Results 101 to 110 of about 7,396,207 (304)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Soft Error-Tolerant and Highly Stable Low-Power SRAM for Satellite Applications

Applied Sciences
As CMOS technology has advanced, the transistor integration density of static random-access memory (SRAM) cells has increased. This has led to a reduction in the critical charge of sensitive nodes, making the SRAM cells more susceptible to soft errors ...
Jong-Yeob Oh, Sung-Hun Jo
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Frequency Dependence of Single-event Upset in Advanced Commerical PowerPC Microprocessors

, 2004
This paper examines single-event upsets in advanced commercial SOI microprocessors in a dynamic mode, studying SEU sensitivity of General Purpose Registers (GPRs) with clock frequency.
Irom, Frokh, Swift, Gary M., Johnston, Allen H., Farmanesh, Farhad F.   +3 more
core  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Dual-Level Fault-Tolerant FPGA-Based Flexible Manufacturing System

Designs
This paper proposes a fault-tolerant flexible manufacturing system (FMS) that features a dual-level fault tolerance mechanism at both the workcell and system levels to enhance reliability.
Gehad I. Alkady, Ramez M. Daoud, Hassanein H. Amer, Yves Sallez, Hani F. Ragai   +4 more
doaj   +1 more source

Mitigating multiple single-event upsets during deep neural network inference using fault-aware training

Deep neural networks (DNNs) are increasingly used in safety-critical applications. Reliable fault analysis and mitigation are essential to ensure their functionality in harsh environments that contain high radiation levels. This study analyses the impact
Dekkers, Gert, Prinzie, Jeffrey, Vinck, Toon, Karsmakers, Peter, Jonckers, Naïn   +4 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

First measurement of single event upsets in the readout control FPGA of the ALICE TPC detector

, 2011
This paper presents the first measurement of Single Event Upsets (SEUs) in the configuration memory of the readout control FPGA of the ALICE Time Projection Chamber. The measurements have been performed during pp collisions at a center-of-mass energy of (
Fehlker, D, J Alme, D Fehlker, C Lippmann, A Rehman, Lippmann, C, Alme, J, Rehman, A, Roed, K, K Røed   +9 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source