THE siRNA EFFICACY OF SOLUBLE ACID INVERTASE DOWN-REGULATION IN SUGARCANE (SACCHARUM SPP.) [PDF]
Sugarcane (Saccharum sp. hybrids) is a C4 grass used as a major source of sucrose. Invertase enzymes hydrolyse sucrose into hexose sugars reducing the production markedly.
Shereen K.M. Khaled +4 more
doaj +1 more source
PENGENDALIAN PERILAKU MENYIMPANG SISWA DILIHAT DARI PERAN ORANG TUA DAN GURU DI SMP ISLAM AL-ISTIQOMAH DEPOK [PDF]
Beragamnya perilaku menyimpang yang dilakukan siswa di sekolah, menjadi perhatian khusus bagi guru sebagai agen penting yang bertanggung jawab menangani permasalahan ini di sekolah. Semua itu tidak akan berjalan sesuai dengan yang diharapkan tanpa adanya
Fitakila, Sirna
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
siRNA Selection Server: an automated siRNA oligonucleotide prediction server [PDF]
The Whitehead siRNA (short interfering RNA) Selection Web Server (http://jura.wi.mit.edu/bioc/siRNA) automates the design of short oligonucleotides that can specifically 'knock down' expression of target genes. These short sequences are about 21 nt in length, and when synthesized as double stranded RNA and introduced into cell culture, can reduce or ...
Yuan, B. +4 more
openaire +3 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Nanodiamond as a vector for siRNA delivery to Ewing sarcoma cells
We investigated the ability of diamond nanoparticles (nanodiamonds, NDs) to deliver small interfering RNA (siRNA) in Ewing sarcoma cells, in the perspective of in vivo anti-cancer nucleic acid drug delivery.
Barnard +47 more
core +3 more sources
Ku80 Counters Oxidative Stress-Induced DNA Damage and Cataract Formation in the Human Lens [PDF]
PURPOSE: Oxidative stress in the human lens leads to a wide range of damage including DNA strand breaks, which are likely to contribute to cataract formation.
Ball, Simon Sidney Robert +4 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The OP Protein Cage: A Versatile Molecular Delivery Platform
Well-defined containers constructed from multiple protein subunits are a unique class of nanomaterial useful in supramolecular chemistry and biology. These protein cages are widespread in nature, where they are responsible for a diversity of important ...
Thomas G.W. Edwardson +2 more
doaj +1 more source
Separase prevents genomic instability by controlling replication fork speed [PDF]
Proper chromosome segregation is crucial for preserving genomic integrity, and errors in this process cause chromosome mis-segregation, which may contribute to cancer development.
Cucco, Francesco +11 more
core +4 more sources

