Results 51 to 60 of about 1,306 (173)

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source

Sinensetin induces apoptosis and autophagy in the treatment of human T-cell lymphoma

, 2023
The present study was carried out to explore the effect of sinensetin in human T-cell lymphoma Jurkat cells and to reveal the underlying molecular mechanisms.
Yu-Tang Tung, Chi-Chien Lin, Shih-Chao Lin, Meng-Xian Lin, Sheng-Hao Lin, Kok-Tong Tan   +5 more
core  

Protective effects of sinensetin on intestinal barrier damage induced by lipopolysaccharide in mice through TLR4/NLRP3/GSDMD pathway

Journal of Agriculture and Food Research
Recent studies have increasingly indicated that sinensetin, a dietary-derived natural compound and key component of orange peel, can alleviate intestinal damage induced by cisplatin.
Zhuoqun Meng, Qin Zhang, Ranran Zhang, Guirong Liu, Wenliang Xiang, Yang He, Qing Zhang, Jie Tang   +7 more
doaj   +1 more source

Comparative effects of five polymethoxyflavones purified from Citrus tangerina on inflammation and cancer

Frontiers in Nutrition, 2022
Although the Citrus tangerina cultivar “Dahongpao” (CTD) has been established as a rich source of polymethoxyflavones (PMFs) with anti-inflammatory and anti-cancer properties, their individual effects on cellular signaling remain to be elucidated.
Qiyang Chen, Yue Gu, Chun Tan, Balasubramani Sundararajan, Zhenqing Li, Dan Wang, Zhiqin Zhou, Zhiqin Zhou   +7 more
doaj   +1 more source

Metabolomics and Mechanistic Approaches Reveal the Synergistic and Attenuating of Rubus chingii Hu on Tripterygium Glycoside Tablets in the Treatment of Rheumatoid Arthritis

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Experimental flow chart of the attenuating and synergistic effects of RCH on TGTs in the treatment of rheumatoid arthritis. ABSTRACT Tripterygium Glycoside Tablets (TGTs) are primary drugs for rheumatoid arthritis (RA) but pose a risk of nephrotoxicity. Rubus chingii Hu (RCH) may enhance kidney function.
Cong Zhang, Zepeng Zhang, Fang Yan, Lei Zhang   +3 more
wiley   +1 more source

Orthosiphon stamineus Benth. is an outstanding food medicine: Review of phytochemical and pharmacological activities

Journal of Pharmacy and Bioallied Sciences, 2018
Orthosiphon stamineus Benth. (Lamiaceae) is a valued medicinal plant in traditional folk medicine. Many pharmacological studies have demonstrated the ability of this plant to exhibit antimicrobial, antioxidant, hepatoprotection, antigenotoxic ...
Kamran Ashraf, Sadia Sultan, Aishah Adam
doaj   +1 more source

Development of an HPLC Method for Simultaneous Quantification of Rosmarinic Acid, Sinensetin in Herba Orthosiphonis spiralis

VNU Journal of Science: Medical and Pharmaceutical Sciences, 2023
The purpose of this study was to develop an HPLC method for the simultaneous quantification of rosmarinic acid and sinensetin in Herba Orthosiphonis spiralis. The chromatographic separation was performed on an Ascentis®C8 column (250 × 4.6 mm, 5 µm) using a gradient elution mode with acetonitrile and water containing 0.1% formic acid as mobile phase ...
Hoang Thi Thao, Nguyen Thi Bich Huong, Ngo Thi Xuan Thinh, Dao Viet Hung, Nguyen Xuan Truong, Nguyen Thanh Hai, Ha Thanh Hoa, Tran Thi Van Anh, Nguyen Thi Minh Diep, Pham Quoc Tuan   +9 more
openaire   +1 more source

Antibiofilm Efficacies of Flavonoid-Rich Sweet Orange Waste Extract against Dual-Species Biofilms

Pathogens, 2023
The current study evaluated the antibacterial properties of industrial sweet orange waste extracts (ISOWEs), which are a rich source of flavonoids. The ISOWEs exhibited antibacterial activity towards the dental cariogenic pathogens Streptococcus mutans ...
Suvro Saha, Thuy Do, Joanne Maycock, Simon Wood, Christine Boesch   +4 more
doaj   +1 more source

Effect of thermosonication on the UHPLC‐QTOF‐IMS‐based metabolomic profile of orange juice

JSFA reports, Volume 6, Issue 8, Page 309-313, August 2026.
Abstract Background This study investigated the impact of thermosonication on the metabolomic profile of orange juice to understand processing‐induced alterations in bioactive compounds and quality attributes. Results Moderate thermosonication at 45°C preserved structural siloxanes and certain amino acids, whereas higher temperatures between 60 and 75 ...
Deepti Kothari, Arun Kumar, Saloni Joshi, Desta Dugassa Fufa, Sajad Ali   +4 more
wiley   +1 more source

Unraveling the Bioactive Compounds and Multi‐Target Mechanisms of the Fructus Aurantii Immaturus‐Bambusae Caulis in Taeniam Herb Pair Against Chronic Gastritis: Integrating Identification of Absorbed Constituents, Targeted Network Pharmacology, and Computational Validation

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This work systematically explored the anti‐chronic gastritis mechanism of the FAI‐BCT herb pair. UPLC‐Q‐TOF‐MS/MS was applied to identify absorbed prototypes and metabolites of FAI‐BCT in rat plasma. Combining database mining, network pharmacology, molecular docking, and molecular dynamics simulation, we screened the key bioactive components and core ...
Yinghua Ma, Weiwei Xie, Jing Song, Yabin Qin, Yile Zhao   +4 more
wiley   +1 more source