for virus replication are packaged into separate viral particles, and each cell produces at least 1,000 packaged ...
Rafik, Fayzulin +4 more
openaire +2 more sources