Results 81 to 90 of about 1,306 (173)

Orthosiphol A from the Aerial Parts of is Putatively Responsible for Hypoglycemic Effect via α-Glucosidase Inhibition

Natural Product Communications, 2014
An infusion of Orthosiphon aristatus has long been used for diabetes therapy; however, the active principles remained unknown. Herein, we report the identification of the putative agents responsible for this antidiabetic activity using an α-glucosidase ...
Thanakorn Damsud, Mary H. Grace, Sirichai Adisakwattana, Preecha Phuwapraisirisan   +3 more
doaj   +1 more source

In Vitro Lipophilic Antioxidant Capacity, Antidiabetic and Antibacterial Activity of Citrus Fruits Extracts from Aceh, Indonesia

Antioxidants, 2017
This study reports in vitro lipophilic antioxidant, inhibition of α-amylase and antibacterial activities of extracts of peel and pulp of citrus samples from Aceh, Indonesia.
Ernawita, Ruri Agung Wahyuono, Jana Hesse, Uta-Christina Hipler, Peter Elsner, Volker Böhm   +5 more
doaj   +1 more source

Sinensetin Attenuated Macrophagic NLRP3 Inflammasomes Formation via SIRT1-NRF2 Signaling

, 2023
Macrophage-mediated inflammation plays essential roles in multiple-organ injury. Sinensetin (SNS) at least exhibits anti-inflammation, antioxidant, and antitumor properties.
Gen Lu, Zongrong Gong, Gen Lu (8496291), Lin Lin, Huifeng Fan, Zongrong Gong (16946381), Kuimiao Deng, Dongwei Zhang, Lin Lin (46073), Huifeng Fan (10336494), Kuimiao Deng (16946378), Dongwei Zhang (350860)   +11 more
core   +1 more source

DETERMINATION OF IRBESARTAN AND SINENSETIN SIMULTANEOUSLY BY LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY AND THEIR APPLICATION TO DRUG INTERACTION STUDY IN RAT PLASMA [PDF]

, 2016
Objective: To determine and validate of irbesartan and sinensetin simultaneously by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and application of this method to study a pharmacokinetic interaction of irbesartan and ethanol extract of ...
Setiabudy, Rianto, Saputri, Fadlina Chany, Nurmeilis, Harahap, Yahdiana, Munim, Abdul   +4 more
core   +1 more source

Rationale of for Healing Diabetic Foot Ulcer

Natural Product Communications, 2020
Orthosiphon aristatus (Blume) Miq. is traditionally used for wound healing in South East Asia and scientifically proven for its antidiabetic potential.
Farah Izana Abdullah, Lee Suan Chua, Siti Pauliena Mohd Bohari, Eka Sari   +3 more
doaj   +1 more source

Sinensetin suppresses breast cancer cell progression via Wnt/β-catenin pathway inhibition. [PDF]

Transl Cancer Res
Although there are many treatments for breast cancer, such as surgery, radiotherapy, chemotherapy, estrogen receptor antagonists, immune checkpoint inhibitors and so on. However, safer and more effective therapeutic drugs for breast cancer are needed.
Zhu S, Meng L, Wei P, Gu G, Duan K.
europepmc   +3 more sources

QUANTIFICATION OF SINENSETIN IN EXTRACTS OF ORTHOSIPHON STAMINEUS USING HIGH PERFORMANCE THIN-LAYER CHROMATOGRAPHY [PDF]

, 2018
The present study aimed to develop a high performance thin layer chromatography method for the determination of sinensetin and apply it to standardize the extracts Orthosiphon stamineus.
Surriya Naheed, Romea Javed, Amirin Sadikun, Rukhasana Sher, Fakhara Zahid, Naureen Shehzadi, Nadeem Irfan Bukhari, Shaista Qamar, Khalid Hussain*, Zahiri Ismail   +9 more
core  

Simultaneous Quantification and Pharmacokinetic Study of Nine Bioactive Components of Orthosiphon stamineus Benth. Extract in Rat Plasma by UHPLC-MS/MS

Molecules, 2019
Orthosiphon stamineus Benth. (OS) is a traditional folk medicine for the treatment of kidney stones and other urinary tract diseases. In this study, a rapid and sensitive Ultra high-performance liquid chromatography (UHPLC)-MS/MS approach was established
Zili Guo, Bo Li, Jinping Gu, Peixi Zhu, Feng Su, Renren Bai, Xianrui Liang, Yuanyuan Xie   +7 more
doaj   +1 more source

Synthetic pathways of sinensetin and derivatives as an alternate source in biological activity study

Journal of Food Bioactives, 2022
Xiaoqi Wang, Jianfeng Zhan, Chi-Tang Ho, Shiming Li   +3 more
openaire   +1 more source

Natural sources, refined extraction, biosynthesis, metabolism, and bioactivities of dietary polymethoxyflavones (PMFs)

Food Science and Human Wellness
Polymethoxyflavones (PMFs) are a type of uncommon dietary flavonoids, characterized by more than one methoxy group, which exist in limited plant species, like Citrus species and Kaempferia parviflora.
Renyou Gan, Yi Liu, Hang Li, Yu Xia, Huan Guo, Fang Geng, Qiguo Zhuang, Huabin Li, Dingtao Wu   +8 more
doaj   +1 more source