Results 11 to 20 of about 367,400 (264)
Single-stranded DNA and RNA origami [PDF]
Science, 2017 Large origami from a single strand Nanostructures created by origami-like folding of nucleic acids are usually formed by base-pairing interactions between multiple strands. Han et al. show that large origami (up to 10,000 nucleotides for DNA and 6000 nucleotides for RNA) can be created in simple shapes ...
Dongran Han +11 more
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Single-stranded circular DNA theranostics
Theranostics, 2022 The past decade has witnessed the blossom of nucleic acid therapeutics and diagnostics (theranostics). Unlike conventional small molecule medicines or protein biologics, nucleic acid theranostics have characteristic features such as the intrinsic ability as "information drugs" to code and execute genetic and theranostic information, ready ...
Shen, Tingting +4 more
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Single Stranded DNA Translocases can Push Single Stranded DNA Binding Proteins along Single Stranded DNA [PDF]
Biophysical Journal, 2016 Single-stranded (ss) DNA binding proteins (SSBs) protect ssDNA intermediates during genome maintenance. These SSBs must eventually be displaced or reorganized and one potential mechanism for reorganization is pushing of the SSB along the DNA by ssDNA translocases (ATP-dependent motors).
Sokoloski, Joshua E. +3 more
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RPA shields inherited DNA lesions for post-mitotic DNA synthesis
Nature Communications, 2021 Single-stranded DNA during DNA replication and repair in S/G2 needs protection by replication protein A (RPA). Here the authors reveal that RPA also shields inherited single-stranded DNA in G1, representing replication remnants from the previous cell ...
Aleksandra Lezaja +5 more
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Electrochemical Science Advances, 2022 The α‐hemolysin nanopore has attracted much attention as a tool for the single‐molecule analysis of DNA due to its potential as an ultra‐sensitive, specific, and label‐free sensing technique. The vast majority of DNA sensing research with the α‐hemolysin
Shekemi Denuga +3 more
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Cooperativity-Dependent Folding of Single-Stranded DNA
Physical Review X, 2021 The folding of biological macromolecules is a fundamental process of which we lack a full comprehension. Mostly studied in proteins and RNA, single-stranded DNA (ssDNA) also folds, at physiological salt conditions, by forming nonspecific secondary ...
X. Viader-Godoy +4 more
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Continuous Approximation for Interaction Energy Transfer of DNA through Lipid Bilayers
Discrete Dynamics in Nature and Society, 2018 In this study the interaction energies for single-stranded DNA and double-stranded DNA molecules with a lipid bilayer are investigated. The 6-12 Lennard-Jones potential and continuous approximation are used to derive analytical expressions for these ...
Mansoor H. Alshehri
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Proceedings, 2020 Single-stranded DNA binding proteins (SSBs) bind to single-stranded DNA in a sequence-independent manner to prevent formation of secondary structures and protect DNA from nuclease degradation.
Olesia Werbowy +9 more
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Nanomaterials, 2013 Separation of short single- and double-stranded DNA typically requires gel electrophoresis followed by DNA extraction, which is a time consuming process.
Po-Jung Jimmy Huang, Juewen Liu
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Variable termination sites of DNA polymerases encountering a DNA-protein cross-link. [PDF]
PLoS ONE, 2018 DNA-protein cross-links (DPCs) are important DNA lesions induced by endogenous crosslinking agents such as formaldehyde or acetaldehyde, as well as ionizing radiation, cancer chemotherapeutic drugs, and abortive action of some enzymes.
Anna V Yudkina +2 more
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