Results 11 to 20 of about 1,893 (191)

Isolasi Sinensetin dari Kumis Kucing (Orthosiphon aristatus Blume miq.) Varietas Putih [PDF]

JPSCR: Journal of Pharmaceutical Science and Clinical Research, 2021
Kumis kucing mengandung metabolit sekunder sinensetin yang termasuk ke dalam golongan senyawa flavonoid. Sinensetin berpotensi sebagai agen antivirus dan imunomodulator.
Fahrauk Faramayuda, Soraya Riyanti, Adella Shindy Pratiwi, Totik Sri Mariani, Elfahmi Elfahmi, Sukrasno Sukrasno   +5 more
doaj   +2 more sources

Sinensetin protects against periodontitis through binding to Bach1 enhancing its ubiquitination degradation and improving oxidative stress [PDF]

International Journal of Oral Science
Periodontitis is a chronic inflammatory and immune reactive disease induced by the subgingival biofilm. The therapeutic effect for susceptible patients is often unsatisfactory due to excessive inflammatory response and oxidative stress.
Zhiyao Yuan, Junjie Li, Fuyu Xiao, Yu Wu, Zhiting Zhang, Jiahong Shi, Jun Qian, Xudong Wu, Fuhua Yan   +8 more
doaj   +4 more sources

Sinensetin suppresses influenza a virus-triggered inflammation through inhibition of NF-κB and MAPKs signalings [PDF]

BMC Complementary Medicine and Therapies, 2020
Background Human respiratory system infected with influenza A virus (IAV) elicited a robust pro-inflammatory response that resulted in severe illness and even death.
Jiashun Li, Xiang Jie, Xiaoli Liang, Ziyu Chen, Peifang Xie, Xiping Pan, Beixian Zhou, Jing Li   +7 more
doaj   +3 more sources

The Potential Role of Rosmarinic Acid and Sinensetin as α-Amylase Inhibitor: In Silico Study [PDF]

Journal of Pure and Applied Chemistry Research, 2019
The study of natural compound as α-amylase inhibitor has been a concern since the synthetic drugs for the management of type 2 diabetes mellitus have several side effects.
Hazna Noor Meidinna, Fatchiyah Fatchiyah   +1 more
doaj   +3 more sources

Sinensetin-Rich Fraction Solid Dispersion Inhibits Cancer Cell Cycle [PDF]

KnE Life Sciences, 2017
Drug development efforts to find new selective and safe drugs for cancer from natural resources are promising ones. The natural products are obtained in the multiple or single compounds. One of them is a sinensetin found in ethanol extract of Orthosiphon
Arifianti, Lusiana, Santosa, Mulja Hadi, Sukardiman, Sukardiman   +2 more
core   +5 more sources

Sinensetin regulates age-related sarcopenia in cultured primary thigh and calf muscle cells [PDF]

BMC Complementary and Alternative Medicine, 2019
Background Sarcopenia, the decline of skeletal muscle tissue attributed to primary aging is a major concern in older adults. Flavonoids might have potential benefits by modulating the regulation of satellite cells, thus preventing muscle loss. Sinensetin
Jin-A Kim, Seong Min Kim, Sang Eun Ha, Preethi Vetrivel, Venu Venkatarame Gowda Saralamma, Eun Hee Kim, Gon Sup Kim   +6 more
doaj   +3 more sources

VIRTUAL SEARCHING OF DUMMY TEMPLATE FOR SINENSETIN BASED ON 2D MOLECULAR SIMILARITY USING CHEMDB TOOL

Indonesian Journal of Chemistry, 2012
Sinensetin-like molecules have been searched virtually to find a dummy template for Molecular Imprinted Polymer (MIP) synthesis. The aim of this study is to find a novel adsorbent for Solid Phase Extraction (SPE) of sinensetin based on tailored method ...
Iqmal Tahir, Mohd Noor Ahmad, AKM Shafiqul Islam, Dachyar Arbain   +3 more
doaj   +4 more sources

Sinensetin serves as an AMPK activator to inhibit RANKL-induced osteoclastogenesis via osteoclast cytoskeleton reorganization [PDF]

Journal of Translational Medicine
Osteoporosis is a skeletal condition caused by an excess of osteoclasts, resulting in an imbalance in bone metabolism. Sinensetin (SIN), one of the main ingredients in citrus fruits, provides a variety of pharmacological properties, like antioxidant, but
Yijie Gao, Rui Zhou, Xixi Lin, Zhijuan Liu, Yuangang Su, Haoyu Lian, Bin Lin, Xiaofei Ding, Shijie Liao, Xiangde Li, Jinmin Zhao, Jiake Xu, Ren Xu, Qian Liu, Fangming Song   +14 more
doaj   +2 more sources

Utilizing network pharmacology and other tools to examine active components and mechanism of action of Magnolia officinalis rheum rhabarbarum decoction in treating Streptococcus pyogenes skin infections [PDF]

Bioresources and Bioprocessing
Infections caused by Streptococcus pyogenes and the growing threat of antibiotic resistance pose significant global health challenges. This study investigates the antibacterial properties of Magnolia officinalis Rheum rhabarbarum Decoction against ...
Yuanhao Wang, Xinrui Wang, Xueying Zhang, Mengyi Pan, Mingyang Sun, Zhiguo chen, Yingli Song   +6 more
doaj   +2 more sources

Enhancement and optimization of sinensetin extract from orthosiphon stamineus using supercrtitical carbon dioxide extraction [PDF]

Malaysian Journal of Analytical Science, 2018
Sinensetin is a rare valuable flavonoid compound that contains 5 methoxy groups attached on the flavone backbone. This compound is abundantly established in citrus peel and can also be found in medicinal herb, ‘misai kucing’.
Abdul Aziz, Ahmad Hazim, Che Yunus, Mohd. Azizi, Idham, Zuhaili, Lee, Nian Yian, Mohd. Hadzri, Hafizah, Mustapha, Ana Najwa, Rithwan, Fahim   +6 more
core   +3 more sources