Results 91 to 100 of about 32,538,527 (305)

Dual-well microfluidic technique for single cell isolation and long-term clonal culture

, 2023
[[abstract]]The clonal culture of single cells is widely used for studying cell dynamics and heterogeneity in vitro and producing monoclonal cell populations.
Yeh, CF;Chang, HC;Hsu, CH
core   +1 more source

A systematic overview of single-cell transcriptomics databases, their use cases, and limitations

Frontiers in Bioinformatics
Rapid advancements in high-throughput single-cell RNA-seq (scRNA-seq) technologies and experimental protocols have led to the generation of vast amounts of transcriptomic data that populates several online databases and repositories.
Mahnoor N. Gondal, Mahnoor N. Gondal, Saad Ur Rehman Shah, Arul M. Chinnaiyan, Arul M. Chinnaiyan, Arul M. Chinnaiyan, Arul M. Chinnaiyan, Arul M. Chinnaiyan, Arul M. Chinnaiyan, Marcin Cieslik, Marcin Cieslik, Marcin Cieslik, Marcin Cieslik   +12 more
doaj   +1 more source

Deep Learning in Single-cell Analysis

ACM Transactions on Intelligent Systems and Technology
Single-cell technologies are revolutionizing the entire field of biology. The large volumes of data generated by single-cell technologies are high dimensional, sparse, and heterogeneous and have complicated dependency structures, making analyses using conventional machine learning approaches challenging and impractical.
Dylan Molho, Jiayuan Ding, Wenzhuo Tang, Zhaoheng Li, Hongzhi Wen, Yixin Wang 0003, Julian Venegas, Wei Jin 0009, Renming Liu, Runze Su, Patrick Danaher, Robert Yang, Yu Leo Lei, Yuying Xie 0001, Jiliang Tang   +14 more
openaire   +2 more sources

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

Single-Cell-Derived Tumor-Sphere Formation and Drug-Resistance Assay Using an Integrated Microfluidics

, 2019
Considerable evidence points to cancer stem-like cells (CSCs) as responsible for promoting progression, metastasis, and drug resistance. Without damage to the cell biological properties, single-cell-derived tumor-sphere is encouraging options for CSCs ...
Jing Ding, Long Pang (457760), Long Pang, Jianglin Fan (448849), Yuxin Ge, Yuxin Ge (5988779), Shih-Kang Fan (733610), Jianglin Fan, Shih-Kang Fan, Jing Ding (32381)   +9 more
core   +1 more source

Single Cell Analysis of Human RAD18-Dependent DNA Post-Replication Repair by Alkaline Bromodeoxyuridine Comet Assay [PDF]

, 2013
Damage to DNA can block replication progression resulting in gaps in the newly synthesized DNA. Cells utilize a number of post-replication repair (PRR) mechanisms such as the RAD18 controlled translesion synthesis or template switching to overcome the ...
Himabindu Gali, Mórocz Mónika, Downes C. Stephen, Raskó István, Haracska Lajos, Downes, C. Stephen, Gali Himabindu, C Stephen Downes, Mórocz, Mónika, Lajos Haracska, Mónika Mórocz, Gali, Himabindu, Raskó, István, Haracska, Lajos, István Raskó   +14 more
core   +2 more sources

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

SINGLE CELL METABOLOMICS USING MASS SPECTROMETRY: DEVICES, METHODS AND APPLICATIONS [PDF]

, 2019
Cells are basic functional components of eukaryotic organisms containing rich biological and physiological information. To investigate the nature of cells, a variety of fundamental and mechanistic studies of the cell functions, cellular metabolisms ...
Liu, Renmeng
core  

Single cell analysis of transcriptional activation dynamics.

PLoS ONE, 2010
BackgroundGene activation is thought to occur through a series of temporally defined regulatory steps. However, this process has not been completely evaluated in single living mammalian cells.Methodology/principal findingsTo investigate the timing and ...
Ilona U Rafalska-Metcalf, Sara Lawrence Powers, Lucy M Joo, Gary LeRoy, Susan M Janicki   +4 more
doaj   +1 more source