Journal of Applied Pharmaceutical Science, 2022 Orthosiphon stamineus is widely used as an ingredient in traditional medicine and functional food partially for its main active compound, sinensetin. Plant growth and sinensetin contents are sensitive to many variables, including phytogeographical profiles. This study sought to evaluate the quality of O.
Kartini, Kartini +2 more
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Sinensetin suppresses breast cancer cell progression via Wnt/β-catenin pathway inhibition. [PDF]
Transl Cancer ResAlthough there are many treatments for breast cancer, such as surgery, radiotherapy, chemotherapy, estrogen receptor antagonists, immune checkpoint inhibitors and so on. However, safer and more effective therapeutic drugs for breast cancer are needed.
Zhu S, Meng L, Wei P, Gu G, Duan K.
europepmc +3 more sources
Evaluation of α-Glucosidase Inhibitory Effect of 50% Ethanolic Standardized Extract of Orthosiphon stamineus Benth in Normal and Streptozotocin-Induced Diabetic Rats [PDF]
, 2015 In the present study, a 50% ethanolic extract of Orthosiphon stamineus was tested for its α-glucosidase inhibitory activity. In vivo assays of the extract (containing 1.02%, 3.76%, and 3.03% of 3′hydroxy-5,6,7,4′-tetramethoxyflavone, sinensetin, and ...
Ahmad, Mariam +4 more
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Oncology Letters, 2021 Hepatocellular carcinoma is recognized as one of the most frequently occurring malignant types of liver cancer globally, making the identification of biomarkers critically important. The aim of the present study was to identify the genes involved in the anticancer effects of flavonoid compounds so that they may be used as targets for cancer treatment ...
Kim, Seong Min +7 more
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Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2021 Background: Diabetes Mellitus (DM) is a complex chronic disease characterized by increased blood glucose. The incidence of this disease is rising, especially type 2 diabetes which is caused by insulin resistance in the body.
Intan Kris Prasetyanti +2 more
doaj +1 more source
Antioxidant and Toxicity Studies of 50% Methanolic Extract of Orthosiphon stamineus Benth [PDF]
, 2013 The present study evaluated the antioxidant activity and potential toxicity of 50% methanolic extract of Orthosiphon stamineus (Lamiaceae) leaves (MEOS) after acute and subchronic administration in rats.
Ahmad, Mariam +7 more
core +1 more source
Preparation and characterization of nano liposomes of Orthosiphon stamineus ethanolic extract in soybean phospholipids [PDF]
, 2014 BACKGROUND: O. stamineus is a medicinal herb with remarkable pharmacological properties. However, poor solubility of the active principles limits its medicinal value.
Abdalrahim FA Aisha +2 more
core +1 more source
EXTRACTION AND MICROENCAPSULATION OF POLYPHENOLS FROM ORTHOSIPHON STAMINEUS LEAVES [PDF]
Journal of Mechanical Engineering and Sciences, 2014 This paper presents an extraction and microencapsulation study of polyphenols obtained from Orthosiphon stamineus leaves. Extraction using aqueous solvent enabled a simultaneous extraction of both hydrophilic and lipophilic phenolic compounds.
S. F. Pang, M. M. Yusoff, J. Gimbun
doaj +1 more source
Flavonoids-Rich Orthosiphon stamineus Extract as New Candidate for Angiotensin I-Converting Enzyme Inhibition: A Molecular Docking Study [PDF]
, 2016 This study aims to evaluate the in vitro angiotensin-converting enzyme (ACE) inhibition activity of different extracts of Orthosiphon stamineus (OS) leaves and their main flavonoids, namely rosmarinic acid (RA), sinensetin (SIN), eupatorin (EUP) and 30-
Aisha, Abdalrahim F. A. +6 more
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Citrus phenylpropanoids and defence against pathogens. Part I: Metabolic profiling in elicited fruits [PDF]
, 2016 Penicillium spp. are among the major postharvest pathogens of citrus fruit. Induction of natural resistance in fruits constitutes one of the alternatives to chemical fungicides.
Ballester Frutos, Ana Rosa +4 more
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