Results 61 to 70 of about 946 (153)

Flavonoids from the Stems of Croton caudatus Geisel. var. tomentosus Hook

Molecules, 2010
A new flavone, named crotoncaudatin (1), was isolated from the stems of Croton caudatus Geisel. var. tomentosus Hook., together with nine known analogues: 3,5,6,7,8,3′,4′-heptamethoxyflavone (2), tangeretin (3), nobiletin (4), 5,6,7,4′-tetramethoxy ...
Zhong-Mei Zou, Jun-Shan Yang, Yuan Wang, Hong-Wu Zhang, Zhi-Heng Su, Guo-An Zou   +5 more
doaj   +1 more source

Recent advancements in citrus by‐product utilization for sustainable food production

Food Biomacromolecules, Volume 2, Issue 3, Page 377-389, September 2025.
Abstract The upcycling of citrus by‐products shows significant potential to combat food waste and create sustainable products for food and nonfood applications. With an annual global production of approximately 124 million tons, citrus fruit processing generates nearly 50% waste, mainly comprising peels, seeds, and membranes. These by‐products are rich
David Evander Jebson Selvaprasad, Keshav Raghav Hegde, Kamatchi Devi Somasundaram, Loganathan Manickam   +3 more
wiley   +1 more source

Flavonoids as Promising Akt1 Inhibitors in Cancer Medicine: Insights From Molecular Docking, Dynamics, DFT Calculations, and In Vitro Validation

Cancer Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background The PI3K/Akt/mTOR signaling pathway is commonly deregulated in different types of cancers, contributing to tumor proliferation, persistence, and resistance to treatment. Akt1, a crucial kinase within this pathway, plays a critical role in tumor progression and the occurrence of therapeutic resistance.
Shokoofeh Jamshidi, Ali Eghbalian, Setareh Shojaei, Amir Taherkhani, Mehran Feizi‐Dehnayebi   +4 more
wiley   +1 more source

Alleviating Effects of Citrus Polymethoxyflavones on Autoimmune Thyroiditis via IL‐17 Signaling Pathway

Food Frontiers, Volume 6, Issue 4, Page 1887-1902, July 2025.
Citrus flavonoid extracts reduced TPO‐ Ab levels in AITDs cell models. PMFs exhibited the strongest effect on alleviating AITDs among citrus flavonoids. Tangeretin modulated IL‐ 17 signaling pathway to prevent AITDs, and reduced NaI‐ induced thyroid damage in AITDs mouse model.
Manxi Wu, Han Yang, Yuhao Wu, Yuanxiao Yin, Junhao Li, Yongfu Ge, Cui Sun, Jinping Cao, Dengliang Wang, Yixiong Zheng, Yue Wang, Chongde Sun   +11 more
wiley   +1 more source

The Multifaceted Roles of BACH1 in Disease: Implications for Biological Functions and Therapeutic Applications

Advanced Science, Volume 12, Issue 10, March 13, 2025.
BACH1, a basic leucine zipper protein ubiquitously expressed in mammalian tissues, plays a critical role in the regulation of oxidative stress, cell cycle progression, heme homeostasis, and immune responses. It is implicated in cardiovascular diseases, cancer progression, neurodegenerative disorders, and many other diseases.
Xiangxiang Wei, Yunquan He, Yueyang Yu, Sichong Tang, Ruiwen Liu, Jieyu Guo, Qingjun Jiang, Xiuling Zhi, Xinhong Wang, Dan Meng   +9 more
wiley   +1 more source

Sinensetin suppresses breast cancer cell progression via Wnt/β-catenin pathway inhibition. [PDF]

Transl Cancer Res
Although there are many treatments for breast cancer, such as surgery, radiotherapy, chemotherapy, estrogen receptor antagonists, immune checkpoint inhibitors and so on. However, safer and more effective therapeutic drugs for breast cancer are needed.
Zhu S, Meng L, Wei P, Gu G, Duan K.
europepmc   +3 more sources

Structural insights and biological activities of flavonoids: Implications for novel applications

Food Frontiers, Volume 6, Issue 1, Page 218-247, January 2025.
It provides a theoretical basis for the development of new applications of flavonoids and facilitates the targeted functional molecular design and development in the food and pharmaceutical industries. In this paper, the structural characteristics of flavonoids were summarized, and the biosynthesis, digestion and absorption of flavonoids in vivo were ...
Sheng Tang, Botao Wang, Xin Liu, Wenxia Xi, Yuanyuan Yue, Xiang Tan, Junying Bai, Linhua Huang   +7 more
wiley   +1 more source

Unveiling the potentials and action mechanisms of Citri reticulatae Pericarpium as an anti‐inflammatory food

Food Frontiers, Volume 6, Issue 1, Page 163-184, January 2025.
The review summarized advances in utilizing CRP for the prevention and treatment of inflammation under various pathological conditions. The underlying mechanism has focused on polymethoxyflavones (PMFs) present in CRP and its interaction with gut microbiota. Abstract Modern lifestyle has led human body under a frequent exposure of chronic inflammation.
Yanyi Li, Ying Chen, Yue Zhou, Jiayi He, Qian Zhou, Mingfu Wang   +5 more
wiley   +1 more source

Comprehensive metabolome characterization of leaves, internodes, and aerial roots of Vanilla planifolia by untargeted LC–MS and GC × GC–MS

Phytochemical Analysis, Volume 36, Issue 1, Page 30-51, January 2025.
Abstract Introduction Untargeted metabolomics is a powerful tool that provides strategies for gaining a systematic understanding of quantitative changes in the levels of metabolites, especially when combining different metabolomic platforms. Vanilla is one of the world's most popular flavors originating from cured pods of the orchid Vanilla planifolia.
Falco Beer, Christoph H. Weinert, Johannes Wellmann, Silke Hillebrand, Jakob Peter Ley, Sebastian T. Soukup, Sabine E. Kulling   +6 more
wiley   +1 more source

Agronomy Character and Sinensetin Content of Several Java’s Tea Plant Accession (Orthosiphon stamineus)

Jurnal Hortikultura Indonesia, 2019
Tanaman kumis kucing berkhasiat untuk mengobati penyakit diabetes. Sinensetin merupakan senyawa kimia pada kumis kucing yang berperan sebagai obat diabetes. Tujuan penelitian adalah untuk mempelajari keragaman karakter agronomi dan kandungan sinensetin tanaman kumis kucing hasil koleksi ex situ dari daerah Jawa Barat, Jawa Tengah dan Jawa Timur ...
Shalati Febjislami, Maya Melati, Ani Kurniawati, Yudiwanti Wahyu   +3 more
openaire   +2 more sources