Results 51 to 60 of about 946 (153)

Sinensetin ameliorates established high-fat diet-induced liver injury and intestinal barrier dysfunction through the mitophagy/TLR4/MAPK signaling pathway

Frontiers in Nutrition
IntroductionLong-term consumption of a high-fat diet (HFD) causes liver injury characterized by steatosis, inflammation, and fibrosis. Mitophagy, as a selective autophagy, is reported to be involved in the regulation of liver injury.
Zhuoqun Meng, Qin Zhang, Zhichang Zhao, Yuan Zhang, Zhijie Lu, Guirong Liu, Wenliang Xiang, Qing Zhang, Jie Tang, Jie Tang   +9 more
doaj   +1 more source

Characterization and Mechanism Prediction of Active Components in Fuganlin Oral Liquid for Respiratory Tract Infections Using UPLC–Q‐TOF–MS and Network Pharmacology

Journal of Analytical Methods in Chemistry, Volume 2026, Issue 1, 2026.
Fuganlin oral liquid (FOL) has been clinically employed for the treatment of pediatric qi deficiency colds, manifesting symptoms such as fever, cough, asthma, and sore throat. However, the chemical composition and bioactive components of FOL have not been clearly elucidated.
Mengyue Zhang, Feng Han, Mingxuan Yang, Zhishan Ye, Ying Cui, Yuefei Wang, Jing Yang, Xin Chai, Rongda Xu   +8 more
wiley   +1 more source

A NEW PRENYLATED FLAVANONE FROM THE ARIAL PART OF Orthosiphon stamineus

Indonesian Journal of Chemistry, 2010
Phytochemical investigations on the chloroform extract of the arial part of Orthosiphon stamineus resulted in isolation of one new prenylated compound 5,7-dimethoxy-3,4′-dihydroxy-3′,8-di-C-prenylflavanone together with four known flavonoids compounds ...
M. Amzad Hossain, Atiqur Rahman, Sun Chul Kang   +2 more
doaj   +1 more source

Development of an HPLC Method for Simultaneous Quantification of Rosmarinic Acid, Sinensetin in Herba Orthosiphonis spiralis

VNU Journal of Science: Medical and Pharmaceutical Sciences, 2023
The purpose of this study was to develop an HPLC method for the simultaneous quantification of rosmarinic acid and sinensetin in Herba Orthosiphonis spiralis. The chromatographic separation was performed on an Ascentis®C8 column (250 × 4.6 mm, 5 µm) using a gradient elution mode with acetonitrile and water containing 0.1% formic acid as mobile phase ...
Hoang Thi Thao, Nguyen Thi Bich Huong, Ngo Thi Xuan Thinh, Dao Viet Hung, Nguyen Xuan Truong, Nguyen Thanh Hai, Ha Thanh Hoa, Tran Thi Van Anh, Nguyen Thi Minh Diep, Pham Quoc Tuan   +9 more
openaire   +1 more source

Analysis of the Functional Components of Four “Sanghuang”‐Like Species Using UPLC‐ESI‐MS/MS‐Based Widely Targeted Metabolomics and TCMSP Database

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
“Sanghuang” is a rare, edible, medicinal macrofungus. However, various macrofungi that share similar appearances, habitats, and therapeutic effects with “Sanghuang” have been erroneously used in traditional folk medicine. As of date, metabolic differences among these “Sanghuang”‐like species have been unclear, impeding their commercial utilization ...
Xiao-Ying Guo, Yue Qi, Xiao-Dan Yu, Ai-Guo Xu, Chun-Yang Zhi, Hong-Bo Guo, Charalampos Proestos   +6 more
wiley   +1 more source

Solvation Free Energy Simulation for Rosmarinic Acid Extraction from Orthosiphon stamineus

Methods and Protocols, 2019
This study was aimed to extract rosmarinic acid from Orthosiphon stamineus Benth. (Lamiaceae) in high yield. The mixture of chloroform−ethyl acetate (70:30) was chosen as the solvent system because rosmarinic acid gave the lowest solvation free ...
Cher Haan Lau, Lee Suan Chua
doaj   +1 more source

Natural Pesticides in Crop Protection: Comparative Advantages, Ecological Risks, and Future Directions

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Although synthetic pesticides have long been used to protect crops, their widespread use has led to significant health and environmental problems, including ecological contamination, resistant pest populations, and hazardous residues in food. These restrictions have sparked interest in natural pesticides (NPs), particularly the secondary metabolites of
Ruth Mwangi, Njogu M. Kimani, Munmun Bardhan   +2 more
wiley   +1 more source

Cytotoxic Effects of Some Flavonoids and Imatinib on the K562 Chronic Myeloid Leukemia Cell Line: Data Analysis Using the Combination Index Method

Balkan Medical Journal, 2019
Background:Flavonoids are natural compounds with antioxidant, anticarcinogenic, and anti-inflammatory effects.Aims:To determine the cytotoxic effects of flavonoids and drug resistance related to P-gp on K562 human chronic myeloid leukemia cells.
Ferdane Danışman Kalındemirtaş, Hüsniye Birman, Eda Candöken, Sema Bilgiç Gazioğlu, Gülay Melikoğlu, Serap Kuruca   +5 more
doaj   +1 more source

Sonochemical effects on 14 flavonoids common in citrus: relation to stability. [PDF]

PLoS ONE, 2014
The sonochemical effects of ultrasound (US) treatment on 14 flavonoids representing the main flavonoids in citrus fruit were investigated in a standard mixture by stability evaluation of a model system.
Liping Qiao, Yujing Sun, Rongrong Chen, Yu Fu, Wenjuan Zhang, Xin Li, Jianchu Chen, Yan Shen, Xingqian Ye   +8 more
doaj   +1 more source

Natural variation of the wheat root exudate metabolome and its influence on biological nitrification inhibition activity

Plant Biotechnology Journal, Volume 23, Issue 11, Page 4755-4772, November 2025.
Summary Excessive nitrogen use and low nitrogen use efficiency (NUE) in current agroecosystems are disrupting the global nitrogen cycle. Chemical inhibitors offer only temporary relief, while plant‐derived biological nitrification inhibitors (BNIs) remain safer but underexplored.
Arindam Ghatak, Alexandros E. Kanellopoulos, Cristina López‐Hidalgo, Andrea Malits, Yuhang Meng, Florian Schindler, Shuang Zhang, Jiahang Li, Steffen Waldherr, Hugo Ribeiro, Melina Kerou, Logan H. Hodgskiss, Maximilian Dreer, Reyazul Rouf Mir, Sandeep Sharma, Gert Bachmann, Dimitrios G. Karpouzas, Christa Schleper, Evangelia S. Papadopoulou, Palak Chaturvedi, Wolfram Weckwerth   +20 more
wiley   +1 more source