Results 71 to 80 of about 9,923,505 (317)

Unheard and Under‐Supported: Health‐Related Quality of Life in Children, Adolescents, and Young Adults With Sickle Cell Disease

open access: yesPediatric Blood &Cancer, EarlyView.
Abstract Background Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy affecting millions of individuals worldwide. The clinical expression and psychosocial burden of SCD vary widely across geographical, cultural, and healthcare system contexts, underscoring the need for setting‐specific approaches to assessment.
Desiré Fantasia   +7 more
wiley   +1 more source

ScRNAPip: A systematic and dynamic pipeline for single‐cell RNA sequencing analysis

open access: yesiMeta, 2023
With the advancement of sequencing technology, cell separation, and whole‐genome amplification techniques, single cell technology for genome sequencing is emerging gradually.
Limin Xu   +9 more
doaj   +1 more source

Single-cell analysis highlights differences in druggable pathways underlying adaptive or fibrotic kidney regeneration

open access: yesNature Communications, 2022
The kidney has tremendous capacity to repair after acute injury, however, pathways guiding adaptive and fibrotic repair are poorly understood. We developed a model of adaptive and fibrotic kidney regeneration by titrating ischemic injury dose.
Michael S. Balzer   +11 more
semanticscholar   +1 more source

Chemical analysis of a single basic cell of porous anodic aluminium oxide templates [PDF]

open access: yes, 2010
We prepared anodic aluminium oxide (AAO) templates with “honeycomb” geometry, i.e. hexagonally ordered circular pores. The structures were extensively studied and characterized by EPMA coupled with FEG-SEM and FEG-TEM coupled with EDX at meso and ...
Arurault, Laurent   +2 more
core   +2 more sources

Effects of Cancer Treatment on Somatosensory and Nociceptive Processing in Children and Adolescents: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Chemotherapy‐induced peripheral neuropathy remains a major complication in pediatric cancer, with disrupted somatosensory and nociceptive processing being a key aspect. This review synthesizes empirical studies on alterations in somatosensory and nociceptive processing in children and adolescents with cancer.
Julia Schweiger   +4 more
wiley   +1 more source

Evaluating PSA dynamics for predicting androgen deprivation failure with a patient specific prostate cancer model

open access: yesnpj Systems Biology and Applications
Prostate cancer is the second leading cause of cancer-related death among American men, with a new diagnosis made every 2 min in the United States. Advanced cases are commonly treated with androgen deprivation therapy (ADT).
Shengchao Zhao   +7 more
doaj   +1 more source

Revisiting single cell analysis in forensic science

open access: yesScientific Reports, 2021
Forensic science has yet to take full advantage of single cell analysis. Its greatest benefit is the ability to alleviate the challenges associated with DNA mixture analysis, which remains a significant hurdle in forensic science.
Davis R. L. Watkins   +3 more
doaj   +1 more source

Single‐Cell Analysis Using Droplet Microfluidics [PDF]

open access: yesAdvanced Biosystems, 2019
AbstractDroplet microfluidics has revolutionized the study of single cells. The ability to compartmentalize cells within picoliter droplets in microfluidic devices has opened up a wide range of strategies to extract information at the genomic, transcriptomic, proteomic, or metabolomic level from large numbers of individual cells. Studying the different
Kinga Matuła   +2 more
openaire   +3 more sources

High-dimensional single-cell analysis of human natural killer cell heterogeneity

open access: yesNature Immunology
Natural killer (NK) cells are innate lymphoid cells (ILCs) contributing to immune responses to microbes and tumors. Historically, their classification hinged on a limited array of surface protein markers.
Lucas Rebuffet   +26 more
semanticscholar   +1 more source

Current best practices in single‐cell RNA‐seq analysis: a tutorial

open access: yesMolecular Systems Biology, 2019
Single‐cell RNA‐seq has enabled gene expression to be studied at an unprecedented resolution. The promise of this technology is attracting a growing user base for single‐cell analysis methods. As more analysis tools are becoming available, it is becoming
Malte D. Luecken, Fabian J Theis
semanticscholar   +1 more source

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