Results 71 to 80 of about 1,344,270 (316)

Three-dimensional computer model of the right atrium including the sinoatrial and atrioventricular nodes predicts classical nodal behaviours.

PLoS ONE, 2014
The aim of the study was to develop a three-dimensional (3D) anatomically-detailed model of the rabbit right atrium containing the sinoatrial and atrioventricular nodes to study the electrophysiology of the nodes. A model was generated based on 3D images
Jue Li, Shin Inada, Jurgen E Schneider, Henggui Zhang, Halina Dobrzynski, Mark R Boyett   +5 more
doaj   +1 more source

Effect of Cilnidipine on L- and T-type Calcium Currents in Guinea Pig Ventricle and Action Potential in Rabbit Sinoatrial Node

Journal of Pharmacological Sciences, 2004
Cilnidipine, a dihydropyridine Ca2+ channel antagonist, is known to have inhibitory effects on both L- and N-type Ca2+ currents. In the present study, we examined the effect of cilnidipine on myocardial L- and T-type Ca2+ currents and sinoatrial node ...
Kentaro Takeda, Reiko Yamagishi, Haruko Masumiya, Hikaru Tanaka, Koki Shigenobu   +4 more
doaj   +1 more source

Help system for medical diagnosis of the electrocardiogram [PDF]

, 2011
This presentation is part of a work that aims to create an interactive learning medical system of ECG events and pathologies diagnose. The system can be seen as an interactive game in wish the user will practice with ECG signal of several pathologies For
Lopes, Vanda, Teixeira, João Paulo
core   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

The effect of gag reflex on cardiac sympatovagal tone [PDF]

, 2012
Objectives: Heart velocity may be influenced by gagging. The medulla oblongata receives the afferents of gag reflex. Neuronal pools of vomiting, salivation and cardiac parasympathetic fibers are very close in this area.
Jamshir, M., Maleki, A., Mehran Hosseini, S.   +2 more
core   +2 more sources

Impact of functional studies on exome sequence variant interpretation in early-onset cardiac conduction system diseases [PDF]

, 2020
Aims The genetic cause of cardiac conduction system disease (CCSD) has not been fully elucidated. Whole-exome sequencing (WES) can detect various genetic variants; however, the identification of pathogenic variants remains a challenge.
Asano, Yoshihiro, Beerens, Manu, Burch, Micah L, Buys, Eva, Chiang, David Y, Cui, Shihe, Fujino, Noboru, Fujita, Takashi, Funada, Akira, Furusho, Hiroshi, Hayashi, Kenshi, Hodatsu, Akihiko, Inoue, Masaru, Kaku, Bunji, Kato, Takeshi, Kawashiri, Masa-aki, Kelly, Amy E, Kita, Yoshihito, Kiviniemi, Tuomas O, Kobayashi, Isao, Konno, Tetsuo, Kurata, Yasutaka, MacRae, Calum A, Nagata, Yoji, Nakanishi, Chiaki, Namura, Masanobu, Nomura, Akihiro, Oe, Kotaro, Okada, Hirofumi, Onoue, Kenji, Saito, Yoshihiko, Sakamoto, Yuichiro, Sakata, Kenji, Sips, Patrick, Tada, Hayato, Takamura, Masayuki, Takashima, Seiji, Takeda, Yuko, Tanaka, Yoshihiro, Teramoto, Ryota, Tsuchiya, Taketsugu, Tsuda, Toyonobu, Usuda, Keiich, Yamagishi, Masakazu, Zhao, Yanbin   +44 more
core   +1 more source

An Anisotropic and Stable‐Conductance Patch for Mechanical–Electrical Coupling With Infarcted Myocardium

Exploration, EarlyView.
Inspired by the hierarchical structures of native myocardium, an anisotropic and conductance‐stable myocardial patch is designed. The patch, which aligns with the native tissue's anisotropic characteristics is engineered to provide infarcted myocardium with directionally electrical conduction and anisotropic mechanical support, achieving mechanical ...
Yimeng Li, Yuchen Miao, Leqian Wei, Wenxin Li, Mengqi Shan, Qianqian Jiang, Fujun Wang, Lu Wang, Ze Zhang, Jizhou Song, Yang Zhu, Jifu Mao   +11 more
wiley   +1 more source

Mathematical Models of Cardiac Pacemaking Function

Frontiers in Physics, 2013
Over the past half century, there has been intense and fruitful interaction between experimental and computational investigations of cardiac function. This interaction has, for example, led to deep understanding of cardiac excitation-contraction coupling;
Pan eLi, Glenn T. Lines, Mary M. Maleckar, Aslak eTveito   +3 more
doaj   +1 more source

Optimizing the integration of modern systemic therapies and advanced radiotherapy techniques in breast cancer management: An expert opinion from the Institut Curie Breast Radiotherapy Group

International Journal of Cancer, EarlyView.
Abstract The integration of modern systemic therapies with radiotherapy (RT) represents a promising strategy in breast cancer management, enhancing both locoregional control and systemic disease outcomes. This expert consensus from the Institut Curie Breast Radiotherapy Group focuses exclusively on modern systemic agents, synthesizing current evidence ...
Cezara Cheptea, Pierre Loap, Sofiane Allali, Alain Fourquet, Kim Cao, Youlia Kirova   +5 more
wiley   +1 more source

Sinoatrial nodal disease presenting with tachy-bradycardia syndrome in a fetus of anti-SSA/SSB-positive mother

Annals of Pediatric Cardiology, 2022
Tachy-bradycardia syndrome (TBS) has been reported rarely in the fetus. We present here an unusual dominant involvement of sinoatrial node in a fetus presenting with TBS of anti-Sjögren'syndrome-related antigen A (SS-A) and antigen B (SS-B ...
Balaganesh Karmegaraj
doaj   +1 more source