Results 91 to 100 of about 810,857 (303)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

In water multicomponent synthesis of low-molecular-mass 4,7-dihydrotetrazolo[1,5-a]pyrimidines

open access: yesBeilstein Journal of Organic Chemistry, 2019
The three-component reaction of 5-aminotetrazole with aliphatic aldehydes (formaldehyde, acetaldehyde) and acetoacetic ester derivatives in water under microwave irradiation leads to the selective formation of 4,7-dihydrotetrazolo[1,5-a]pyrimidine ...
Irina G. Tkachenko   +8 more
doaj   +1 more source

The estimation of coherence length for electron-doped superconductor Nd$_{2-x}$Ce$_x$CuO$_{4+\delta}$

open access: yes, 2010
Results of low-temperature upper critical field measurements for Nd$_{2-x}$Ce$_x$CuO$_{4+\delta}$ single crystals with various $x$ and nonstoichiometric disorder ($\delta$) are presented.
A. A. Ivanov   +6 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Emergence of Large-Scale Magnetic-Vortices Structures by Small-Scale Helicity in Stratified Magnetized Plasma

open access: yesEast European Journal of Physics
In this paper, a new type of instability is identified, leading to the generation of vortex motions and magnetic fields in a plasma layer with a constant temperature gradient, subjected to uniform gravity and a vertical magnetic field.
Michael I. Kopp, Volodymyr V. Yanovsky
doaj   +1 more source

Method for the preparation of inorganic single crystal and polycrystalline electronic materials [PDF]

open access: yes, 1969
Large area, semiconductor crystals selected from group 3-5 compounds and alloys are provided for semiconductor device fabrication by the use of a selective etching operation which completely removes the substrate on which the desired crystal was ...
Groves, W. O.
core   +1 more source

Physical properties of EuPd2As2 single crystals

open access: yes, 2014
The physical properties of self-flux grown EuPd2As2 single crystals have been investigated by magnetization M, magnetic susceptibility chi, specific heat Cp, and electrical resistivity rho measurements versus temperature T and magnetic field H.
Anand, V. K., Johnston, D. C.
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Single-crystal to single-crystal reactions [PDF]

open access: yesActa Crystallographica Section A Foundations of Crystallography, 2005
C. Hu, U. Englert
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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