Results 201 to 210 of about 853,175 (263)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Efficacy and Safety of Regorafenib with or without Immune Checkpoint Inhibitors as Second-Line Treatment for Advanced Hepatocellular Carcinoma: A Systematic Review and Arm-Level Synthesis of Real-World Comparative Cohorts. [PDF]

Onco Targets Ther
Yu X, Zan H, Deng W, He R.
europepmc   +1 more source

Automated ROI detection allows rapid quantification of synaptic activity across tens of thousands of synapses in cell culture. [PDF]

Front Synaptic Neurosci
Begley JC, Prüss H, Turko P, Dean C.
europepmc   +1 more source

Drug- and patient-specific neurological risk profiles of α1-adrenergic blockers: evidence from FAERS and external validation in JADER. [PDF]

Ther Adv Drug Saf
Hai X, Huang L.
europepmc   +1 more source

Effect of Remimazolam on Postoperative Delirium in Surgical ICU Patients: A Single-Center Prospective Cohort Study. [PDF]

Crit Care Res Pract
Hong J, Zhao C, Lin L.
europepmc   +1 more source

Nanopore Label-Free Monitoring of B-DNA and Z-DNA Conformational Transition in Real Time. [PDF]

ACS Nano
Zheng H, Munusamy S, Kong J, Kanaherarachchi A, Zhou S, Chen J, Jahani R, Guan X.   +7 more
europepmc   +1 more source

Humidity may amplify the temperature-related health risks in the context of climate change. [PDF]

Sci Rep
He Y, Dong W, Zhao L, Wang H, Cai W, Liu Z, Lin H, Ma W, Huang C.   +8 more
europepmc   +1 more source

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Single-event effects on optical transceiver

2018 IEEE International Reliability Physics Symposium (IRPS), 2018
All communications systems use optical modules to achieve data transfer speeds in the 10's of GBPS range. With increasing reliance on communication systems, the impact of soft errors in optical transceiver modules has become a primary concern for system performance.
Kurt J. Lezon, Shi-Jie Wen, Y.-F. Dan, Richard Wong, Bharat L. Bhuva   +4 more
openaire   +1 more source