Results 181 to 190 of about 507,473 (216)

GTPase cycle and ER membrane regulate cargo handover during cotranslational protein targeting. [PDF]

Sci Adv
Qian R, Gora RJ, Chung S, Lee JH, Chandrasekar S, Wang MF, Weiss S, Shan SO.   +7 more
europepmc   +1 more source

Accelerated Discovery of Topological Spin Phase Diagrams in CrSBr Magnets Via High‐Throughput Optimization

Advanced Functional Materials, EarlyView.
Here, we develop a high‐throughput algorithm that accelerates the elucidation of phase diagrams of topological spin textures using limited computational resources at high numerical accuracy. Applying this framework to the van der Waals magnet CrSBr, we unveiled a hierarchy of previously unknown topological textures (domain‐wall bimerons, bimeron chains,
Andrew Lyall, Mohammad H. Badarneh, Cristian Bonato, Rebecca Cheung, Elton J. G. Santos   +4 more
wiley   +1 more source

Insights into how JIP3 and JIP4 adaptor proteins relieve the auto-inhibited form of the kinesin-1 motor. [PDF]

J Biol Chem
Vilela F, Chenon M, Campanacci V, Alik A, Velours C, Andreani J, Llinas P, Ménétrey J.   +7 more
europepmc   +1 more source

Protein‐Nanoarchitectures for Low‐Field Intracellular Electro‐Immunomodulation

Advanced Functional Materials, EarlyView.
DHQ‐SDH‐mediated binding of AuNPs drives the formation of interconnected, chain‐like nanoarchitectures with enhanced electrical conductivity. These conductive assemblies undergo macrophage uptake and enable low‐field electrical stimulation, promoting M1‐to‐M2 phenotypic switching with decreased iNOS and increased CD206 expression. Such protein‐mediated
Viktoriya Pakharenko, Djanira Rodrigues Negrão, Tanmay Gupta, Robert Jeng, Otavio Augusto Titton Dias, Maia Jaffer‐Diaz, Dinesh Christendat, Mohini Sain   +7 more
wiley   +1 more source

Photoinduced Charge Separation in Single‐Component Squaraine Films: The Key Role of Electrostatic Disorder

Advanced Functional Materials, EarlyView.
ABSTRACT Neat films of organic dyes are an interesting technological platform for solar cells and photodetectors. Recently, the conventional biphasic bulk‐heterojunction paradigm for photoinduced charge separation was challenged by the observation that charge carriers can be photogenerated in single‐component materials. A comprehensive experimental and
Davide Giavazzi, João Pedro Ferreira Assunção, Michael Bauer, Matthias Diethelm, Wei‐Hsu Hu, Mohammad Jafarpour, Roland Widmer, Antonia Neels, Dimitrios Sapalidis, Bruno F. B. Silva, Roland Hany, Frank Nüesch, Anna Painelli   +12 more
wiley   +1 more source

Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces

Advanced Functional Materials, EarlyView.
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng, TzuChun Chung, Katpady Akhil Tantry, Siyu Wu, Jing Tian, Yunqi Cui, Lanyu Li, Yongzan Zhou, Zhilei Zhang, Zhe Su, Gaili Cao, Kun‐Wei Yeh, Ruipeng Li, Xianghui Xiao, Adam F. G. Leontowich, Yuan‐Yu Hsueh, Zhao Pan, Kam C. Tam, Badri Narayanan, Song Li, Yimin. A. Wu   +20 more
wiley   +1 more source

Small Molecule Stabilization of Diverse Amyloidogenic Immunoglobulin Light Chains Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry. [PDF]

J Mol Biol
Peterle D, Yan NL, Klimtchuk ES, Srinivasu BY, Brusic V, Rhoades D, Wales TE, Gursky O, Kelly JW, Kelly JW, Engen JR, Morgan GJ.   +11 more
europepmc   +1 more source

Trans-interface coupling in the tetrameric enzyme underlies allosteric control in <i>Escherichia coli</i> biosynthetic threonine deaminase. [PDF]

J Struct Biol X
Khodi S, Yekeen AA, Liu H, Chen Q.
europepmc   +1 more source

Multimerization of a rationally designed nanobody for enhanced avidity toward Aβ42 oligomers. [PDF]

Protein Sci
Nowinska M, Suh E, Mogilevsky C, Vendruscolo M.   +3 more
europepmc   +1 more source

BA-ARAP-NMA: A Local Geometry Control Nonlinear Normal-Mode Analysis Method. [PDF]

Biology (Basel)
Zhang Z, Liu D, Yu H, Ma LZ.
europepmc   +1 more source