Results 71 to 80 of about 1,311,541 (283)

Changes in gap junction proteins Connexin30.2 and Connexin40 expression in the sinoatrial node of rats with dexmedetomidine-induced sinus bradycardia

open access: yesBrazilian Journal of Anesthesiology, 2022
Background: Dexmedetomidine (Dex) is widely used, and its most common side effect is bradycardia. The complete mechanism through which Dex induces bradycardia has not been elucidated.
Yong-Qiang Yin   +3 more
doaj  

Mathematical Models of Cardiac Pacemaking Function

open access: yesFrontiers in Physics, 2013
Over the past half century, there has been intense and fruitful interaction between experimental and computational investigations of cardiac function. This interaction has, for example, led to deep understanding of cardiac excitation-contraction coupling;
Pan eLi   +3 more
doaj   +1 more source

Endogenous driving and synchronization in cardiac and uterine virtual tissues: bifurcations and local coupling [PDF]

open access: yes, 2006
Cardiac and uterine muscle cells and tissue can be either autorhythmic or excitable. These behaviours exchange stability at bifurcations produced by changes in parameters, which if spatially localized can produce an ectopic pacemaking focus.
Benson, A.P.   +4 more
core   +1 more source

Sinoatrial nodal disease presenting with tachy-bradycardia syndrome in a fetus of anti-SSA/SSB-positive mother

open access: yesAnnals of Pediatric Cardiology, 2022
Tachy-bradycardia syndrome (TBS) has been reported rarely in the fetus. We present here an unusual dominant involvement of sinoatrial node in a fetus presenting with TBS of anti-Sjögren'syndrome-related antigen A (SS-A) and antigen B (SS-B ...
Balaganesh Karmegaraj
doaj   +1 more source

Late‐onset asystole associated with vagal nerve stimulation

open access: yesEpilepsia Open, EarlyView.
Abstract Vagal nerve stimulation (VNS) is a form of neuromodulation that is an established adjunct in the management of drug‐resistant epilepsy. The common side effects of VNS are cough, dysphonia, or shortness of breath, which are often mild and do not require discontinuation of therapy.
Divya Nagabushana   +3 more
wiley   +1 more source

Modulated parasystole originating in the sinoatrial node. [PDF]

open access: yesCirculation, 1986
A computer model of "modulated sinus parasystole" was devised in which two sinus pacemakers interacted electrotonically, entraining each other's periodicity according to their beat-to-beat phasic relationships. Depending on the preestablished rules, the model gave rise to various rhythm patterns that were similar to those recorded in patients with ...
José Jalife, D C Michaels, R Langendorf
openaire   +3 more sources

Generation of a human embryonic stem cell line (WAe009-A-78) carrying homozygous TBX18 knockout

open access: yesStem Cell Research, 2022
T-Box Transcription Factor 18 is a member of the T-box family, encoding TBX18 protein. As a transcriptional repressor, it related to developmental processes of a majority of tissues and organs and plays crucial part in the embryonic development of ...
Qi Xu   +5 more
doaj  

Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program

open access: yesDevelopment, 2019
The rate of contraction of the heart relies on proper development and function of the sinoatrial node, which consists of a small heterogeneous cell population, including Tbx3+ pacemaker cells. Here, we have isolated and characterized the Tbx3+ cells from
Vincent W. W. van Eif   +9 more
semanticscholar   +1 more source

Chronic atrial and intestinal dysrythmia syndrome: A late‐onset intestinal pseudo‐obstruction and cardiac dysfunction due to an SGO1 mutation

open access: yesJPGN Reports, EarlyView.
Abstract Objectives Pediatric intestinal pseudo‐obstruction (PIPO) is a rare, heterogeneous, and severe gut motility disorder. In 2014, Chetaille et al. described chronic atrial and intestinal dysrhythmia (CAID) syndrome associated with a recessive SGO1 mutation (p.Lys23Glu) linking it to both intestinal pseudo‐obstruction and cardiac dysrhythmia. This
Linda Adouane   +4 more
wiley   +1 more source

Overexpression of a Neuronal Type Adenylyl Cyclase (Type 8) in Sinoatrial Node Markedly Impacts Heart Rate and Rhythm

open access: yesFrontiers in Neuroscience, 2019
Heart rate (HR) and HR variability (HRV), predictors of over-all organism health, are widely believed to be driven by autonomic input to the sinoatrial node (SAN), with sympathetic input increasing HR and reducing HRV. However, variability in spontaneous
Jack M. Moen   +15 more
semanticscholar   +1 more source

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