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Single-Stranded DNA Family Shuffling
2004Publisher Summary This chapter examines the various aspects of single-stranded DNA family shuffling. DNA shuffling is a technique that allows accelerated and directed protein evolution in vitro . This technique has been shown to be powerful in combining independently isolated mutations of a gene into a single progeny. By using the sense strand ssDNA
Osamu, Kagami +2 more
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Single-Stranded DNA Phage Origins
1988Since the rediscovery of bacteriophage o X174 in the 1950 s by Robert Sinsheimer (1959), the single-stranded DNA phages have been widely used as model systems in molecular biology. o X174 can be considered as their “ godfather. ” The single-stranded DNA bacteriophages are divided into two classes based on the morphology of their representatives, either
P D, Baas, H S, Jansz
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DNA single-strand breaks and neurodegeneration
DNA Repair, 2004The association of human genetic disorders with defects in the DNA damage response is well established. Most of the major DNA repair pathways are represented by diseases in which that pathway is absent or impaired, including those responsible for repairing DNA double-strand breaks.
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Stretching single stranded DNA
Soft Matter, 2011Recently, single molecule force spectroscopy experiments provided much important information about the elastic properties of a single stranded DNA. Theoretical efforts, which followed these experiments could not provide satisfactory explanation for some of the observed results.
Sanjay Kumar, Garima Mishra
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Single‐stranded DNA‐containing bacteriophages
BioEssays, 1986AbstractRoots presents articles on major discoveries that laid the basis for contemporary molecular and cellular biology. In this article, Norton D. Zinder reviews the first findings about the single‐stranded DNA‐containing bacteriophages and what is known today about the genetics and molecular biology of these phages.
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Imaging of Single-Stranded DNA
AIP Conference Proceedings, 1991Uncoated single‐strands DNA mixed with BAC (benzyldimethylalkylammonium chloride) were deposited on gold substrates and imaged in air with Scanning Tunneling Microscopy (STM). Constant‐current and gap‐modulated STM images showed that most of the DNA filaments tend to form aggregates where it is difficult to distinguish among the different nucleotides ...
Cricenti A +4 more
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Selection of single-stranded DNA molecules that bind and inhibit human thrombin
Nature, 1992Louis C. Bock +4 more
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A very small porcine virus with circular single-stranded DNA
Nature, 1982I. Tischer +3 more
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