Results 101 to 110 of about 828,653 (197)

Single domain antibodies. [PDF]

Lancet (London, England), 1990
openaire   +4 more sources

TEMPRO: nanobody melting temperature estimation model using protein embeddings

Scientific Reports
Single-domain antibodies (sdAbs) or nanobodies have received widespread attention due to their small size (~ 15 kDa) and diverse applications in bio-derived therapeutics.
Jerome Anthony E. Alvarez, Scott N. Dean
doaj   +1 more source

Applications and challenges in designing VHH-based bispecific antibodies: leveraging machine learning solutions

mAbs
The development of bispecific antibodies that bind at least two different targets relies on bringing together multiple binding domains with different binding properties and biophysical characteristics to produce a drug-like therapeutic.
Michael Mullin, James McClory, Winston Haynes, Justin Grace, Nathan Robertson, Gino van Heeke   +5 more
doaj   +1 more source

Coupling Single Domain Antibodies to Catalytic Hairpin Assemblies for Homogeneous Assays

Advanced Sensor Research
Immunoassays are widely used in various fields, including biomedical research, clinical diagnostics, and environmental monitoring. Single domain antibodies (sdAbs) provide small, tailorable, recognition elements that have been integrated into ...
Jinny L. Liu, Dan Zabetakis, Lisa C. Shriver‐Lake, George P. Anderson, Ellen R. Goldman, Hieu Bui   +5 more
doaj   +1 more source

Editorial: Nanobody-based cancer immunotherapy and immunoimaging

Frontiers in Immunology, 2023
Mahdie Jafari, Amirhosein Maali, Mohammad Ali Shokrgozar, Zahra Sharifzadeh   +3 more
doaj   +1 more source

VNAR: shark single-domain antibodies for the new era of medical biotechnology. [PDF]

Front Immunol
Olivares-Olivares RA, Bravo AR, Garrido-Soto C, Carvajal JJ, Manubens A, Rivas M, Bustamente C, Retamal-Díaz A, Kalergis AM, Lay MK.   +9 more
europepmc   +1 more source

Editorial: Single-Domain Antibodies—Biology, Engineering and Emerging Applications

Frontiers in Immunology, 2018
Kevin A. Henry, C. Roger MacKenzie, C. Roger MacKenzie   +2 more
doaj   +1 more source

Selection and optimization strategy for Rap1-targeting single-domain antibodies as platelet activation markers. [PDF]

Res Pract Thromb Haemost
Alessi MC, Moulard M, Boulay-Moine D, Pons C, Margier M, Vessière C, Poggi M, Pigaglio T, Dignat-George F, Roussel A, Burtey S, Bonello L, Chames P, Bonjean R, Peiretti F.   +14 more
europepmc   +1 more source

A synergistic generative-ranking framework for tailored design of therapeutic single-domain antibodies. [PDF]

Cell Discov
Kong Y, Shi J, Wu F, Zhao T, Wang R, Zhu X, Xu Q, Song Y, Li Q, Wang Y, Gao X, Yang Y, Feng Y, Wang Z, Ge W, Wu Y, Yang Z, Yao J, Ying T.   +18 more
europepmc   +1 more source

Theranostic application of radiolabeled HER2-targeting single-domain antibodies (RAD202) in preclinical setting. [PDF]

Sci Rep
Altunay B, Obradović L, Florea A, Vogg ATJ, Schäfer L, Morgenroth A, Meszaros LK, Hertel F, Juweid ME, Mottaghy FM.   +9 more
europepmc   +1 more source