Results 121 to 130 of about 311,819 (318)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
, 2005 Doutoramento em Ciência e Engenharia de MateriaisImpulsionado pelo interesse em conhecer as propriedades intrínsecas dos compostos SrBi2Ta2O9 (SBT) e SrBi2Nb2O9 (SBN) que se apresentam como os materiais mais promissores para substituir o titanato de ...
Amorín González, Harvey
core
, 2019 Understanding the conformation effect on force-induced melting is important for developing advanced semicrystalline polymer materials. Here, two types of polymer single crystals, polycaprolactone (zigzag conformation) and poly(l-lactic acid) (helical ...
Xiujuan Lyu (5353424) +6 more
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Elastocaloric effect in Ni50Fe19Ga27Co4 single crystals
, 2015 The elastocaloric effect of the [001](P), and [111](P) orientated (subscript P represents the parent phase) Ni50Fe19Ga27Co4 (at.%) single crystals exhibiting first-order martensitic transformations have been studied at temperatures of 298-448 K under ...
Xiao, Fei +3 more
core
We report the growth of YTiO3 single crystals using different starting materials with the nominal compositions, (1) stoichiometric YTiO3; (2) oxygen deficient YTiO2.925; (3) oxygen deficient YTiO2.85, and different atmospheres, (1) 97%Ar/3%H2; (2) Ar; (3)
David Wenhua Bi +5 more
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Modelling evolution of anisotropy in metals using crystal plasticity [PDF]
, 2013 Many metals used in modern engineering exhibit anisotropy. A common assumption when modelling anisotropic metals is that the level of anisotropy is fixed throughout the calculation. As it is well understood that processes such as cold rolling, forging
Chaloupka, Ondrej
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source