Results 41 to 50 of about 946 (153)

Unraveling the Bioactive Compounds and Multi‐Target Mechanisms of the Fructus Aurantii Immaturus‐Bambusae Caulis in Taeniam Herb Pair Against Chronic Gastritis: Integrating Identification of Absorbed Constituents, Targeted Network Pharmacology, and Computational Validation

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This work systematically explored the anti‐chronic gastritis mechanism of the FAI‐BCT herb pair. UPLC‐Q‐TOF‐MS/MS was applied to identify absorbed prototypes and metabolites of FAI‐BCT in rat plasma. Combining database mining, network pharmacology, molecular docking, and molecular dynamics simulation, we screened the key bioactive components and core ...
Yinghua Ma, Weiwei Xie, Jing Song, Yabin Qin, Yile Zhao   +4 more
wiley   +1 more source

Protective effects of sinensetin on intestinal barrier damage induced by lipopolysaccharide in mice through TLR4/NLRP3/GSDMD pathway

Journal of Agriculture and Food Research
Recent studies have increasingly indicated that sinensetin, a dietary-derived natural compound and key component of orange peel, can alleviate intestinal damage induced by cisplatin.
Zhuoqun Meng, Qin Zhang, Ranran Zhang, Guirong Liu, Wenliang Xiang, Yang He, Qing Zhang, Jie Tang   +7 more
doaj   +1 more source

Comparative effects of five polymethoxyflavones purified from Citrus tangerina on inflammation and cancer

Frontiers in Nutrition, 2022
Although the Citrus tangerina cultivar “Dahongpao” (CTD) has been established as a rich source of polymethoxyflavones (PMFs) with anti-inflammatory and anti-cancer properties, their individual effects on cellular signaling remain to be elucidated.
Qiyang Chen, Yue Gu, Chun Tan, Balasubramani Sundararajan, Zhenqing Li, Dan Wang, Zhiqin Zhou, Zhiqin Zhou   +7 more
doaj   +1 more source

Endophyte‐induced systemic spatial reprogramming of metabolism in Populus trichocarpa roots under drought

New Phytologist, Volume 251, Issue 1, Page 438-454, July 2026.
Summary Beneficial, facultative endophytes help plants thrive in challenging environments by altering their host's metabolism, but how these cellular scale metabolic changes propagate to the systems biology scale is unknown. In this work, we employed a high‐resolution chemical imaging approach to map metabolic changes at the Populus trichocarpa root ...
Jayde Aufrecht, Dušan Veličković, Robert Tournay, Sneha Couvillion, Vimal Balasubramanian, Tanya Winkler, Daisy Herrera, Robert Stanley, Sharon L. Doty, Amir H. Ahkami   +9 more
wiley   +1 more source

Profiling Rosmarinic Acid and Sinensetin Content of Orthosiphon aristatus. from Three Different Locations with Variety Ethanol Concentration

Journal of Food and Pharmaceutical Sciences
Orthosiphon aristatus is a well-known medicinal plant acknowledged for its therapeutic effect in treating urinary tract diseases, hypertension, diabetes mellitus, and arthritis.
Novia Putri Ramadhani, Yosi Bayu Murti, Andayana Puspitasari Gani   +2 more
doaj   +1 more source

Orthosiphon stamineus Benth. is an outstanding food medicine: Review of phytochemical and pharmacological activities

Journal of Pharmacy and Bioallied Sciences, 2018
Orthosiphon stamineus Benth. (Lamiaceae) is a valued medicinal plant in traditional folk medicine. Many pharmacological studies have demonstrated the ability of this plant to exhibit antimicrobial, antioxidant, hepatoprotection, antigenotoxic ...
Kamran Ashraf, Sadia Sultan, Aishah Adam
doaj   +1 more source

Antibiofilm Efficacies of Flavonoid-Rich Sweet Orange Waste Extract against Dual-Species Biofilms

Pathogens, 2023
The current study evaluated the antibacterial properties of industrial sweet orange waste extracts (ISOWEs), which are a rich source of flavonoids. The ISOWEs exhibited antibacterial activity towards the dental cariogenic pathogens Streptococcus mutans ...
Suvro Saha, Thuy Do, Joanne Maycock, Simon Wood, Christine Boesch   +4 more
doaj   +1 more source

Citrus reticulata Blanco: A Review on Chemical Composition and Biological Activities

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
This review compiles chemical information and biological activities from 49 studies on Citrus reticulata. The fruit peels stand out for their high content of methoxylated monoterpenes and flavonoids with antioxidant, anti‐inflammatory, and antimicrobial activities.
José Walber Gonçalves Castro, Geane Gabriele de Oliveira Souza, José Galberto Martins da Costa, Fabíola Fernandes Galvão Rodrigues   +3 more
wiley   +1 more source

Sinensetin-Rich Fraction Solid Dispersion Inhibits Cancer Cell Cycle

KnE Life Sciences, 2017
Drug development efforts to find new selective and safe drugs for cancer from natural resources are promising ones. The natural products are obtained in the multiple or single compounds. One of them is a sinensetin found in ethanol extract of Orthosiphon stamineus Benth. Sinensetin could inhibit cancer cell proliferation.
Lusiana Arifianti, Sukardiman Sukardiman, Mulja Hadi Santosa   +2 more
openaire   +2 more sources

Dual‐Pathway Defense: Ultramicro‐Pulverised Powder of Polygonum chinense L. and Atractylodes rhizome (PAUP) Rescues Broilers From E. coli‐Triggered Liver Injury Through Modulation of Oxidative Stress and Inflammation

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Reduced Antibiotic residues and resistance concerns: Offers a potential natural alternative to antibiotics for combating E. coli infections in poultry. Provided safer poultry food products: By enhancing liver function, restoring weight gain, and improving feed efficiency, PAUP supports the production of healthier chickens, ultimately contributing to ...
Jia‐Ci Cai, Yan‐Na Guo, Shao‐Shan Liang, Yan Liu, Fu‐Qiang Huang, Qi‐Peng Lv, Lan‐Yi Zhang, Yi Qin, Xiao‐Jing Chen, Yu‐Xin Liang, Yong‐Ming He, Lu‐Ping Tang   +11 more
wiley   +1 more source