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Single-Stranded DNA Family Shuffling

2004
Publisher Summary This chapter examines the various aspects of single-stranded DNA family shuffling. DNA shuffling is a technique that allows accelerated and directed protein evolution in vitro . This technique has been shown to be powerful in combining independently isolated mutations of a gene into a single progeny. By using the sense strand ssDNA
Osamu, Kagami   +2 more
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Single-Stranded DNA Phage Origins

1988
Since the rediscovery of bacteriophage o X174 in the 1950 s by Robert Sinsheimer (1959), the single-stranded DNA phages have been widely used as model systems in molecular biology. o X174 can be considered as their “ godfather. ” The single-stranded DNA bacteriophages are divided into two classes based on the morphology of their representatives, either
P D, Baas, H S, Jansz
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DNA single-strand breaks and neurodegeneration

DNA Repair, 2004
The association of human genetic disorders with defects in the DNA damage response is well established. Most of the major DNA repair pathways are represented by diseases in which that pathway is absent or impaired, including those responsible for repairing DNA double-strand breaks.
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Stretching single stranded DNA

Soft Matter, 2011
Recently, single molecule force spectroscopy experiments provided much important information about the elastic properties of a single stranded DNA. Theoretical efforts, which followed these experiments could not provide satisfactory explanation for some of the observed results.
Sanjay Kumar, Garima Mishra
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Single‐stranded DNA‐containing bacteriophages

BioEssays, 1986
AbstractRoots presents articles on major discoveries that laid the basis for contemporary molecular and cellular biology. In this article, Norton D. Zinder reviews the first findings about the single‐stranded DNA‐containing bacteriophages and what is known today about the genetics and molecular biology of these phages.
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Imaging of Single-Stranded DNA

AIP Conference Proceedings, 1991
Uncoated single‐strands DNA mixed with BAC (benzyldimethylalkylammonium chloride) were deposited on gold substrates and imaged in air with Scanning Tunneling Microscopy (STM). Constant‐current and gap‐modulated STM images showed that most of the DNA filaments tend to form aggregates where it is difficult to distinguish among the different nucleotides ...
Cricenti A   +4 more
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Selection of single-stranded DNA molecules that bind and inhibit human thrombin

Nature, 1992
Louis C. Bock   +4 more
semanticscholar   +1 more source

A very small porcine virus with circular single-stranded DNA

Nature, 1982
I. Tischer   +3 more
semanticscholar   +1 more source

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