Results 1 to 10 of about 13,704 (180)
Pharmacologic Approach to Sinoatrial Node Dysfunction
Annual Review of Pharmacology and Toxicology, 2021 International audienceThe spontaneous activity of the sinoatrial node initiates the heartbeat. Sinoatrial node dysfunction (SND) and sick sinoatrial syndrome are caused by the heart's inability to generate a normal sinoatrial node action potential.
Pietro Mesirca +2 more
exaly +2 more sources
Molecular Pathway for the Localized Formation of the Sinoatrial Node
Circulation Research, 2007 The sinoatrial node, which resides at the junction of the right atrium and the superior caval vein, contains specialized myocardial cells that initiate the heart beat.
Mathilda T M Mommersteeg +2 more
exaly +3 more sources
Possible sinoatrial node dysfunction in a 6-month-old domestic shorthair cat. [PDF]
JFMS Open RepCase summary A six-month-old male entire domestic shorthair cat was presented to the ophthalmology department for nasolacrimal duct cannulation and flushing, and castration under general anaesthesia.
Hillen F, Locquet L.
europepmc +2 more sources
Journal of Molecular and Cellular Cardiology, 1985 The primary pacemaker, i.e. the group of pacemaker cells discharging the sinoatrial node comprises less than 1000 cells in the guinea-pig and about 5000 cells in the rabbit.
T Opthof, W K Bleeker, H J Jongsma
exaly +2 more sources
Assembly of the Cardiac Pacemaking Complex: Electrogenic Principles of Sinoatrial Node Morphogenesis
Journal of Cardiovascular Development and Disease, 2021 Cardiac pacemaker cells located in the sinoatrial node initiate the electrical impulses that drive rhythmic contraction of the heart. The sinoatrial node accounts for only a small proportion of the total mass of the heart yet must produce a stimulus of ...
Marietta R Easterling +2 more
exaly +2 more sources
Emerging Signaling Regulation of Sinoatrial Node Dysfunction. [PDF]
Curr Cardiol Rep, 2023 PURPOSE OF REVIEW: The sinoatrial node (SAN), the natural pacemaker of the heart, is responsible for generating electrical impulses and initiating each heartbeat.
Zheng M, Erhardt S, Cao Y, Wang J.
europepmc +2 more sources
Comparative study of sinoatrial node morphology and innervation
, 2016 [...]. Aim of and objectives of the study. The aim of the study: to identify limits and innervation of the sinoatrial node in hearts of mice, rabbits and pigs. Objectives: 1. To examine the distribution of pacemaker cells within the right atrium. 2.
Inokaitis, Hermanas
core +2 more sources
Emerging Regulatory Mechanisms in Sinoatrial Node Automaticity. [PDF]
J Cell Mol MedLiu H, Cao Y, Su X.
europepmc +3 more sources
Sinoatrial node heterogeneity and fibroblasts increase atrial driving capability in a two-dimensional human computational model. [PDF]
Front PhysiolBackground: Cardiac pacemaking remains an unsolved matter from many perspectives. Extensive experimental and computational studies have been performed to describe the sinoatrial physiology across different scales, from the molecular to clinical levels.
Ricci E +4 more
europepmc +2 more sources
Research Progress on Pathological Fibrosis of Sinoatrial Node [PDF]
, 2021 Human heart rhythm is mainly regulated and controlled by the sinoatrial node. Fibrosis plays an important regulating role in adjusting the structural and functional integrity of the sinoatrial node pacemaker complex.
WANG Wei, ZHANG Shi-lin, LIU Fang-fang, et al.
core +1 more source