Results 41 to 50 of about 1,306 (173)

Sinensetin suppresses angiogenesis in liver cancer by targeting the VEGF/VEGFR2/AKT signaling pathway

Experimental and Therapeutic Medicine, 2022
Sinensetin (SIN) is a polymethoxy flavone primarily present in citrus fruits. This compound has demonstrated anticancer activity. However, the underlying mechanism of its action has not been fully understood. The present study investigated the impact of SIN on angiogenesis in a liver cancer model.
Li, Xiao, Li, Yan, Wang, Yuan, Liu, Fuhong, Liu, Yanjun, Liang, Jiangjiu, Zhan, Rucai, Wu, Yue, Ren, He, Zhang, Xiuyuan, Liu, Ju   +10 more
openaire   +2 more sources

Seasonal Effect of Ultraviolet Irradiation on Polymethoxyflavone and Hesperidin Content in Ponkan and Tachibana Flavedo

HortScience, 2020
Ponkan (Citrus reticulate) and Tachibana (Citrus tachibana) contain large amounts of polymethoxyflavones (PMFs). To produce highly functional food with high potential, it is important to develop technologies to increase their PMF content.
Ittetsu Yamaga , Sakura Hamasaki
doaj   +1 more source

Phytochemical Analysis and Biological Activities of the Ethanolic Extract of Daphne sericea Vahl Flowering Aerial Parts Collected in Central Italy

Biomolecules, 2021
In this paper, the first phytochemical analysis of the ethanolic extract of Daphne sericea Vahl flowering aerial parts collected in Italy and its biological activities were reported.
Claudio Frezza, Alessandro Venditti, Daniela De Vita, Fabio Sciubba, Pierpaolo Tomai, Marco Franceschin, Mirella Di Cecco, Giampiero Ciaschetti, Antonella Di Sotto, Annarita Stringaro, Marisa Colone, Alessandra Gentili, Mauro Serafini, Armandodoriano Bianco   +13 more
doaj   +1 more source

Comparison of Polyphenol Levels of Callus and Wild Type of Cat's Whiskers Plant ( Orthosiphon aristatus (Blume) Miq.) Purple Varieties

Journal of Applied Agricultural Science and Technology, 2022
The cat's whiskers plant ( Orthosiphon aristatus (Blume) Miq) that grows in Indonesia has white flowers, purple flowers, and white flowers with purple patterns.
Fahrauk Faramayuda, Soraya Riyanti, Ari Sri Widyaswari, Zaini Alfahmi, Sultan Salahudin Jamal, Totik Sri Mariani, Elfahmi Elfahmi, Sukrasno Sukrasno   +7 more
doaj   +1 more source

Supercritical carbon dioxide extraction of sinensetin, isosinensetin, and rosmarinic acid from orthosiphon stamineus leaves: optimization and modeling

, 2020
Due to the health benefits such as anti-diabetic, antioxidant, and anti-inflammatory agents, the extraction of bioactive compounds from natural plants becomes significant.
Abdul Aziz, Ahmad Hazim, Putra, Nicky Rahmana, Che Yunus, Mohd. Azizi, Kong, Helen   +3 more
core   +1 more source

<i>Exocarpium Citri Grandis</i> Ameliorates Metabolic Disorders by Inhibiting Inflammatory Responses and NLRP3 Inflammasome Activation. [PDF]

Food Sci Nutr
Exocarpium Citri Grandis (ECG, Huajuhong in Chinese), as the fruit of a plant that can be used both as medicine and food, has gained attention for hypolipidemic and anti‐obesity effects. To our knowledge, this is an innovative study based on in vivo and in vitro experiments aimed at exploring the pharmacological mechanisms of ECG in ameliorating MS ...
Chen T, Wu X, Wang D, Cui T, Li J, Zhang Z, Qiu M, Ma C, Liu H, Gao Y, Zeng J, Li H, Huang J.   +12 more
europepmc   +2 more sources

Transcriptome analysis of sinensetin-treated liver cancer cells guided by biological network analysis

Oncology Letters, 2021
Hepatocellular carcinoma is recognized as one of the most frequently occurring malignant types of liver cancer globally, making the identification of biomarkers critically important. The aim of the present study was to identify the genes involved in the anticancer effects of flavonoid compounds so that they may be used as targets for cancer treatment ...
Kim, Seong Min, Rampogu, Shailima, Vetrivel, Preethi, Kulkarni, Apoorva M., Ha, Sang Eun, Kim, Hun Hwan, Lee, Keun Woo, Kim, Gon Sup   +7 more
openaire   +3 more sources

Syntheses of 6-Hydroxyluteolin and Sinensetin by Wessely — Moser Rearrangement

, 1988
Chemistry Department, Patna University, Patna-800 005 Manuscript received 19 June 1987, accepted 30 December 1987 Syntheses of 6-hydroxyluteolin (1) and sinensetin (2) are described. The com­pounds 6 and 7 afford 1 on Wessely — Moser rearrangement. The synthetic samples 1 and 2 are identical (m.m.p. and co-ir) with the authentic samples.
S. C. SHAW, (Mrs.) R. AZAD, S. P. MANDAL, R. S. GANDHI   +3 more
openaire   +2 more sources

HPLC and Anti-Inflammatory Studies of the Flavonoid Rich Chloroform Extract Fraction of Orthosiphon Stamineus Leaves

Molecules, 2010
The aim of the present study was to verify the anti-inflammatory activity of Orthosiphon stamineus leaf extracts and to identify the active compound(s) contributing to its anti-inflammatory activity using a developed HPLC method.
Mun Fei Yam, Vuanghao Lim, Ibrahim Muhammad Salman, Omar Ziad Ameer, Lee Fung Ang, Noersal Rosidah, Muthanna Fawzy Abdulkarim, Ghassan Zuhair Abdullah, Rusliza Basir, Amirin Sadikun, Mohd Zaini Asmawi   +10 more
doaj   +1 more source

“Drying effect” of fructus aurantii components and the mechanism of action based on network pharmacology and in vitro pharmacodynamic validation

Frontiers in Pharmacology, 2023
Background: Fructus aurantii (FA) is the dried, unripe fruit of the plant Citrus aurantium L. and its cultivated varieties. We investigated the drying effect of FA components and how this drying affect is achieved.Methods: We employed systems ...
Jing Zhu, Yi Luo, Hengli Tong, Lingyun Zhong, Qianfeng Gong, Yaqi Wang, Ming Yang, Qing Song   +7 more
doaj   +1 more source