Results 81 to 90 of about 1,731,641 (260)

Single Cell Apoptosis Imaging and Gene Expression Analysis

open access: yesProceedings of The 7th International Multidisciplinary Conference on Optofluidics 2017, 2017
Single cell analysis is a powerful tool to unveil cell heterogeneity, which may play a important role in series events in cancer progression, such as tumor initiation, metastasis and clinical chemotherapy resistance. To profile subtle biological variations at individual cell level, methods that allows single cell imaging and corresponding gene ...
openaire   +1 more source

Sterol gene expression in Arabidopsis [PDF]

open access: yes, 2009
Sterols are recognized as playing vital roles in plant development, as has been demonstrated from mutational studies. The study of the hydra mutants of Arabidopsis provides new tools to dissect sterol function in development at the molecular genetic ...
Liu, Dongbin
core  

Integrated signaling pathway and gene expression regulatory model to dissect dynamics of Escherichia coli challenged mammary epithelial cells [PDF]

open access: yes, 2014
Cells transform external stimuli, through the activation of signaling pathways, which in turn activate gene regulatory networks, in gene expression. As more omics data are generated from experiments, eliciting the integrated relationship between the ...
den Breems, NY   +4 more
core   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Single-Cell Gene Expression Analysis Revealed Immune Cell Signatures of Delta COVID-19. [PDF]

open access: yesCells, 2022
Shaymardanov AM   +19 more
europepmc   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal [PDF]

open access: yes, 2012
Drosophila neuroblasts (NBs) have emerged as a model for stem cell biology that is ideal for genetic analysis but is limited by the lack of cell-type-specific gene expression data.
Jonas Steinmann   +17 more
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

A systems biology design and implementation of novel bioinformatics software tools for high throughput gene expression analysis

open access: yes, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Microarray technology has revolutionized the field of molecular biology by offering an efficient and cost effective platform for the simultaneous ...
Khan, Mohsin Amir Faiz
core  

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