Results 1 to 10 of about 469,611 (121)

Transcriptional profile of the rat cardiovascular system at single-cell resolution

Cell Reports
Summary: We sought to characterize cellular composition across the cardiovascular system of the healthy Wistar rat, an important model in preclinical cardiovascular research.
Alessandro Arduini, Stephen J. Fleming, Ling Xiao, Amelia W. Hall, Amer-Denis Akkad, Mark D. Chaffin, Kayla J. Bendinelli, Nathan R. Tucker, Irinna Papangeli, Helene Mantineo, Patricio Flores-Bringas, Mehrtash Babadi, Christian M. Stegmann, Guillermo García-Cardeña, Mark E. Lindsay, Carla Klattenhoff, Patrick T. Ellinor   +16 more
doaj   +1 more source

Rare Case of Rapidly Worsening REM Sleep Induced Bradycardia

Case Reports in Cardiology, 2015
Sinoatrial arrest also known as sinus pause occurs when sinoatrial node of the heart transiently ceases to generate the electrical impulse necessary for the myocardium to contract. It may last from 2.0 seconds to several minutes. Etiologies of sinoatrial
Ayyappa S. Duba, Suneetha Jasty, Ankit Mahajan, Vijay Kodadhala, Raza Khan, Prithviraj Rai, Mohammad Ghazvini   +6 more
doaj   +1 more source

Stress-induced pacemaker desynchronization in the sinoatrial node

Frontiers in Cardiovascular Medicine
The sinoatrial node (SAN) functions as a heterogeneous population of electrically coupled pacemaker cells rather than as a single dominant oscillator.
Dong-Gyun Han
doaj   +1 more source

Simplified 2D Bidomain Model of Whole Heart Electrical Activity and ECG Generation

Measurement Science Review, 2014
The aim of this study was the development of a geometrically simple and highly computationally-efficient two dimensional (2D) biophysical model of whole heart electrical activity, incorporating spontaneous activation of the sinoatrial node (SAN), the ...
Sovilj Siniša, Magjarević Ratko, Abed Amr Al, Lovell Nigel H., Dokos Socrates   +4 more
doaj   +1 more source

Genetics of sinoatrial node function and heart rate disorders

Disease Models & Mechanisms, 2023
Lieve E. van der Maarel, Alex V. Postma, Vincent M. Christoffels   +2 more
doaj   +1 more source

Cardiac conduction system malformations in heterotaxy result from dysregulated Pitx2 expression

JCI Insight
The cardiac conduction system (CCS) develops asymmetrically along the body axes. In heterotaxy syndrome — resulting from aberrant left-right axis formation — atrial and atrioventricular conduction defects can cause life-threatening arrhythmias.
Kunihiko Joo, Ryohei Matsuoka, Keiko Kitajima, Kenta Yashiro, Akira Shiose, Ryuji Tominaga, Michael M. Shen, Shinya Oki, Chikara Meno   +8 more
doaj   +1 more source

Complete Heart Block Lacking Functional Anatomical Impairment in the Conduction System

Pakistan Journal of Medicine and Dentistry
Introduction: Complete heart block also known as third-degree atrioventricular block (AV block) is a condition in which there is no conduction of the impulse produce in the sinoatrial node (SA node) in the atrium to the ventricle.1 Complete heart ...
Shazia Yasir, Komal Owais, Ishratullah
doaj  

Atypical form of sinoatrial node reentrant tachycardia: Should the traditional diagnostic criteria be modified?

HeartRhythm Case Reports
Shin Sakai, MD, Mitsunori Maruyama, MD, PhD, FHRS, Eiichiro Oka, MD, PhD, Kuniya Asai, MD, PhD   +3 more
doaj   +1 more source

Translational Anatomy of the Sinoatrial Node

JACC: Case Reports
Alejandro Jiménez Restrepo, MD, Mansour Razminia, MD, Damián Sánchez-Quintana, MD, PhD, José-Ángel Cabrera Rodriguez, MD, PhD   +3 more
doaj   +1 more source

Pharmacologic Approach to Sinoatrial Node Dysfunction

Annual Review of Pharmacology and Toxicology, 2021
International audienceThe spontaneous activity of the sinoatrial node initiates the heartbeat. Sinoatrial node dysfunction (SND) and sick sinoatrial syndrome are caused by the heart's inability to generate a normal sinoatrial node action potential.
Isabelle Bidaud, Peter J Mohler, Matteo E. Mangoni   +2 more
exaly   +2 more sources