Results 31 to 40 of about 1,306 (173)

Sinensetin Attenuated Macrophagic NLRP3 Inflammasomes Formation via SIRT1-NRF2 Signaling

ACS Omega, 2023
Macrophage-mediated inflammation plays essential roles in multiple-organ injury. Sinensetin (SNS) at least exhibits anti-inflammation, antioxidant, and antitumor properties. However, the underlying mechanism of SNS-targeted macrophage-mediated inflammation remains elusive. In the present study, our results showed that SNS suppressed lipopolysaccharide (
Lin Lin, Kuimiao Deng, Zongrong Gong, Huifeng Fan, Dongwei Zhang, Gen Lu   +5 more
doaj   +3 more sources

Identification of Citri Reticulatae Pericarpium (Chenpi) From Different Cultivars via LC-MS/MS and UPLC Coupled With Multivariate Chemometrics Analysis. [PDF]

Food Sci Nutr
A UPLC‐based quantitative analysis combined with multivariate chemometric methods differentiated seven Citri Reticulatae Pericarpium cultivars based on significant variations in nine flavonoids. Chemometric analysis effectively separated the seven cultivars, and hesperetin was identified as a unique marker for C. reticulata “Chachi”.
Lin D, Zhang J, Chen M, Zhong C, Cao H, Ma Z, Wu M, Zhang Y.   +7 more
europepmc   +2 more sources

α-Glucosidase Inhibitory Potential of <i>Citrus reticulata</i> Peel-Derived Flavonoids-A Prelude for the Management of Type 2 Diabetes. [PDF]

Food Sci Nutr
Flavonoids derived from Citrus reticulate peel inhibit α‐glucosidase activity, delaying carbohydrate digestion and reducing glucose absorption, thereby indicating their potential as functional food components for type 2 diabetes management. ABSTRACT α‐Glucosidase inhibitors (AGIs) are compounds used to treat type 2 diabetes (T2D) by preventing the ...
Baloyi IT, Rabbad AH, Gama NH, Malgas S.
europepmc   +2 more sources

Bacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage. [PDF]

Adv Sci (Weinh)
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Su J, Zhang S, Liang L, Bai H, Bai M, He H, Wang Y, Liu H, Liang X, Sun Y, Wu H.   +10 more
europepmc   +2 more sources

Pengaruh Stres Kekeringan terhadap Pertumbuhan dan Kandungan Sinensetin Tanaman Kumis Kucing (Orthosiphon aristatus (Blume) Miq.) [PDF]

, 2023
The response of plants to environmental stress depends on the type of plant, the level, and the duration of stress. Drought stress affects growth, development, and the content of secondary metabolites produced by the plant.
Hadiyanti, Nugraheni; Kadiri University, Muharram, Muhammad, Probojati, Rasyadan Taufiq   +2 more
core   +2 more sources

Effect of Media Variation on the Induction and Phytochemical Profile of Callus in Two Varieties of Cat's Whiskers (Orthosiphon aristatus Blume Miq)

Hayati Journal of Biosciences, 2022
The levels of rosmarinic acid and sinensetin in purple and white-purple varieties of Orthosiphon aristatus, cat's whiskers, can be increased using modified in vitro culture. This work focused on callus induction of the purple and white-purple variety of
Fahrauk Faramayuda, Akhirul Kahfi Syam, Totik Sri Mariani, Elfahmi, Sukrasno   +4 more
doaj   +1 more source

Sinensetin Reduces Osteoarthritis Pathology in the Tert-Butyl Hydroperoxide-Treated Chondrocytes and the Destabilization of the Medial Meniscus Model Mice via the AMPK/mTOR Signaling Pathway

Frontiers in Pharmacology, 2021
As a common degenerative disease, osteoarthritis (OA) usually causes disability in the elderly and socioeconomic burden. Previous studies have shown that proper autophagy has a protective effect on OA.
Wenxian Zhou, Wenxian Zhou, Wenxian Zhou, Yifeng Shi, Yifeng Shi, Yifeng Shi, Hui Wang, Hui Wang, Hui Wang, Caiyu Yu, Huanqing Zhu, Aimin Wu, Aimin Wu, Aimin Wu   +13 more
doaj   +1 more source

EXTRACTION AND MICROENCAPSULATION OF POLYPHENOLS FROM ORTHOSIPHON STAMINEUS LEAVES [PDF]

Journal of Mechanical Engineering and Sciences, 2014
This paper presents an extraction and microencapsulation study of polyphenols obtained from Orthosiphon stamineus leaves. Extraction using aqueous solvent enabled a simultaneous extraction of both hydrophilic and lipophilic phenolic compounds.
S. F. Pang, M. M. Yusoff, J. Gimbun
doaj   +1 more source

Enhancement and optimization of sinensetin extract from orthosiphon stamineus using supercrtitical carbon dioxide extraction [PDF]

, 2018
Sinensetin is a rare valuable flavonoid compound that contains 5 methoxy groups attached on the flavone backbone. This compound is abundantly established in citrus peel and can also be found in medicinal herb, ‘misai kucing’.
Abdul Aziz, Ahmad Hazim, Mohd. Hadzri, Hafizah, Che Yunus, Mohd. Azizi, Lee, Nian Yian, Mustapha, Ana Najwa, Idham, Zuhaili, Rithwan, Fahim   +6 more
core   +1 more source

Storage-Induced Changes in Phenolic Profile and Antioxidant Capacity of Functional Blueberry Beverages Enriched With Propolis. [PDF]

Food Sci Nutr
Development of functional blueberry beverages enriched with propolis extracts prepared using different solvent systems (water, glycerol–water, and propylene glycol–water). Propolis enrichment and storage conditions influenced the phenolic profile, antioxidant capacity, and physicochemical properties of the beverages during 12 months of storage in glass
Sengul M, Zor M, Ufuk S, Karakutuk İA, Aksoy S, Topdas EF.   +5 more
europepmc   +2 more sources