Results 11 to 20 of about 367,917 (307)
Single-stranded DNA and RNA origami [PDF]
Science, 2017 Large origami from a single strand Nanostructures created by origami-like folding of nucleic acids are usually formed by base-pairing interactions between multiple strands. Han et al. show that large origami (up to 10,000 nucleotides for DNA and 6000 nucleotides for RNA) can be created in simple shapes ...
Dongran Han +11 more
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Towards quantitative viromics for both double-stranded and single-stranded DNA viruses [PDF]
PeerJ, 2016 Background Viruses strongly influence microbial population dynamics and ecosystem functions. However, our ability to quantitatively evaluate those viral impacts is limited to the few cultivated viruses and double-stranded DNA (dsDNA) viral genomes ...
Simon Roux +8 more
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Three-dimensional modeling of single stranded DNA hairpins for aptamer-based biosensors
Scientific Reports, 2017 Aptamers consist of short oligonucleotides that bind specific targets. They provide advantages over antibodies, including robustness, low cost, and reusability.
Iman Jeddi, Leonor Saiz
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Single-stranded circular DNA theranostics
Theranostics, 2022 The past decade has witnessed the blossom of nucleic acid therapeutics and diagnostics (theranostics). Unlike conventional small molecule medicines or protein biologics, nucleic acid theranostics have characteristic features such as the intrinsic ability as "information drugs" to code and execute genetic and theranostic information, ready ...
Shen, Tingting +4 more
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Single Stranded DNA Translocases can Push Single Stranded DNA Binding Proteins along Single Stranded DNA [PDF]
Biophysical Journal, 2016 Single-stranded (ss) DNA binding proteins (SSBs) protect ssDNA intermediates during genome maintenance. These SSBs must eventually be displaced or reorganized and one potential mechanism for reorganization is pushing of the SSB along the DNA by ssDNA translocases (ATP-dependent motors).
Sokoloski, Joshua E. +3 more
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Electrochemical Science Advances, 2022 The α‐hemolysin nanopore has attracted much attention as a tool for the single‐molecule analysis of DNA due to its potential as an ultra‐sensitive, specific, and label‐free sensing technique. The vast majority of DNA sensing research with the α‐hemolysin
Shekemi Denuga +3 more
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Cooperativity-Dependent Folding of Single-Stranded DNA
Physical Review X, 2021 The folding of biological macromolecules is a fundamental process of which we lack a full comprehension. Mostly studied in proteins and RNA, single-stranded DNA (ssDNA) also folds, at physiological salt conditions, by forming nonspecific secondary ...
X. Viader-Godoy +4 more
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CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA
Cell Research, 2018 Dear Editor, The CRISPR-associated protein Cas12a (previously known as Cpf1), which is an endonuclease from the type V-A CRISPR system, has been applied in both in vivo genome editing and in vitro DNA assembly.
Shiyuan Li +5 more
semanticscholar +1 more source
Nature Methods, 2020 Transcription is a highly dynamic process that generates single-stranded DNA (ssDNA) in the genome as ‘transcription bubbles’. Here we describe a kethoxal-assisted single-stranded DNA sequencing (KAS-seq) approach, based on the fast and specific reaction
Tong Wu +3 more
semanticscholar +1 more source
Continuous Approximation for Interaction Energy Transfer of DNA through Lipid Bilayers
Discrete Dynamics in Nature and Society, 2018 In this study the interaction energies for single-stranded DNA and double-stranded DNA molecules with a lipid bilayer are investigated. The 6-12 Lennard-Jones potential and continuous approximation are used to derive analytical expressions for these ...
Mansoor H. Alshehri
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