Results 101 to 110 of about 810,857 (303)

Influence of redox cyclers on thiol oxidation in the presence of nanoparticles

Біофізичний вісник
Background: An increase in metabolic rate interconnected with oxidative imbalance are major features of tumor process. Higher ROS (reactive oxygen species) levels make tumor cells more sensitive to oxidative stress compared to normal cells.
Н. С. Кавок, Г. В. Дудецька, В. В. Семінько, П. О. Максимчук, В. К. Клочков, Ю. Г. Кот, Ю. В. Нікітченко, O. O. Сєдих   +7 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Manufacturing technology for flexible thermoresistors on polyimide base

Технологія та конструювання в електронній апаратурі, 2013
The article proposes the manufacturing technology for flexible thermoresistors on polyimide film and analyzes their advantages in relation to other temperature sensors.
D. A. Dinev, V. D. Zhora, N. N. Grigoryeva, V. P. Grunyanskaya   +3 more
doaj  

The regioselective synthesis of spirooxindolo pyrrolidines and pyrrolizidines via three-component reactions of acrylamides and aroylacrylic acids with isatins and α-amino acids

Beilstein Journal of Organic Chemistry, 2014
The regioselective three-component condensation of azomethine ylides derived from isatins and α-amino acids with acrylamides or aroylacrylic acids as dipolarophiles has been realized through a one-pot 1,3-dipolar cycloaddition protocol.
Tatyana L. Pavlovskaya, Fedor G. Yaremenko, Victoria V. Lipson, Svetlana V. Shishkina, Oleg V. Shishkin, Vladimir I. Musatov, Alexander S. Karpenko   +6 more
doaj   +1 more source

Effect of electron irradiation on the optical properties of nanocrystalline SiC films on single crystal Al2O3 substrates

Tekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2017
It was studied the effect of irradiation with high-energy (10 MeV) electrons on the optical properties of nanocrystalline carbide film system silicon / sapphire substrates in a wide range of fluences of 5·1014 to 2·1020 cm–2 and subsequent annealing in ...
O. V. Semenov, A. V. Lopin, V. N. Boriskin   +2 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Low Molecular Weight Supramolecular Allobetuline-, Cyclohexanol-, or Undecanol-Appended 1,2,3-Triazole-Based Gelators: Synthesis and Molecular Dynamics Simulation Study

SynOpen, 2023
Victoria Lipson, Oleg Zhikol, Svetlana Shishkina, Alexander Semenenko, Karina Kulyk, Pavel Mateychenko, Vladimir Musatov, Alexander Mazepa, Vladimir Vakula, Alexander Borisov, Alexander Kyrychenko   +10 more
doaj   +1 more source

Er,Yb:Ca3RE2(BO3)4 (RE=Y, Gd) – Novel 1.5 μm Laser Crystals

Приборы и методы измерений, 2019
The search for new crystalline host materials for the usage in lasers emitting in the eye-safe spectral range of 1.5–1.6 µm is an important task. The aim of this work was to study the growth technique, spectroscopic properties and laser characteristics ...
K. N. Gorbachenya, R. V. Deineka, V. E. Kisel, A. S. Yasukevich, A. N. Shekhovtsov, M. V. Kosmyna, N. V. Kuleshov   +6 more
doaj   +1 more source

Growth, Characterization, Vortex Pinning and Vortex Flow Properties of Single Crystals of Iron Chalcogenide Superconductor FeCr$_{0.02}$Se

, 2013
We report the growth and characterization of single crystals of iron chalcogenide superconductor FeCr$_{0.02}$Se. There is an enhancement of the superconducting transition temperature (T$_{\rm c}$) as compared to the T$_{\rm c}$ of the single crystals of
Thakur, Ajay D., Tomy, C. V., Yadav, Anil K.   +2 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source