Results 21 to 30 of about 5,714,705 (321)

The role of hemoglobin in nitric oxide transport in vascular system

open access: yesMedicine in Novel Technology and Devices, 2020
Nitric oxide (NO) plays a pivotal role in vascular homeostasis and its functions practice in a dose-dependent manner in which too high and too low NO concentration may both induce the development of cardiovascular diseases, which indicates the balance ...
Haoran Su   +4 more
doaj   +1 more source

Electrical Characterization and Analysis of Single Cells and Related Applications

open access: yesBiosensors, 2023
Biological parameters extracted from electrical signals from various body parts have been used for many years to analyze the human body and its behavior.
Weitao Zhu   +6 more
doaj   +1 more source

Single‐cell proteomic analysis

open access: yesWIREs Mechanisms of Disease, 2020
AbstractThe ability to comprehensively profile proteins in every individual cell of complex biological systems is crucial to advance our understanding of normal physiology and disease pathogenesis. Conventional bulk cell experiments mask the cell heterogeneity in the population, while the single‐cell imaging methods suffer from the limited multiplexing
Thai Pham   +3 more
openaire   +3 more sources

Microfluidic single‐cell multiomics analysis

open access: yesView, 2023
Cellular heterogeneity is essential to biological processes, such as embryonic development, cell differentiation, and the progression of disease. Recent years have seen the development of a variety of single‐cell multiomics technologies that systemically
Xing Xu   +8 more
doaj   +1 more source

Trajectory-based differential expression analysis for single-cell sequencing data [PDF]

open access: yes, 2020
Trajectory inference has radically enhanced single-cell RNA-seq research by enabling the study of dynamic changes in gene expression. Downstream of trajectory inference, it is vital to discover genes that are (i) associated with the lineages in the ...
Cannoodt, Robrecht   +7 more
core   +2 more sources

Microfluidic Compartmentalization Platforms for Single Cell Analysis

open access: yesBiosensors, 2022
Many cellular analytical technologies measure only the average response from a cell population with an assumption that a clonal population is homogenous.
Xuhao Luo   +3 more
doaj   +1 more source

An end-to-end software solution for the analysis of high-throughput single-cell migration data [PDF]

open access: yes, 2017
The systematic study of single-cell migration requires the availability of software for assisting data inspection, quality control and analysis. This is especially important for high-throughput experiments, where multiple biological conditions are tested
Ampe, Christophe   +5 more
core   +2 more sources

Microfluidics-Based Single-Cell Research for Intercellular Interaction

open access: yesFrontiers in Cell and Developmental Biology, 2021
Intercellular interaction between cell–cell and cell–ECM is critical to numerous biology and medical studies, such as stem cell differentiation, immunotherapy and tissue engineering. Traditional methods employed for delving into intercellular interaction
Long Pang   +10 more
doaj   +1 more source

EpiScanpy: integrated single-cell epigenomic analysis [PDF]

open access: yesNature Communications, 2021
Abstract EpiScanpy is a toolkit for the analysis of single-cell epigenomic data, namely single-cell DNA methylation and single-cell ATAC-seq data. To address the modality specific challenges from epigenomics data, epiScanpy quantifies the epigenome using multiple feature space constructions and builds a nearest neighbour graph using ...
Anna Danese   +5 more
openaire   +6 more sources

Single-cell western blotting. [PDF]

open access: yes, 2014
To measure cell-to-cell variation in protein-mediated functions, we developed an approach to conduct ∼10(3) concurrent single-cell western blots (scWesterns) in ∼4 h.
Herr, Amy E   +5 more
core   +2 more sources

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