Results 31 to 40 of about 367,917 (307)
Nature Communications, 2019 Single-stranded (ss) DNA viruses are a major component of the earth virome. In particular, the circular, Rep-encoding ssDNA (CRESS-DNA) viruses show high diversity and abundance in various habitats.
Darius Kazlauskas +3 more
semanticscholar +1 more source
Hybrids of Nucleic Acids and Carbon Nanotubes for Nanobiotechnology
Nanomaterials, 2015 Recent progress in the combination of nucleic acids and carbon nanotubes (CNTs) has been briefly reviewed here. Since discovering the hybridization phenomenon of DNA molecules and CNTs in 2003, a large amount of fundamental and applied research has been ...
Kazuo Umemura
doaj +1 more source
A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA
Nature Communications, 2018 Replication Protein A (RPA), the major eukaryotic single stranded DNA-binding protein, binds to exposed ssDNA to protect it from nucleases, participates in a myriad of nucleic acid transactions and coordinates the recruitment of other important players ...
L. Yates +8 more
semanticscholar +1 more source
Seamless Insert-Plasmid Assembly at High Efficiency and Low Cost. [PDF]
PLoS ONE, 2016 Seamless cloning methods, such as co-transformation cloning, sequence- and ligation-independent cloning (SLIC) or the Gibson assembly, are essential tools for the precise construction of plasmids.
Roger M Benoit +5 more
doaj +1 more source
Folding of single‐stranded DNA on the histone octamer [PDF]
FEBS Letters, 1985 A complex between the single‐stranded DNA of the bacteriophage M13 and the histone octamer was analyzed by electron microscopy, low‐angle X‐ray diffraction and nuclease analysis. The morphology and the diffraction pattern of the complex strongly resemble those of the nucleosome.
Caffarelli E, Leoni L, Savino M
openaire +3 more sources
Coordinated Binding of Single-Stranded and Double-Stranded DNA by UvsX Recombinase. [PDF]
PLoS ONE, 2013 Homologous recombination is important for the error-free repair of DNA double-strand breaks and for replication fork restart. Recombinases of the RecA/Rad51 family perform the central catalytic role in this process.
Robyn L Maher, Scott W Morrical
doaj +1 more source
Complex shapes self-assembled from single-stranded DNA tiles
Nature, 2012 Programmed self-assembly of strands of nucleic acid has proved highly effective for creating a wide range of structures with desired shapes. A particularly successful implementation is DNA origami, in which a long scaffold strand is folded by hundreds of
Bryan Wei, Mingjie Dai, P. Yin
semanticscholar +1 more source
BMC Genomics, 2019 Background Cell-free DNA (cfDNA), present in circulating blood plasma, contains information about prenatal health, organ transplant reception, and cancer presence and progression.
Christopher J. Troll +8 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Insertional Mutagenesis by CRISPR/Cas9 Ribonucleoprotein Gene Editing in Cells Targeted for Point Mutation Repair Directed by Short Single-Stranded DNA Oligonucleotides. [PDF]
PLoS ONE, 2017 CRISPR/Cas9 and single-stranded DNA oligonucleotides (ssODNs) have been used to direct the repair of a single base mutation in human genes. Here, we examine a method designed to increase the precision of RNA guided genome editing in human cells by ...
Natalia Rivera-Torres +4 more
doaj +1 more source