Results 41 to 50 of about 1,321,275 (276)

Desmin is essential for the structure and function of the sinoatrial node; implications for increased arrhythmogenesis.

American Journal of Physiology. Heart and Circulatory Physiology, 2020
Our objective was to investigate the effect of desmin depletion on the structure and function of the sinoatrial pacemaker complex, (SANcl) and their implication in arrhythmogenesis.
M. Mavroidis, Nikolaos C. Athanasiadis, P. Rigas, I. Kostavasili, I. Kloukina, W. P. te Rijdt, N. Kavantzas, Dimitris Chaniotis, J. V. van Tintelen, I. Skaliora, C. Davos   +10 more
semanticscholar   +1 more source

CaMKII in sinoatrial node physiology and dysfunction

Frontiers in Pharmacology, 2014
The calcium and calmodulin-dependent protein kinase II (CaMKII) is present in sinoatrial node (SAN) pacemaker cells and is required for physiological "fight or flight" SAN beating rate responses. Inhibition of CaMKII in SAN does not affect baseline heart rate, but reduces heart rate increases in response to physiological stress.
Yuejin eWu, Mark E Anderson, Mark E Anderson   +2 more
openaire   +3 more sources

Gap junctions in the rabbit sinoatrial node [PDF]

American Journal of Physiology-Heart and Circulatory Physiology, 2001
In comparison to the cellular basis of pacemaking, the electrical interactions mediating synchronization and conduction in the sinoatrial node are poorly understood. Therefore, we have taken a combined immunohistochemical and electrophysiological approach to characterize gap junctions in the nodal area.
Marjan J. A. van Kempen, Sjoerd Postma, Habo J. Jongsma, Martin B. Rook, Sander Verheule   +4 more
openaire   +3 more sources

Sinoatrial node dysfunction and deafness

Definitions, 2020
Sinoatrial node dysfunction and deafness is a rare genetic disease characterized by congenital severe to profound deafness with no evidence of vestibular dysfunction, associated with sinoatrial node dysfunction with pronounced bradycardia and increased ...

semanticscholar   +1 more source

Genetic Abnormalities of the Sinoatrial Node and Atrioventricular Conduction

Cardiac Electrophysiology Clinics, 2021
The peculiar electrophysiological properties of the sinoatrial node and the cardiac conduction system are key components of the normal physiology of cardiac impulse generation and propagation. Multiple genes and transcription factors and metabolic proteins are involved in their development and regulation.
Porta Sánchez, Andreu, Giuliana Priori, Silvia   +1 more
openaire   +6 more sources

Tachycardia-bradycardia syndrome: Electrophysiological mechanisms and future therapeutic approaches (Review) [PDF]

, 2017
Sick sinus syndrome (SSS) encompasses a group of disorders whereby the heart is unable to perform its pacemaker function, due to genetic and acquired causes.
Chan, C, Chan, Y, Keung, W, Laxton, V, Li, K, Li, R, Liu, T, Tse, G, Wong, A   +8 more
core   +2 more sources

Bioelectronic Sensors for Neuromuscular Perception in Human‐Machine Interfaces

Advanced Robotics Research, EarlyView.
This review summarizes recent advances in bioelectronic sensors for neuromuscular perception in human‐machine interfaces. By integrating biopotential, electrical impedance, and electrochemical sensing strategies with flexible electrode interfaces, these bioelectronic sensing systems enable intuitive, real‐time detection of muscle and nerve activity ...
Junwei Li, Bangyan Niu, Kunlin Wu, Jingcheng Xiao, Xiaoyan Liu, Yifan Wang   +5 more
wiley   +1 more source

Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice

Advanced Science, EarlyView.
PSTNVglut2 neurons function as a new central baroreflex hub via projections to the NTS, modulating parasympathetic cardiac output to maintain cardiovascular homeostasis while synchronously regulating locomotion. Blood pressure fluctuations negatively correlate with locomotor performance.
Ming‐Xuan Lu, Jin‐Yin Huang, Xing‐Zhe Xu, Ji‐Yu Sun, Dan‐Ni Zou, Jia‐Yao Zhang, Chen Chi, Qi Zhang, Wei‐Cai Liu   +8 more
wiley   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

The Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna, Donald B. Hoover, Logan G. Kirkland, Elizabeth H. Smith, Megan D. Poston, Stanley G. Peirce, Chloe G. Garbe, Steven Cha, Shumpei Mori, Jaclyn A. Brennan, John Andrew Armour, Eric Rytkin, Igor R. Efimov, Olujimi A. Ajijola, Jeffrey L. Ardell, Kalyanam Shivkumar   +15 more
wiley   +1 more source

Emotional intelligence buffers the effect of physiological arousal on dishonesty [PDF]

, 2018
We studied the emotional processes that allow people to balance two competing desires: benefitting from dishonesty and keeping a positive self-image. We recorded physiological arousal (skin conductance and heart rate) during a computer card game in which
A Bechara, A Furnham, A Pittarello, A Pittarello, A Tenbrunsel, Andrea Pittarello, AR Damasio, Beatrice Conte, BM Appelhans, E Rubaltelli, EJ Austin, Enrico Rubaltelli, G Coricelli, G Grolleau, G Hochman, GG Berntson, GW Allport, H Eisenbarth, J Gu, JF Brosschot, JM Wilkinson, JS Cameron, JT Cacioppo, KV Petrides, KV Petrides, KV Petrides, KV Petrides, LK Treviño, M Mikolajczak, M Mikolajczak, M Rosenberg, Marta Caserotti, MC Kern, ME Schweitzer, MM Bradley, N Mazar, P Slovic, R Barkan, R Teper, R Teper, RA Dienstbier, RJ Barry, RJ Croft, RJ Wright, RS Lazarus, S Ayal, S Ayal, S Cote, S Laborde, S Schindler, S Shalvi, S Shalvi, S Shalvi, S Shalvi, Sara Scrimin, SD Kreibig, W Boucsein   +56 more
core   +2 more sources