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Bioinformatics of siRNA Design
2013RNA interference mediated by small interfering RNAs is a powerful tool for investigation of gene functions and is increasingly used as a therapeutic agent. However, not all siRNAs are equally potent, and although simple rules for the selection of good siRNAs were proposed early on, siRNAs are still plagued with widely fluctuating efficiency.
openaire +3 more sources
Annealing siRNAs to Produce siRNA Duplexes
Cold Spring Harbor Protocols, 2006openaire +3 more sources
Topical antiviral siRNA: A practical siRNA microbicide? [PDF]
Gene Therapy, 2006 openaire +1 more source